Work Schedule Standard (Mon-Fri) Environmental Conditions Office
Job Description
Position: Senior Scientist
ONSITE:
This is a fully onsite role based at our customer’s site in (Gaithersburg, Maryland). We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate. Must be legally authorized to work in the United States without sponsorship. Must be able to pass a comprehensive background check, which includes a drug screening.
At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.
Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner. Our Laboratories Functional Service Partnership (FSP) team plays a direct role in advancing drug development by creating sustained groups of talent within our customers’ organizations to provide long-term support. Through this collaborative approach, our professionals bring their commitment to excellence, industry knowledge, and operational strength directly into customer environments, helping to enhance capabilities and advance the delivery of life-changing therapies.
Key responsibilities:
- This candidate will deliver ligand-binding testing associated with departmental pharmacokinetic (PK) and pharmacodynamic (PD) studies. This is a hands-on, laboratory-based assignment focused on timely sample analysis and generation of accurate, traceable, fit-for-purpose bioanalytical data.
- Candidate will work to develop or work from approved methods, protocols, study plans, and departmental procedures; coordinate testing priorities with designated scientific leads; and independently
- execute routine assay activities. Work may include assay readiness checks, reagent and sample preparation, plate execution, data review, repeat analysis when scientifically justified, and preparation of study-level data packages.
- The assignment is delivery-oriented. They are expected to manage agreed work efficiently, escalate risks promptly, and maintain complete records sufficient for scientific review and downstream reporting. Final priorities, study volume, and schedules will be set by the department based on portfolio needs.
- Develop and/or Execute ligand-binding assays for PK and PD sample testing using established methods and approved study documentation. Additional responsibilities for assay delivery may be assigned in accordance with department needs (e.g. flow cytometry assay development and/or testing if applicable).
- Prepare samples, standards, controls, reagents, and assay plates; operate applicable laboratory instrumentation and software.
- Complete assay readiness activities, including reagent checks, control evaluation, and method familiarization or training.
- Review run performance against predefined acceptance criteria and identify, document, and communicate assay issues or deviations.
- Perform scientifically justified repeat analysis and basic troubleshooting in consultation with the designated scientific lead.
- Analyze and process data using approved templates and systems, ensuring accuracy, traceability, and appropriate quality control.
- Maintain contemporaneous records in electronic laboratory notebooks, sample-management systems, and other departmental repositories.
- Prepare complete data packages, summaries, and supporting documentation for scientific review and reporting.
- Track assigned workload, turnaround times, and dependencies; provide concise status updates and escalate delivery risks promptly.
- Follow applicable safety, biosafety, data-integrity, confidentiality, and departmental procedures.
- Coordinate effectively with project scientists, sample-management colleagues, and other internal partners.
Education and Experience:
- Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’) OR Masters degree
Knowledge, Skills and Abilities:
- Experience testing nonclinical or clinical study samples in a pharmaceutical, biotechnology, or contract research environment.
- Experience with automated ligand-binding assay workflows and high-throughput sample testing.
- Familiarity with fit-for-purpose assay qualification, regulated or GxP-like practices, and technical report support.
- Experience with biomarker, target-engagement, or receptor-occupancy assays.
- Experience with other bioanalytic modalities, particularly flow cytometry would be beneficial but is not required.
- Completed PK and PD ligand-binding assay runs and sample analyses aligned with approved schedules and acceptance criteria.
- Accurate, complete, and review-ready data packages delivered within agreed turnaround times.
- Contemporaneous and traceable laboratory, sample, and data records with no unresolved documentation gaps.
- Prompt communication of assay failures, sample issues, capacity constraints, and schedule risks, with recommended next steps.
Working Environment:
Below is listed the working environment/requirements for this role:
Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner. Able to work upright and stationary and/or standing for typical working hours. Able to lift and move objects up to 25 pounds Able to work in non-traditional work environments. Able to use and learn standard office equipment and technology with proficiency. May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments. Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
Benefits
We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!
Compensation and Benefits The salary range estimated for this position based in Maryland is $75,000.00–$95,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
- A choice of national medical and dental plans, and a national vision plan, including health incentive programs
- Employee assistance and family support programs, including commuter benefits and tuition reimbursement
- At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
- Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
- Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards