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Insight Global

Surface Plasmon Resonance Scientist

Upper Providence, PA, United States

From $51 USD / hour

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Job details

Pay: From $51 USD / hour
Posting language: English
Posted: Sep 29, 2026

Original job description

Required Skills & Experience

-Bachelors, Masters, or PHD with significant industry experience in Biochemistry, Biophysics, Protein Sciences, Molecular Biology, Chemical Biology, or related scientific discipline. -Hands-on experience with Surface Plasmon Resonance (SPR) technologies. -Biophysical characterization -Experience generating and interpreting protein-protein or antibody-antigen interaction data. -Strong understanding of binding kinetics and affinity measurements.

Nice to Have Skills & Experience

Direct experience with Carterra LSA or Carterra LSA XT platforms.

Job Description

We are seeking an an experienced biophysics scientist to support an AI-enabled antibody discovery initiative. The successful candidate will generate high-quality quantitative Surface Plasmon Resonance (SPR) datasets using the Carterra LSA XT high-throughput SPR platform to support development and training of in silico antibody design models. The role combines biophysical experimentation, kinetic data analysis, assay execution, data quality management, and cross-functional collaboration with computational and AI scientists.

Key Responsibilities:

-Independently operate and maintain the Carterra LSA XT high-throughput SPR platform. -Execute affinity and kinetic characterization experiments for large numbers of antibody and protein designs. -Perform sensor chip preparation, protein immobilization, assay setup, and experimental execution. -Utilize validated protocols to support high-throughput screening activities. -Troubleshoot assay performance and optimize experimental conditions as needed

-Generate high-quality kinetic and affinity datasets, including:

-KD (binding affinity) -kon (association rate) -koff (dissociation rate) -Analyze and validate experimental data to ensure accuracy and reproducibility. -Process and prepare datasets for downstream AI and machine learning applications. -Document all experimental activities, analyses, and outcomes within GSK Electronic Laboratory Notebook (ELN) systems.

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Skills

Molecular biology
Data analysis
Quality assurance procedures
Collaboration
Troubleshoot

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