For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Overview
Your primary responsibilities include the timely development of new and innovative NGS service offerings. You will liaise closely with internal and external stakeholders. You will be responsible for the design, development, and optimization, and introduction of new NGS services. You will be expected to lead by example and work collaboratively to advance the application of NGS in the field of biosafety testing.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
- Contribute scientific and technical expertise for new and innovative NGS applications
- Evaluate emerging trends in our industry including technical advances with NGS technologies and related bioinformatics
- Act as scientific resource for our development and commercial operations teams
- Develop and apply laboratory techniques and skills to design, support and/or drive execution of experiments. This is a hands-on laboratory-based position.
- Provide bioinformatics (project-specific) support as needed. Use bioinformatics experience to perform data analysis independently, as needed, and work closely with the bioinformatics team to provide user specifications/expectations that are specific for the project.
- Ensure testing is performed in accordance with applicable SOPs and regulations
- Maintain complete and comprehensive records for assay development, assay application/execution, and study integrity
- Write technical reports; prepare, publish and/or present scientific data, abstracts, papers, posters, etc. to advance the reputation and recognition of the organization
- Participate in consortia, conferences, and other forums to promote our ongoing activities
- Play an integral role in process improvement; promote a culture of continuous improvement and act as a champion for initiatives to drive quality improvement
- Represent the group during internal and external audits, client meetings and communications. Respond to audit observations, complaints and CAPAs
- Provide mentoring, scientific coaching and support other team members
- May perform other related duties as required and/or assigned
Job Description
QUALIFICATIONS:
- Education: Ph.D. (preferred) in molecular biology, biotechnology, bioinformatics, or a related field
- Experience: minimum of three (3) years of hands-on laboratory experience with NGS and new assay design and development in an industrial environment
- An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above: Bachelor’s or Master’s degree in molecular biology, biotechnology, bioinformatics, or a related field with a minimum of 10 years (for Bachelor’s) or seven (7) years (for Master’s) of hands-on experience with NGS and new assay design and development in an industrial environment
- Advanced understanding and application of design of experiments (DOE) is desired
- Experience with bioinformatics tools and processes for data evaluation is a plus
- Experience with programming languages (e.g., Perl, Python, R) is a plus
- Extensive working knowledge and hands-on experience executing and overseeing highly technical projects and/or related studies (e.g., molecular biology, sequencing)
- Proven experience leading and/or supervising staff in a commercial laboratory setting such as a contract research laboratory, with emphasis in a GxP environment.
- Broad working knowledge of the field of NGS and hands-on experience with relevant molecular biology laboratory practices, techniques, equipment, materials, and mathematical calculations.
- Strong molecular biology skills, especially related to NGS
- Highly proficient in use of advanced laboratory techniques, equipment, and materials
- Other: Knowledge of cGMPs or regulatory affairs pertaining to the pharmaceutical and biological industries is preferred. Must possess excellent interpersonal skills to maintain communication across biological functional groups. Demonstrate a high degree of leadership. Effective coaching and training (or supervisory where relevant) skills for complex and highly technical work. Broad working knowledge of laboratory policies and assays, as well as corporate goals. Excellent time management skills. Ability to collaborate and work independently. Able to communicate effectively in a group or one on one setting. Advanced skills in applicable computer programs
Compensation Data
The pay rate for this role is $105,000 - $110,000 per year. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
About Biologics Testing Solutions With more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs. Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.
About Charles River Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.
Equal Employment Opportunity
Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit www.criver.com.