Jobs in the United States

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Added 4 mins ago
Senior Software Engineer
VTG
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Bachelor's Degree with atleast 5 years of experience required
Added 4 mins ago
Electronic Security Systems Engineer
VTG
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VTG is seeking an Electronic Security Systems Engineer to support our customer in Pearl City, Hawaii.
Added 10 mins ago
I
Salesforce Commerce Cloud Dev Ops/Release Engineer
iSoftStone
New York, NY
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Added 16 mins ago
Lead Testing & Commissioning Engineer
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TRC, Member of WSP, is a global consulting environmental and engineering firm and one of the top design firms in the energy sector. Together, TRC and WSP’s 83,000 experts create positive,…
Added 16 mins ago
Project Engineer III
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Added 17 mins ago
Spacesuit Project Engineer
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We have an exciting opportunity for a Spacesuit Project Engineer to join the JETSII Contract with Astrion.
Added 17 mins ago
Senior System Safety Engineer
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Eglin Air Force Base, FL
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Added 17 mins ago
Communications/Navigation Engineer, Principal
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Added 21 mins ago
GxP Lab Computing Engineer
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The Zifo Lab Computing Engineer provides both consulting, analytical and technical laboratory services, including multivendor instrument, information technology as well as in-lab…
Added 21 mins ago
GxP Lab Computing Engineer
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The Zifo Lab Computing Engineer provides both consulting, analytical and technical laboratory services, including multivendor instrument, information technology as well as in-lab…
Added 21 mins ago
Sr. Automation Engineer
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Remote, United States
Zifo is seeking an experienced Scientific Automation Lead to drive the design, architecture, and delivery of scalable, compliant automation solutions across scientific and laboratory…
Added 21 mins ago
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Senior Data Engineer
Zifo
Remote, United States
- $100,000 to $130,000 USD / year
Design, build, and operate the data infrastructure for a clinical trial design platform that extracts insights from clinical protocols, regulatory documents, and published articles to…
Added 22 mins ago
Senior Development Engineer
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The Senior Development Engineer will lead the design, development, and testing of innovative medical devices, surgical instruments, and orthopedic components.
Added 22 mins ago
Senior Data Engineer
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Remote, United States
The Senior Data Engineer will lead the design, development, and optimization of enterprise data architectures and business intelligence solutions.
Added 22 mins ago
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CyberSecurity Engineer III
Jobgether
Remote, United States
- $120,000 to $180,000 USD / year
ITIL Foundation certification required
Added 22 mins ago
Keystone Electric - Project Estimator
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…technological, and contracting needs of integrated systems from design-build services through project deployment. We provide the highest level of experienced partnership to our clients…
Added 24 mins ago
Staff Service Systems Engineer
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Added 24 mins ago
Staff Field Service Engineer
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Added 28 mins ago
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…by technology and innovation, but also perpetually driven to design, develop, and test as a trusted partner for Fortune 500 customers. As a team of remarkably diverse engineers, we…
Added 32 mins ago
Senior Thermal Engineer
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As a Senior Thermal Engineer, you will serve as the technical authority for Divergent’s aero-structures portfolio, responsible for pushing the envelope of our technology with respect to…
Added 32 mins ago
Staff Systems Engineer
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As a Staff Systems Engineer at Halo Industries, you will play a crucial role in the development, integration, and lifecycle management of our next-generation semiconductor manufacturing…
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The Cement Engineer monitors cement blend performance, designs, and directs testing of cement blend processing procedures, designs quality assurance tests, evaluates technical…
Added 33 mins ago
Physical IC Layout Engineer – Analog / PMIC
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Added 36 mins ago
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…semiconductor manufacturing equipment. You’ll provide engineering and design oversight for final hookups - including power distribution, grounding, and low‑voltage communications - while…
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Zifo

Senior Data Engineer

Remote, United States

$100,000 to $130,000 USD / year

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Job details

Pay: $100,000 to $130,000 USD / year
Posting language: English
Posted: Oct 22, 2026

Original job description

Design, build, and operate the data infrastructure for a clinical trial design platform that extracts insights from clinical protocols, regulatory documents, and published articles to accelerate trial design decisions. This role owns the pipelines that ingest, parse, transform, and serve clinical data - from raw PDF extraction through structured storage in Aurora and GraphDB, to serving curated knowledge for LangGraph-based agentic AI workflows.

Build ingestion pipelines for clinical trial protocols, ICF documents, SmPCs, CSRs, and published articles (PubMed, CTIS, ClinicalTrials.gov) - handling PDF parsing, text extraction, and structured data normalization
Design and implement data models in Amazon Aurora (relational) and GraphDB (knowledge graph) to represent trial design entities: endpoints, eligibility criteria, study arms, interventions, therapeutic areas, and their relationships
Develop embedding and vectorization pipelines to prepare extracted clinical text for RAG-based retrieval in LangGraph agentic workflows - chunking strategies, metadata enrichment, and vector store population
Build and maintain ETL/ELT workflows that transform unstructured clinical content into queryable, linked data across both relational and graph stores
Implement data quality validation specific to clinical data - protocol section classification accuracy, entity extraction completeness, cross-reference integrity (NCT IDs, EudraCT numbers, MeSH terms)
Build data serving APIs (Python/FastAPI) that expose curated datasets to the Angular frontend and LangGraph agent layer
Set up data lineage tracking and audit trails to support regulatory traceability of AI-generated trial design recommendation

Required Skills

Strong Python development experience, including PDF/document parsing libraries such as PyMuPDF, pdfplumber, unstructured.io, or similar.
Advanced PostgreSQL-compatible SQL, including Amazon Aurora; experience with schema design, migrations, query optimization, and indexing strategies for large clinical datasets.
Hands-on experience with Neptune, Neo4j, or similar graph databases; proficiency in SPARQL or Cypher; experience with ontology and knowledge graph modeling for biomedical entities.
Experience with AWS services including Aurora PostgreSQL, S3, Lambda, Step Functions, SQS/SNS, and IAM, particularly for data pipeline orchestration.
Experience with PDF text extraction, document section classification, and named entity recognition (NER) for clinical/biomedical text; familiarity with embedding models and vector stores such as OpenSearch, pgvector, or Pinecone.
Experience building data-serving APIs using FastAPI, including asynchronous programming patterns and backend integration.
Experience preparing data for LangChain/LangGraph applications and designing RAG pipelines, including chunking, retrieval, reranking, and prompt-data integration.
Experience with Airflow, Prefect, AWS Step Functions, Temporal, or similar workflow orchestration tools; ability to design multi-stage DAGs with dependency management, retry logic, monitoring, and error handling.
Experience with Terraform or AWS CDK, Docker, and Git, including automated pipeline testing and deployment on AWS.

Domain Knowledge

Understanding of clinical trial structure: protocol sections (objectives, endpoints, eligibility criteria, study design, statistical considerations)
Familiarity with clinical data standards or terminologies (MeSH, MedDRA, SNOMED, ATC codes, CDISC) is a strong plus
Awareness of regulatory data integrity requirements (21 CFR Part 11, EU Annex 11, ALCOA+ principles)

Nice to Have

Experience with biomedical knowledge graphs (e.g., linking drugs -> targets -> diseases > trials)
Prior work with PubMed/MEDLINE data, ClinicalTrials.gov API, or EMA/CTIS data.
Apache Spark or Databricks for batch processing of large document corpora
dbt for transformation layer management over Aurora

CURIOSITY DRIVEN, SCIENCE FOCUSED, EMPLOYEE BUILT. Our culture is unlike any other, one where we debate, challenge ourselves, and interact with all alike. We are a curious bunch, characterized by our passion to learn and spirit of teamwork. Zifo is a global R&D solutions provider focused on the industries of Pharma, Biotech, Manufacturing QC, Medical Devices, specialty chemicals and other research-based organizations. Our team’s knowledge of science and expertise in technology help Zifo better serve our customers around the globe, including 18 of the Top 20 Biopharma companies. We look for Science – Biotechnology, Pharmaceutical Technology, Biomedical Engineering, Microbiology etc. We possess scientific and technical knowledge and bear professional and personal goals. While we have a “no doors” policy to promote free access within, we do have a tough door to walk in. We search with a two-point agenda – technical competency and cultural adaptability. We offer a competitive compensation package including accrued vacation, medical, dental, vision, 401k with company matching, life insurance, and flexible spending accounts. If you share these sentiments and are prepared for the atypical, then Zifo is your calling! Zifo is an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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More about this job

Skills

Data models
Data engineering
Python
PostgreSQL
SQL
Neo4j
SPARQL
AWS
Identity and access management
LangChain
Apache Airflow
Workflow
IBM Terraform
Docker
Git
Apache Spark
Databricks
dbt
Biotechnology
Pharmaceutical technology
Biomedical engineering
Adaptability

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Jobs in the United States