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Mechanical Engineering Co-op (Spring 2027)
Emerson
Rockford, IL
Engineering Lab – Exposure to a variety of products in our product line working closely with lab technicians and engineers to assist in conducting ‘hands-on’ feasibility studies of new…
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Electrical Engineering Co-op (Spring 2027)
Emerson
Rockford, IL
Engineering Lab – Exposure to a variety of products in our product line working closely with lab technicians and engineers to assist in conducting ‘hands-on’ feasibility studies of new…
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Project Manager
The Hertz Corporation
Springfield, IL
Partner with product management, engineering, UX/UI, QA, analytics, marketing, operations, and support teams to align priorities and execute launches successfully.
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Sr Manager of Fusion Applications (Greenfield)
Oracle
Springfield, IL
- $136,700 to $243,800 USD / year
…Communications, Media & Entertainment, Utilities, and Construction &…
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Senior Director Software Engineering
Capital One
Springfield, IL
Continuously improve software engineering practices
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CrowdStrike Platform Senior Resident Consultant (Remote)
CrowdStrike
Springfield, IL
Utilize and engineer native and 3rd party software deployment technologies
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Senior Front-End and Agentic-UI Engineer
Evolent
Springfield, IL
Utilize approved AI-assisted engineering tools, such as GitHub Copilot, to accelerate software development, testing, documentation, troubleshooting, and analysis activities.
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Business Development Manager OEM
Emerson
Springfield, IL
…Working closely with sales, product management, application engineering, industry leaders, and channel partners, you will help influence equipment specifications, build long-term…
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Core Senior .NET Software Engineer
Evolent
Springfield, IL
Utilize approved AI-assisted engineering tools to accelerate software development, testing, documentation, troubleshooting, and analysis activities.
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Sr Field Service Technician
Honeywell Technologies
Springfield, IL
YOU MUST HAVE
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Director Sales, Connected Services
Honeywell Technologies
Springfield, IL
- $198,000 to $285,000 USD / year
YOU MUST HAVE:
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Analytics Program Manager
Meta
Springfield, IL
…builds connections across disparate team members including engineering, data science, and business XFNs to deliver key measurement and insights globally. We drive efficiency, instill…
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Project Manager - Global Labeling
Cardinal Health
Springfield, IL
…operational liaison across Regulatory Affairs, Quality, Packaging Engineering, Supply Chain, and Operations to assign deliverables, track progress, and drive cross-functional completion of…
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Design Project Lead, Data Center Design and Construction
Meta
Springfield, IL
…Critical Facilities to become part of our Data Center Design Engineering organization. Our data centers are the foundation upon which our software operates. Building and operating reliable…
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Prin Business Analyst
Exelon
SPRINGFIELD, IL
- $98,400 USD / year
BA/BS in Business, Economics, Political Science, Public Policy or Engineering and 7-10 years related business experience.
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Manager, Regulatory Compliance
Otsuka America Pharmaceutical Inc.
Springfield, IL
Bachelor's degree in life sciences, scientific, or engineering field.
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Sr Customer Success Rep
Honeywell Technologies
Springfield, IL
YOU MUST HAVE
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Site Reliability Engineer
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Chicago, IL
Assist in the use of best-in-class software engineering standards and design practices for instrumenting code/application technology stack to enable the generation of relevant metrics on…
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Clinical AI Strategist - Pharmacist
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Chicago, IL · Riverwoods, IL
…agentic pharmacy solutions. Working alongside the Product and Engineering team, the Clinical AI Strategist translates pharmacist workflows, clinical decision points, drug information needs,…
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Senior Consultant, Industry Solutions, Investment Management
Deloitte
Chicago, IL
AI & Engineering leverages cutting-edge engineering capabilities to build, deploy, and operate integrated/verticalized sector solutions in software, data, AI, network, and hybrid cloud…
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Senior Manager, AI Engineering Platforms
Huntington National Bank
Chicago, IL
Experience with software engineering, platform engineering, DevOps, CI/CD, APIs, and cloud-native architectures
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Senior Air Permitting Specialist
Sargent & Lundy
Chicago, IL
This position is based on a hybrid work schedule and will require in-office work 3 days per week
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Senior Software Engineer (Python, Java, C++, or GoLang) - Chicago, IL- ONSITE 2X Week- FreeWheel
Comcast
Chicago, IL
We are looking for a Sr Software Engineer that will lead the technical design and delivery of complex software solutions. These initiatives will encompass automation, analytics, and cloud…
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Advertising Sales Intern
DIRECTV
Chicago, IL
- $20 to $28 USD / hour
Duration: 10-week hybrid internship (in New York City office 2 days per week) · Eligibility: Must have full U.S
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Architect 2 - Nuclear
Sargent & Lundy
Chicago, IL
Work on challenging assignments with an internationally recognized architectural/engineering firm that includes industrial, commercial and laboratory projects while focusing on power and…

Xenon7

Clinical Data Scientist

Remote, United States

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Job details

Posting language: English
Posted: Oct 21, 2026

Original job description

Description Location: Indianapolis, IN Metro (Hybrid / 3-Day Onsite) (Open to Regional/EST Candidates with Onsite Travel) Contract Type: Contractor Full-Time / Enterprise Project Engagement (Outsourced via Xenon7) About Xenon7 Where elite tech talent meets world-class opportunities! At Xenon7, we work with leading enterprise clients and innovative startups on high-impact projects across Data, AI, Cloud, and Software Engineering. Our expertise in AI solution architecture and specialized technical talent allows us to partner with enterprise leaders on transformative initiatives, driving innovation and business growth.

Role purpose

Lead the development and application of digital twins to improve clinical trial design and support evidence-based clinical development decisions. The role prioritizes digital-twin, simulation, and AI/ML expertise, supported by clinical-development experience and close partnership with trial-design experts.

Position overview You will join a multidisciplinary clinical development environment and partner with clinical scientists, physicians, biostatisticians, pharmacometricians, biomarker experts, data scientists, data engineers, and other stakeholders. You will translate clinical development questions into quantitative strategies and deliver interpretable analyses that inform protocol design, patient selection, endpoint strategy, dosing, operational planning, and decision-making under uncertainty. The role prioritizes digital twins as the primary capability for simulating patients, disease trajectories, treatment response, and clinical trials. The successful candidate will bring strong digital-twin, simulation, and AI/ML expertise, along with sufficient clinical-development knowledge to work effectively with trial teams. Deeper trial-design expertise can be developed through close collaboration with clinical scientists, biostatisticians, and pharmacometricians.

Key responsibilities

Digital-twin development and validation · Lead the design, development, and evaluation of digital twins of patients, disease trajectories, treatment response, or clinical trials using clinical trial and relevant external data. · Combine mechanistic, statistical, causal, and machine learning approaches to create fit-for-purpose digital twins that can be simulated under alternative populations, interventions, dosing strategies, endpoints, or trial designs. · Define use cases and contexts of use with clinical and quantitative experts so each digital twin addresses a specific trial-design or development decision. · Assess calibration, validation, robustness, transportability, uncertainty, and practical relevance using appropriate internal and external evaluation strategies. · Develop reproducible workflows and reusable digital-twin components that can be applied across programs or therapeutic areas. Clinical trial design and quantitative decision support · Partner with trial teams to frame development questions and evaluate design options, including target populations, eligibility criteria, enrichment strategies, comparators, endpoints, visit schedules, dosing strategies, and operational tradeoffs. · Use digital twins and complementary simulation methods to compare plausible scenarios, characterize uncertainty, and support model-informed decision-making. · Work closely with statisticians and pharmacometricians so analyses complement established trial-design methods and align with clinical and regulatory objectives. · Communicate assumptions, limitations, and decision-relevant insights clearly to technical and non-technical stakeholders. Data integration and scientific collaboration · Analyze and integrate clinical trial data and, where relevant, biomarkers, imaging, digital health data, omics, patient-reported outcomes, and real-world data. · Partner with data engineering and platform teams to create analysis-ready datasets, data-quality checks, lineage, and reproducible pipelines. · Contribute to scientific documentation, presentations, publications, and responsible adoption of digital-twin methods across clinical development. Model quality and responsible use · Define the intended use, decision context, success criteria, and limitations of each model before development. · Ensure models are interpretable, auditable, reproducible, and supported by evidence appropriate to their intended use. · Apply appropriate governance, privacy, security, and scientific-review requirements for clinical data and analytical outputs. · Clearly distinguish exploratory analyses from validated decision-support evidence and avoid overclaiming model capability.

· PhD in data science, statistics, biostatistics, pharmacometrics, computer science, biomedical informatics, engineering, mathematics, operations research, or a related quantitative field. · Demonstrated experience developing digital twins, virtual patients, disease-progression models, clinical trial simulations, synthetic controls, or closely related computational models. · Strong experience applying machine learning, statistical modeling, causal inference, or simulation to biomedical, healthcare, pharmaceutical, or other complex scientific data. · Strong programming skills in Python, R, or a comparable analytical language, with experience using version-controlled and reproducible workflows. · Sufficient clinical-development knowledge to frame relevant questions and collaborate effectively with clinical and quantitative trial experts. · Ability and interest to deepen clinical trial-design knowledge through partnership with clinical scientists, biostatisticians, and pharmacometricians. · Strong written and verbal communication skills and demonstrated effectiveness in cross-functional scientific collaboration. Preferred qualifications · Strongly preferred: experience supporting clinical trial design, protocol development, clinical development strategy, model-informed drug development, or regulatory-facing quantitative evidence. · Familiarity with one or more trial-design topics, such as endpoint strategy, sample size or power assumptions, patient selection or enrichment, longitudinal outcomes, missing data, adaptive designs, or decision criteria. · Knowledge of digital-twin architecture and validation, supported by expertise in causal inference, Bayesian modeling, survival analysis, longitudinal modeling, clinical trial simulation, or synthetic controls. · Experience with clinical data standards and common clinical-development data sources. · Experience with biomarker, imaging, omics, digital health, or real-world data and integration of multiple data modalities. · Experience with scalable cloud-based analytical environments. · Track record of translating analytical work into decisions, reusable capabilities, publications, presentations, or other measurable scientific impact.

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Jobs in the United States