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Vertex US Distribution

Manager, Trade Ops

Boston, MA, United States

$112,000 - $168,000

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Job details

Pay: $112,000 - $168,000
Experience: Typically requires 4 years of experience in pharmaceutical/biotech industry or the equivalent combination of education and experience
Posting language: English
Posted: Nov 9, 2026

Original job description

Job Description

General Summary:

The Trade and Distribution Operations Manager provides analytical and operational support to Vertex’s Trade Team and Account Managers. The role combines ex-factory sales, 852/867, specialty pharmacy, invoicing, and 3PL data to develop reports, reconcile invoices, monitor performance, and resolve distribution issues. The manager oversees day-to-day distribution activities and 3PL relationships, including product returns and new product launch planning. This individual contributes to the execution, strategy, and improvement of Vertex’s 3PL program while helping ensure products are available to specialty pharmacy and distributor partners in accordance with Good Distribution Practices (GDP).

Key Duties and Responsibilities:

Develop reports and dashboards for the Trade Team and Account Managers using ex-factory sales, 852/867, specialty pharmacy, invoicing, and 3PL data. Analyze demand, orders, inventory, cost per order, and other performance measures to identify trends and discrepancies.
Support Account Managers with invoice reconciliation, account-level reporting, data requests, and distribution-related questions. Research discrepancies and coordinate resolution with relevant partners.
Execute daily distribution processes, apply trade policies, and triage orders for Vertex’s direct-purchasing accounts.
Serve as the primary contact for 3PL partners. Monitor performance, identify program enhancements, and lead quarterly business reviews, including gathering cross-functional input and preparing performance materials.
Monitor inventory at 3PL and FLW warehouses, track product expiration dates, and coordinate distribution-center transfers and shipment forecasts with Supply Chain and Logistics.
Manage free goods requests by coordinating inventory with program administrators and ensuring timely order processing.
Track program deviations and work with 3PL partners and Vertex Quality on investigations, root-cause analysis, and corrective actions.
Partner with Account Management, specialty pharmacies, distributors, and other teams to resolve shipment discrepancies, damaged product claims, product complaints, and other distribution issues. Support compliant replacement-goods processes, identify process gaps, and implement improvements.
Support new product launches by coordinating with launch teams and channel partners and preparing product setup documentation, external communications, and training materials. Serve as the department’s Mosaic lead for portal maintenance, enhancements, training, and dashboards.

Knowledge and Skills:

Experience working with 3PL providers and managing service-provider relationships.
Strong analytical skills, including the ability to combine ex-factory sales, 852/867, specialty pharmacy, and invoicing data; develop recurring and ad hoc reports; and investigate discrepancies.
Ability to support invoice reconciliation, resolve discrepancies with cross-functional partners, and communicate findings to business stakeholders.
Strong interpersonal and communication skills, with the ability to build credibility and influence diverse field and home-office colleagues, including senior management.
Strong project management and problem-solving skills, with the ability to prioritize competing demands and manage multiple projects in a fast-paced, deadline-driven environment.
Initiative, ownership, and follow-through to work independently, support team members, and foster inclusive, respectful collaboration.

Education and Experience:

Bachelor's degree in a scientific, business or related discipline
Typically requires 4 years of experience in pharmaceutical/biotech industry or the equivalent combination of education and experience

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$112,000 - $168,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

Hybrid: work remotely up to two days per week; or select
On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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More about this job

Skills

Sales
Reporting
Research
Procurement
Supply chain management
Logistics
Root cause analysis
Documentation
Analytical skills
Communication skills
Project management
Problem solving
Motivate employees
Demonstrate curiosity
Decision making

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