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Senior Director, Biomarker and Translational Sciences
Seismic Therapeutic Inc
Watertown, MA
- $220,000 to $280,000 USD / year
…people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that. This is a terrific…
Added 1 hour ago
Data Scientist
District of Columbia Courts
Washington, DC
Added 1 hour ago
Computer Scientist
BOOZ, ALLEN & HAMILTON, INC.
Washington, DC
As an advanced data scientist and researcher on our national security team, you'll evaluate AI methodologies to make a real-world impact on AI usage in strategic intelligence. You'll grow…
Added 3 hours ago
Knowledge Management Subject Matter Expert
CACI International
Charlottesville, VA
CACI is seeking a talented Data Scientist to join our team in Charlottesville, VA. In this role, you will support the Defense Intelligence Agency’s (DIA) Data Science, Analysis, and…
Added 4 hours ago
MSAT Scientist III
ThermoFisher Scientific
Greenville, NC
Complete Technology Transfer activities by performing manufacturing process development for injectable products and transferring them to commercial lines. Using experimental design,…
Added 4 hours ago
MSAT Scientist I
ThermoFisher Scientific
Greenville, NC
Support Technology Transfer activities by performing manufacturing process development for Injectables products to commercial lines. Using experimental design, establish formulation…
Added 5 hours ago
Data Scientists
University of Utah
Salt Lake City, UT
…questions, and make valuable discoveries leading to prototype development and product improvement. Use a flexible, analytical approach to design, develop, and evaluate predictive models and…
Added 6 hours ago
Associate Data Scientist
Steampunk
McLean, VA
We are looking for an Associate Data Scientist to work with our existing team of Data Architects and Developers to develop strategies, create ML/AI solutions, and deliver results. We are…
Added 6 hours ago
FSP Scientist - Formulations, Drug Delivery
ThermoFisher Scientific
South San Francisco, CA
We are seeking a collaborative, curious, and highly motivated Scientist to support parenteral formulation development and drug delivery in the Synthetic Molecule Pharmaceutics group.
Added 6 hours ago
Principal / Sr. Principal Scientist - Molecular Biology & Protein Expression
Lilly
San Diego, CA
The Principal Scientist / Senior Principal Scientist in Molecular Biology & Protein Expression will join a centralized molecular biology and protein expression platform team within Lilly…
Added 6 hours ago
Research Intern (Academic Credit) - Department of Neurology - Per Diem (On-site)
Cedars-Sinai
Los Angeles, CA
…The Research Intern will be immersed in the clinical research process, gaining experience on study design and implementation. The Research Intern will be able to partake in two clinical…
Added 7 hours ago
Business Intelligence Engineer - SCOT, Fulfillment Optimization, SCOT-FO LRN
Amazon
Bellevue, WA
Collaborate with software development teams to implement analytics systems and data structures that support ML model delivery and large-scale experimentation
Added 7 hours ago
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Program Manager, MES
AbbVie
Tempe, AZ
- $109,500 to $208,500 USD / year
Assemble and lead matrixed cross-functional teams comprised of scientist and engineers responsible for all operational aspects of process development, manufacturing, quality assurance and…
Added 8 hours ago
ASST RES SCIENTIST
University of Michigan
Ann Arbor, MI
The assistant research scientist is expected to take a leadership role guiding all laboratory efforts, including planning and implementing experiments, managing staff and laboratory…
Added 8 hours ago
Medical Laboratory Scientist
University of Michigan
Ann Arbor, MI
…education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our…
Added 9 hours ago
Lead Clinical Laboratory Scientist
Veterans Affairs, Veterans Health Administration
Castle Point, NY
Added 9 hours ago
BN
AI Computational Scientist
Brookhaven National Laboratory
UPTON, NY
- $154,250 to $235,000 USD / year
…tools.NSLS-II has initiated AI pilot programs to further the development of these techniques. We are looking to recruit a scientist to work on Ai and machine learning developments…
Added 9 hours ago
University Data Scientist
Booz Allen Hamilton Inc.
ROME, NY
Job Number: R0252610 University - Data ScientistThe Opportunity: As a Data Scientist, you will support analytics projects that help clients make dataadriven decisions. Youall apply…
Added 14 hours ago
Teaching Faculty I
UWMSN University of Wisconsin Madison
Madison, WI
…health counselors. The doctoral degree consistent with the APA's scientist-practitioner model of training, emphasizes the integration of counseling and psychological theory and practice…
Added 17 hours ago
Program Manager, Data Science Core & GenAI Studio
College Board
Remote, United States
…tradeoffs visible. You are not expected to serve as the lead data scientist; you will bring enough technical fluency to understand the data science lifecycle, ask sharp questions, and help…
Added 18 hours ago
S
Research Technician - Bonded Abrasives, R&D
Saint-Gobain
NORTHBORO, MA
- $53,500 to $82,500 USD / year
…team. This role is essential to maintaining execution of key development programs and customer commitments by providing reliable technical support across laboratory and plant environments.…
Added 18 hours ago
Principal Scientist, Translational AI Foundations
Bristol Myers Squibb
Cambridge, MA
…learning - across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. We do this in close partnership with scientific and clinical experts in the…
Added 18 hours ago
Post Doc - AI/ML and Optimization
J&J Family of Companies
Cambridge, MA
J&J Innovative Medicine - Data, Data Science, and AI - Global Development (DDSAI GD) is recruiting a Postdoctoral Scientist - AI/ML and Optimization. The ideal candidate will apply machine…
Added 18 hours ago
Principal Scientist, Statistical Genetics
Bristol Myers Squibb
Cambridge, MA
…driving innovative computational research for discovery and early development within BMS…
Added 22 hours ago
Synthetic DNA Process Development Scientist
Eurofins US Network
Louisville, KY
Synthetic DNA Process Development Scientist Include but are not Limited to the Following:

Vertex Pharmaceuticals Inc (US)

Process Development Engineering Senior Scientist

Boston, MA, United States

$123,200 - $184,800

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Job details

Pay: $123,200 - $184,800
Experience: Willingness to effectively lead a team of scientists/engineers, minimum of 1 year of direct management experience.
Posting language: English
Posted: Oct 29, 2026

Original job description

Job Description

General Summary:

Vertex is seeking a talented individual to join our Process Development team as a Senior Scientist. The primary focus of this role is to lead the execution of process development and engineering studies for a cell-based drug candidate designed to treat diabetes. The Senior Scientist will be responsible for internal process development work, including process robustness and characterization studies, and may support manufacturing investigations. Importantly, the Senior Scientist will lead a weekend shift team to provide continuity for on-going studies over weekends and holidays.

Shift Information: This is a full-time weekend Thursday to Monday 8am to 5pm.

The Process Development group offers a fast-paced and high energy environment. The right candidate will be a subject matter expert in process engineering, or similar relevant field(s) and have a solid technical operations background.

Key Duties and Responsibilities:

Design and execute experimentation to develop robust manufacturing processes for cell therapy products and implementation to support programs in clinical development.
Lead process robustness and characterization studies to support process understanding and clinical development goals.
Lead and train the weekend shift team of bioprocess associates and engineers who will work closely together within a highly matrixed, cross-functional team to deliver program goals.
Communicate effectively to develop reliable weekend coverage plans for ongoing studies, including understanding experimental goals, developing schedules, and delegating the work to the weekend shift team.
Manage and/or execute pluripotent stem cell culture and differentiation to support process development, optimization, and characterization.
Manage troubleshooting with high degree of complexity.
Document experimental procedures and results according to established guidelines. Perform statistical analysis of experimental data to determine critical process parameter ranges.
Communicate progress versus plan, identifying and escalating business-critical issues affecting supply and timelines as necessary, providing recommendations, mitigations, and potential solutions.
Collaborate effectively within departmental teams, contribute to deliverables and drive development activities in a cross-functional environment, engage on team discussions to resolve issues, and lead projects with a fully integrated team to facilitate successful outcomes.
Coordinate resources and set priorities for own team, contributing to the overall goals of the department.
Generate and review technical reports, regulatory filings, source documents, patents and external publications, as applicable.

Knowledge and Skills:

Enthusiastic about maintaining a weekend and holiday shift schedule.
Willingness to effectively lead a team of scientists/engineers, minimum of 1 year of direct management experience.
Strong communicator with experience collaborating on projects and managing changing priorities.
Experience independently conducting and directing the design, execution, analysis, and documentation of cell culture processes for biologics and/or cell therapy products.
Experience in design of experiments (DOE) and statistical analysis.
Pluripotent stem cell culture experience in 2D and/or 3D preferred.
Experience working with cell processing devices and bioreactors such as stirred tank reactors, Unifuge Mini, ATFs, and Ambr250.
Working knowledge of GMP requirements.
Excellent verbal and written communication skills and ability to handle multiple tasks while meeting timelines and adapting to changing priorities.
Strong organizational skills and high attention to detail.

Education and Experience:

BS in Biochemistry, Engineering, Biology or related discipline with 8+ years of industry experience; or an MS with 5+ years of industry experience; or a PhD with 2-5 years of industry experience.

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$123,200 - $184,800

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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More about this job

Skills

Process engineering
Manufacturing processes
Stem cells
Troubleshooting
Statistics
Lead a team
Documentation
Good manufacturing practices
Communication skills
Organizational skills
Attention to detail
Motivate employees
Demonstrate curiosity
Decision making

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