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Added 1 min ago
C
Senior Project Manager – Transit Permitting Strategy
Cordoba
Seattle, WA
- $145,000 to $225,000 USD / year
Permit and Regulatory Process Leadership This position will play a key role in improving transportation project delivery by strengthening permitting, regulatory coordination, and agency…
Added 1 min ago
PE
Project Manager
Pivot Energy
Denver, CO · Chicago, IL
- $100,000 to $140,000 USD / year
The Project Manager supports Pivot Energy’s owner-side project delivery function from formal handoff out of preconstruction and contract readiness through engineering, procurement,…
Added 3 mins ago
Senior Project Manager, Project & Development Services
Cushman & Wakefield U.S., Inc.
Charlotte, NC
Must have exceptional organizational, analytical and problem-solving · Must have the ability to lead a team and/or mentor less experienced team members
Added 3 mins ago
Assistant Facilities Manager
Cushman & Wakefield U.S., Inc.
Coppell, TX
Certified Facility Manager (CFM), International Facilities Management Association (IFMA), Building Owners and Managers Association (BOMA) industry certifications recommended; other…
Added 3 mins ago
Senior Project Manager
Cushman & Wakefield U.S., Inc.
Remote, United States
The Senior Project Manager provides project management experience to designated projects and assignments for a particular client account, property portfolio, or large facility/complex…
Added 3 mins ago
Sr. Project Manager
Cushman & Wakefield U.S., Inc.
Remote, United States
The Senior Project Manager provides project management experience to designated projects and assignments for a particular client account, property portfolio, or large facility/complex…
Added 5 mins ago
IC
Senior Civil Engineer Water System Planning
Innovation Consulting
Irvine, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
Added 5 mins ago
IC
Senior Civil Engineer Water System Planning
Innovation Consulting
Philadelphia, PA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
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IC
Senior Civil Engineer Water System Planning
Innovation Consulting
Riverside, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
Added 5 mins ago
IC
Senior Civil Engineer Water System Planning
Innovation Consulting
San Diego, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
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IC
Senior Civil Engineer Water System Planning
Innovation Consulting
Oakland, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
Added 5 mins ago
IC
Senior Civil Engineer Water System Planning
Innovation Consulting
San Francisco, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
Added 5 mins ago
IC
Senior Civil Engineer Water System Planning
Innovation Consulting
Bakersfield, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
Added 5 mins ago
IC
Senior Civil Engineer Water System Planning
Innovation Consulting
Fresno, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
Added 5 mins ago
IC
Senior Civil Engineer Water System Planning
Innovation Consulting
San Jose, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
Added 5 mins ago
IC
Senior Civil Engineer Water System Planning
Innovation Consulting
Sacramento, CA
- $113,000 to $177,000 USD / year
…Utilities Commission. The role reports to the Capital Planning…
Added 5 mins ago
Director Technical Product Management - Data Platform
E2E Alignment Healthcare USA, LLC
Remote, United States
…data, combining technical credibility across data architecture, engineering, and governance with the product discipline to turn business priorities into measurable platform outcomes. The…
Added 6 mins ago
CNC Lead
Express Employment Professionals
Yorba Linda, CA
Escalate significant equipment, tooling, programming, or process concerns to the CNC supervisor, Production Manager, Engineering, or Quality as appropriate.
Added 6 mins ago
BI Developer
Emeryville, CA
…work in Power BI and SQL, while partnering closely with Data Engineering and working within a broader modern data ecosystem that includes Snowflake and…
Added 9 mins ago
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Game Systems Designer
The Pokémon Company International
Bellevue, WA
- $86,000 to $150,000 USD / year
…collaborate with cross-functional teams including UX/UI Designers, Engineering, and Game Producers to implement, maintain, and improve game systems and content. This role will focus on…
Added 11 mins ago
Maintenance Supervisor - Weekend AM
WTL Wheatland Tube, LLC
Rochelle, IL
Reporting to the Department Manager, this hands-on Maintenance Supervisor will oversee the maintenance team. This role is responsible for ensuring the reliability, efficiency, and safety of…
Added 11 mins ago
Manager, Strategic Account Management
DoorDash USA
Denver, CO · Phoenix, AZ
We're looking for a Manager, Outside Account Management to lead and develop a team of Strategic Partner Managers, while achieving our regional goals of growing the merchant side of the…
Added 11 mins ago
Software Engineer I, Payments
Twitch
San Francisco, CA
As a key member of the engineering team, you will report to the Senior Engineering Manager of Payments team and have the opportunity to build and scale solutions that affect millions of…
Added 11 mins ago
T&
Associate Director Project Manager - Retail Construction
Turner & Townsend
Los Angeles, CA
- $115,000 to $125,000 USD / year
Bachelor’s degree in construction management, architecture, engineering or field related to construction.
Added 13 mins ago
CI
Assistant Project Manager
Classic Industrial Services, Inc.
Baltimore, MD
- $29 to $41 USD / hour
…We are currently seeking candidates for an Assistant Project Manager (APM) to join the team in our Baltimore office. The APM works closely with the Project Manager to ensure projects are…

Vertex Pharmaceuticals Inc (US)

Process Development Engineering Senior Scientific Associate

Boston, MA, United States

$73,900 - $110,900

Apply on vrtx.wd501.myworkdayjobs.com About employer

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Job details

Pay: $73,900 - $110,900
Posting language: English
Posted: Nov 13, 2026

Original job description

Job Description

General Summary:

Vertex is seeking a lab-based Senior Scientific Associate to provide engineering and operational expertise within Upstream Process Development Engineering. This individual contributor will support T1D programs through high-throughput and bench-scale bioreactor studies, with particular emphasis on ambr250 operations, small-scale model development, stirred-tank reactor (STR) process robustness, and process characterization. The role will plan and execute studies, solve complex equipment and process issues, coordinate materials and laboratory activities, and translate experimental data into clear technical conclusions. The successful candidate will serve as a technical resource for ambr250 and bioreactor operations and will partner across Process Development, Research, Analytical Development, Manufacturing, and other functions to align best practices, improve platform reliability, and establish consistent approaches across teams and sites.

Key Duties and Responsibilities:

Plans, coordinates, executes, and documents upstream process-development studies using ambr250 and bench-scale bioreactor platforms in support of STR scale-up, process robustness, and process characterization.
Provides hands-on technical expertise for ambr250 operation, including system setup, method development, study execution, maintenance, troubleshooting, and continuous improvement of operating practices.
Develops, evaluates, and improves ambr250 scale-down models, including assessment of model representativeness, operating ranges, comparability to larger-scale STR processes, and sources of variability.
Applies bioreactor engineering and control principles to troubleshoot complex process and equipment issues related to mixing, mass transfer, gas delivery, pH and dissolved oxygen control, feeding, sampling, and data acquisition.
Provides advanced troubleshooting support for bench-scale bioreactor platforms, including Ascent and PBS systems, and helps determine root cause, corrective actions, and appropriate escalation pathways.
Owns study design, material planning, scheduling, and coordination of laboratory resources to enable successful and timely execution of time-sensitive experiments.
Uses JMP and other appropriate tools for experimental design, multivariate analysis, modeling, data visualization, data interpretation, and assessment of process comparability.
Prepares study protocols, electronic records, data summaries, technical reports, and presentations that clearly communicate methods, results, conclusions, risks, and recommended next steps.
Partners with colleagues across Process Development and cross-functionally to align ambr and bioreactor best practices, standardize workflows, share lessons learned, and improve operational consistency.
Serves as a technical owner or super user for key laboratory equipment, including Cedex cell-counting systems, and provides advanced troubleshooting, maintenance coordination, user guidance, and readiness support.
Identifies opportunities to improve laboratory workflows, equipment utilization, data quality, automation, and process understanding; leads or supports implementation of practical solutions.
Contributes technical input to project planning and risk assessment and proactively communicates issues that may affect study quality, timelines, or program decisions.
Mentors and trains colleagues in ambr250 operations, bioreactor fundamentals, equipment troubleshooting, JMP analysis, and effective study execution.
May participate in weekend or off-hours laboratory coverage when needed to support critical cell-culture and bioreactor operations.

Knowledge and Skills:

Demonstrated hands-on expertise with ambr250 or a comparable high-throughput bioreactor platform, including independent operation, troubleshooting, and study execution.
Strong understanding of mammalian or stem-cell culture and aseptic processing in a process-development laboratory environment.
Strong knowledge of bioreactor control principles and their application to scale-down models, bench-scale studies, and STR scale-up.
Ability to diagnose complex process, equipment, and workflow issues using data, engineering fundamentals, structured problem solving, and sound technical judgment.
Experience developing or qualifying small-scale models and evaluating scale relevance, comparability, operating ranges, and model limitations.
Proficiency with JMP for design of experiments, statistical modeling, multivariate analysis, data visualization, and interpretation; ability to coach others in appropriate application of these tools.
Experience operating and troubleshooting cell-counting and analytical equipment; Cedex expertise is strongly preferred.
Ability to manage study design, materials, schedules, documentation, and cross-functional dependencies with limited supervision.
Strong technical writing and communication skills, including the ability to translate complex data into concise conclusions and recommendations.
Demonstrated collaboration across teams or sites and a consistent focus on shared best practices, operational excellence, quality, safety, and data integrity.

Education and Experience:

Bachelor’s degree in Chemical Engineering, Biochemical Engineering, Biomedical Engineering, Biotechnology, Biology, or a related scientific or engineering discipline with 3+ years of relevant experience; or a Master’s degree with 1+ years of relevant experience; or an equivalent combination of education and experience.
Relevant experience should include mammalian or stem-cell culture, high-throughput or bench-scale bioreactor operation, and execution of process-development studies.
Direct experience with ambr250, process scale-down model development, bioreactor troubleshooting, Cedex systems, and JMP-based experimental design or modeling is strongly preferred.
Experience supporting cell-therapy, regenerative-medicine, or other complex biologics process development is preferred.

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$73,900 - $110,900

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Apply on vrtx.wd501.myworkdayjobs.com About employer

More about this job

Skills

Research
Troubleshooting
Process improvement
Troubleshoot
Scheduling
Data visualization
Presentation skills
Laboratory equipment
Hazard assessment
Stem cells
Workflow
Problem solving
Documentation
Technical writing
Communication skills
Collaboration
Chemical engineering
Biomedical engineering
Biotechnology
Motivate employees
Demonstrate curiosity
Decision making

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Work requirements

Jobs in the United States