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Vertex Pharmaceuticals Inc (US)

Analytical Development Research Scientist

Boston, MA, United States

$102,800 - $154,200

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Job details

Pay: $102,800 - $154,200
Posting language: English
Posted: Nov 9, 2026

Original job description

Job Description

General Summary:

The Analytical Development Research Scientist works with a high degree of independence and is adept at designing and executing complex experimental procedures within required timelines. Completes work in a resourceful, self-sufﬁcient manner and is able to troubleshoot and design alternative approaches to achieve desired outcomes. Performs strategic planning consistent with regulatory guidance, implements innovative approaches and maintains a high level of technical knowledge. Authors and reviews method documents, analytical study protocols and reports. Works collaboratively within the analytical development team and cross-functionally with other groups to meet CMC organizational goals. This is a hands-on role combining advanced data analytics with laboratory-based assay development in a cross-functional setting.

Key Duties and Responsibilities:

Independently conceptualize, develop, and deploy analytical solutions that support characterization of cell-based products
Perform laboratory experiments supporting analytical method development for gene and cell therapy products, and apply statistical analyses to assess specificity, sensitivity, linear range, precision, and accuracy
Analyze complex experimental and process data, and create clear visualizations and present findings and recommendations to technical teams and management
Execute test methods supporting Process Development activities to support process improvements
Author and review SOPs, protocols, technical reports, and transfer and qualification documentation, and contribute analytical content to regulatory filings
Maintain clear, accurate, and compliant records, including electronic lab notebooks and test forms
Stay current with developments in the broader data science community and apply relevant approaches to analytical challenges

Knowledge and Skills:

Demonstrated experience applying data science and statistical analysis to complex scientific questions
Ability to independently plan and execute technical work, interpret results, and communicate conclusions to cross-functional audiences
Advanced data analysis, statistical analysis (e.g. JMP, GraphPad Prism, PLA analysis), data visualization, machine learning, and modeling proficiency
Strong skills in analytical programming (Python, R, SQL, cloud platforms)
Hands-on experience with at least one of the following: cell count & viability, cell cluster characterization, flow cytometry, mammalian cell culture
Assay development, qualification, troubleshooting, optimization, and performance trending
Characterization and release testing for identity, purity, strength, and potency
Clear and effective communication abilities
Independent project leadership
Ethical data practice adherence
Experience with ELN/LIMS systems
SOP, protocol, and technical report authoring
Knowledge around regulatory guidance for cell therapy and cell-based assay development from FDA, ICH, and USP

Education and Experience:

Ph.D. (or equivalent degree) and 0-3 years of relevant post-doctoral employment experience, or
Masters Degree (or equivalent degree) and 3+ years of relevant employment experience, or
Bachelors Degree (or equivalent degree) and 6+ years of relevant employment experience
Experience in an analytical development program, providing technical support in a manufacturing setting or technical role in a QC environment
Experience designing and/or performing assay qualification, including authoring and/or reviewing relevant documentation

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$102,800 - $154,200

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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More about this job

Skills

Research
Troubleshoot
Strategic planning
Manage quantitative data
Documentation
Statistics
Data analysis
Data visualization
Machine learning
Python
R
SQL
Troubleshooting
Communication skills
Leadership
LIMS
Technical support
Motivate employees
Demonstrate curiosity
Decision making

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