Jobs in the United States

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Added 13 mins ago
M
Senior Software Engineer - CoreAI
Microsoft
WA · Redmond, WA · Redmond
- $119,800 to $261,000 USD / year
App Service is a Platform as a Service (PaaS) offering and one of the top services in Azure all-up. As a Senior Software Engineer - CoreAI, you will have a chance to work on the largest…
Added 13 mins ago
M
Software Engineer 2 - CoreAI
Microsoft
WA · Redmond, WA · Redmond
- $102,100 to $219,200 USD / year
The Cloud App and Tools team in CoreAI is looking for a Software Engineer 2 - CoreAI to help us build the next generation of Azure libraries and developer tooling. Our missi
Added 14 mins ago
M
Principal Software Engineer - AI Experiences, Monetization
Microsoft
WA · CA · Redmond, WA · Mountain View, CA · Redmond · Mountain View
- $142,800 to $304,200 USD / year
…applications customers use every day? Want to use AI to change how software is built and delivered? If so, we'd love to hear from…
Added 14 mins ago
M
Principal Software Engineer - Microsoft Advertising
Microsoft
WA · Redmond, WA · Redmond
- $142,800 to $304,200 USD / year
This Principal Software Engineer role owns core architectural and technical evolution of the platform, focusing on modernization, performance, scalability, experimentation infrastruc
Added 14 mins ago
M
Principal Software Engineer-M365
Microsoft
WA · CA · Redmond, WA · Mountain View, CA · Redmond · Mountain View
- $142,800 to $304,200 USD / year
Added 14 mins ago
M
Software Engineer II
Microsoft
WA · CA · NY · Redmond, WA · Mountain View, CA · Redmond · Mountain View · New York
- $102,100 to $219,200 USD / year
We are looking for a Software Engineer II to join the Special Projects and Resources Team (SPARTANs) in M365 Core – Substrate. SPARTANs take on strategic projects and difficult engineering…
Added 16 mins ago
M
Software Engineer - CTJ - Top Secret
Microsoft
VA · Reston, VA · Reston
- $85,400 to $183,700 USD / year
Are you interested in building and securing cloud‑scale software that protects some of the world’s most sensitive and mission‑critical environments? As a Software Engineer in Microsoft’s…
Added 16 mins ago
M
Principal Software Engineer
Microsoft
United States
- $142,800 to $304,200 USD / year
Added 16 mins ago
M
Senior Software Engineer
Microsoft
WA · Redmond, WA · Redmond
- $119,800 to $261,000 USD / year
Added 16 mins ago
M
Principal Software Engineer
Microsoft
WA · Redmond, WA · Redmond
- $142,800 to $304,200 USD / year
…Engagement and Engineering Direct Team is seeking a Principal Software Engineer to own the architecture for secure, enterprise-scale platforms spanning supportability, customer-centric…
Added 16 mins ago
M
Senior Software Engineer, Foundry IQ - CoreAI
Microsoft
WA · CA · Redmond, WA · Mountain View, CA · Redmond · Mountain View
- $119,800 to $261,000 USD / year
As a Senior Software Engineer, you will build infrastructure that protects customer data and keeps search
Added 29 mins ago
C++ Software Engineer, Junior
BOOZ ALLEN HAMILTON INC
Dayton, OH
Job Number: R0251725 C++ Software Engineer, Junior The Opportunity: Develop solution architecture (SA) and resolve complex issues in a variety of projects through the implementation of…
Added 30 mins ago
Software Engineer II
Ampcus Incorporated
Cincinnati, OH
…highly motivated candidate to join our talented Team. Job Title: Software Engineer - II/ .Net Developer Location: Atlanta, GA 30326 or Oklahoma City, OK 73132, or Cincinnati, OH 45249 - 3…
Added 30 mins ago
Software Engineer / Architect
DCS CORPORATION
Dayton, OH
Job Brief Software Engineer / Architect Infoscitex (IST), a DCS company, has an opportunity for an outstanding Software Engineer / Architect to join our team to support an extensive…
Added 36 mins ago
Senior Software Engineer, DevOps
Atria Health and Research Institute
NY · New York, NY
Added 36 mins ago
Senior Software Engineer, DevOps
Atria Health and Research Institute
Remote, United States
Added 36 mins ago
Software Engineer, DevOps
Atria Health and Research Institute
NY · New York, NY
Added 36 mins ago
Software Engineer, DevOps
Atria Health and Research Institute
Remote, United States
Added 36 mins ago
Software Engineer, Product
Atria Health and Research Institute
Remote, United States
Added 36 mins ago
Software Engineer, Product
Atria Health and Research Institute
Remote, United States
Added 36 mins ago
Staff Software Engineer, Foundations
Atria Health and Research Institute
Remote, United States
Added 36 mins ago
Staff Software Engineer, Foundations
Atria Health and Research Institute
Remote, United States
Added 39 mins ago
Rendezvous and Proximity Operations Oversight Software Engineer
Amentum
Houston, TX
Added 51 mins ago
AT
Machine Learning Senior Software Engineer
Akamai Technologies, Inc.
Jefferson City, MO
- $121,400 to $218,600 USD / year
Added 57 mins ago
A&
Cloud Architect
Astor & Sanders
Remote, United States
- $130,000 to $155,000 USD / year

Tempus AI, Inc.

Senior Software Engineer

United States

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Job details

Experience: 7+ years of software development experience with a track record of technical leadership.
Posting language: English
Posted: Nov 3, 2026

Original job description

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Join the Revolution in Precision Medicine: At Tempus, we're leveraging cutting-edge technology to transform healthcare through AI-powered insights. Our proprietary platform connects real-world evidence to deliver actionable intelligence to physicians, ensuring the right treatments reach the right patients at precisely the right time.

Our Engineering Culture: We operate in small, autonomous teams where developers, designers, scientists, and product managers collaborate closely. You'll have direct ownership in building solutions that make a meaningful impact in cancer research and treatment. Our agile approach and modern architecture enable us to innovate rapidly while maintaining the highest standards of quality and scalability.

About the Role: We are seeking a highly motivated and capable Senior Software Engineer to help advance our Genomics AI initiatives. In this role, you will lead the analysis and design of complex technical problems, architect robust systems, and mentor emerging talent. This position requires deep expertise in full-stack engineering, relational data systems, and algorithmic development. As a senior technical leader, you will be expected to craft high-quality code while leveraging modern AI tooling, integrating Generative AI APIs into user-facing applications, and embedding agentic workflows into our core product ecosystem.

Technical Requirements

5+ years of advanced TypeScript/JavaScript development with deep understanding of language features and optimization techniques.
Extensive experience architecting and leading development with Node.js and NestJS frameworks.
Expert-level React development with demonstrated ability to design and implement complex component systems.
Hands-on experience leveraging GenAI coding tools and autonomous agents (e.g., Copilot, Cursor, LLM APIs) to accelerate development, refactor codebases, and auto-generate comprehensive unit/integration tests.
Experience or strong working knowledge of integrating LLM APIs and GenAI technologies into production applications.
Advanced PostgreSQL skills including query optimization, indexing strategies, and performance tuning.
Proven expertise implementing sophisticated Redis caching solutions for high-throughput systems.
Demonstrated success designing and implementing distributed microservice architectures.
Significant experience orchestrating infrastructure and applications on GCP, including CI/CD pipelines.
Mastery of enterprise-level design patterns and their practical application in large-scale, mission-critical systems.

What Makes You a Great Fit

7+ years of software development experience with a track record of technical leadership.
Ability to make high-impact architectural decisions that balance business needs with technical considerations.
Enthusiasm for championing AI-assisted development practices, driving adoption of agentic workflows, and mentoring teams through the evolving landscape of AI tools.
History of successfully delivering complex projects in fast-paced environments.
Strong communication skills with experience presenting technical solutions to diverse stakeholders.
Proven ability to drive cross-team technical initiatives and resolve complex engineering challenges.

Bonus Points

Experience with search technologies such as Elasticsearch or OpenSearch.
Experience with containerization orchestration (Docker, Kubernetes).
Background in biotech, genomics, or precision medicine.
Success leading system migrations between cloud platforms (e.g., AWS to GCP).

CHI: $110,000-$160,000

The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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More about this job

Skills

Research
TypeScript
JavaScript
Node.js
React
PostgreSQL
Redis
Google Cloud
CI/CD
Software development
Leadership
Communication skills
Elasticsearch
Docker
Kubernetes
AWS

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