Jobs in the United States

25+ jobs

Save this search

Added just now
Project Engineer - Land Development
Atwell, LLC
Dallas, TX · Fort Worth, TX
Guide and mentor engineers and CAD technicians.
Added 1 min ago
Senior CAD Designer
Steelcase Inc.
Grand Rapids, MI
…your ideas become reality? If you are, we're hiring a Senior CAD Designer to perform complex mechanical design tasks, improve product designs and work collaboratively with various…
Added 4 mins ago
Senior CNC 5-Axis Mill Machinist, Prototype Shop
Varda Space Industries
El Segundo, CA
…ensuring transparent communication through digital work orders, CAD/CAM notes, and direct…
Added 11 mins ago
Manufacturing Engineer II
Lennox International
Stone Mountain, GA
Knowledge of design techniques, tools, and principles involved in production of precision technical plans, blueprints, drawings, and models.
Added 12 mins ago
Project Engineer
Malibu Electronics, LLC
Lenoir City, TN
The Project Engineer is responsible for creating, maintaining, revising, and managing production and prototype harness CAD drawings and associated engineering documentation to support…
Added 18 mins ago
Design Engineer III
Amphenol Interconnect Products
Endwell, NY
Minimum of 5-7 years’ experience with modeling tools (CAD, Pro E, or Solidworks) and Microsoft Office products.
Added 20 mins ago
Project Manager - Water & Wastewater
French & Parrello
Wall Township, NJ
Familiarity and experience with MS Office 365, computer-aided design tools and software including Autodesk’s AutoCAD and Revit (BIM) and Esri’s ArcGIS. Experience with Bentley’s hydraulics…
Added 21 mins ago
Technical Lead - Plant Equipment Design
GE Vernova Hitachi Nuclear Energy Americas LLC
Remote, United States
…installation through commissioning as well as stewardship of guides, tools, skill development, knowledge capture, lessons learned, best practices, issue resolution, and supplier or partner…
Added 21 mins ago
Technical Leader - Plant Equipment Design
GE Vernova Hitachi Nuclear Energy Americas LLC
Remote, United States
…installation through commissioning as well as stewardship of guides, tools, skill development, knowledge capture, lessons learned, best practices, issue resolution, and supplier or partner…
Added 26 mins ago
CNC Machinist
KOCH INDUSTRIES INC
MENOMONIE, WI
Added 26 mins ago
Sr. Product Engineer
Atkore
Harvey, IL · Merrillville, IN
Strong CAD capability; experience with Autodesk tools, SolidWorks, AutoCAD, Vault, Fusion, or similar design/PDM platforms preferred.
Added 28 mins ago
Lead Manufacturing Engineer
Aptiv
Garden Grove, CA
Systems Proficiency: Proficiency in 2D/3D CAD software (e.g., SolidWorks, AutoCAD) and ERP/MRP systems; Syspro experience is a plus. Systems used: Google Workspace, SmartView, Salesforce,…
Added 28 mins ago
Sr Mgr Police Communications - Fort Worth, TX
BNSF
Fort Worth, TX
Oversee Technology and Systems Management: Manage and coordinate the use of communications technology, including CAD (Computer-Aided Dispatch), radio systems, card access, camera…
Added 34 mins ago
Product Engineer (On-Site)
DMA Industries, LLC
Marion, SC
Utilize 2D/3D CAD software and 3D scanning tools for design, comparison, and optimization of parts.
Added 35 mins ago
Business R&D Experienced Professional
Hitachi Global
Alamo, TN
Strong proficiency in 3D CAD design tools, with Creo experience highly valued.
Added 37 mins ago
Sr Advanced Hardware Engineer
Aerospace
Clearwater, FL
Experience with other CAD software (CREO, NX) and design tools
Added 38 mins ago
G
Electrical Design Engineer
GPAC
Hot Springs, AR
- $80,000 to $110,000 USD / year
Software Skills: Proficiency with industry-standard CAD software (e.g., AutoCAD Electrical, Altium Designer, OrCAD, or SolidWorks Electrical).
Added 39 mins ago
Key Account Manager, Midwest
Axis Communications Inc
Remote, United States
Writes and maintains all documentation related to the account. Including meeting minutes, notes, designs, Axis CRM, tracking tools.
Added 41 mins ago
Sr. PLM Architect
Pentair
Apex, NC
…design approach that avoids custom modifications to ERP or CAD…
Added 41 mins ago
Project Engineer - Land Development
Atwell, LLC
Madison, WI
Guide and mentor engineers and CAD technicians.
Added 41 mins ago
Project Engineer
MBI - Malibu Boats, Inc
Lenoir City, TN
The Project Engineer is responsible for creating, maintaining, revising, and managing production and prototype harness CAD drawings and associated engineering documentation to support…
Added 44 mins ago
Tool & Die Technician
IDEX
Oklahoma City, OK
…engineering, and continuous improvement initiatives by fabricating new tools, fixturing, modifying existing components, and ensuring tooling meets safety, quality, and performance…
Added 45 mins ago
PL
Project Engineer (Manufacturing)
ProCaps Labs
Broomfield, CO
- $140,000 to $145,000 USD / year
Develop a detailed project plan to monitor and track progress (Gantt Chart/Cad Drawings/Cost)
Added 45 mins ago
Manufacturing Engineer II
CMD CORPORATION
Appleton, WI
Proficient in manufacturing fundamentals and tools (CAD, ERP, CI, Six Sigma).
Added 46 mins ago
G
Electrical Design Engineer
GPAC
Clinton, AR
- $80,000 to $110,000 USD / year
Software Skills: Proficiency with industry-standard CAD software (e.g., AutoCAD Electrical, Altium Designer, OrCAD, or SolidWorks Electrical).

Sirtex

Principal Product Development Engineer

Woburn, MA, United States

$150,553 to $175,000 USD / year

Apply About employer

Applications open in a new tab.

Job details

Pay: $150,553 to $175,000 USD / year
Experience: BS degree in Biomedical, Mechanical or a related engineering discipline with 12+ years of medical device product development experience, or a MS with 10+ years.
Posting language: English
Posted: Nov 6, 2026

Original job description

Company Description Sirtex Medical is a global leader in healthcare, with offices in the U.S., Australia, Germany, and Singapore, dedicated to improving patient outcomes. Our mission is to be at the forefront of minimally invasive cancer and embolization therapies. By partnering with physicians, we aim to provide innovative products that enhance patient outcomes and simplify treatments. Achieving this ambitious goal requires passionate and talented individuals who are committed to making a difference. Our flagship product, SIR-Spheres® Y-90 resin microspheres, is a targeted radiation therapy for liver cancer. To date, we have delivered over >150K doses across 50+ countries, significantly impacting patients' lives worldwide. Our success is fueled by our dedication to serving the medical community, maintaining professionalism, fostering a collaborative work culture, nurturing an entrepreneurial spirit, and continuously pursuing innovation and improvement. At Sirtex, we are committed to creating a great workplace. We offer a range of benefits, programs, and services to support our employees, ensuring they have opportunities to contribute to our success and advance their careers. Join our inclusive community, where you can collaborate with talented colleagues, bring your ideas to life, and advance your career, all while delivering innovative healthcare solutions to patients.

Job Description

About the role Sirtex Medical is hiring a Principal Product Development Engineer to serve as the senior individual-contributor technical authority. You will provide project leadership, own the technical integrity of design controls, verification, validation and regulatory submissions from concept through commercialization and sustaining. This is a hands-on leadership role. You will set technical direction for cross-functional teams, write and defend the evidence that gets products approved and keeps them on the market, and mentor engineers who will grow into the next generation of technical leads. Candidates must be local to the Boston, MA area and be willing to adhere to our hybrid work arrangements, currently 3 days/week in office and 2 days/week remote. Location: Woburn, MA - hybrid/on-site

Key responsibilities

Serve as project lead on one or more concurrent development programs, from user needs and design inputs through design transfer and commercial launch
Collaborate closely with Quality, Manufacturing, Regulatory and Marketing
Own Design History File content and lead formal design reviews, ensuring traceability from user needs to verification and validation evidence
Drive concept generation and feasibility work and protect resulting innovations through invention disclosures and patent filings
Engage marketing team and clinicians to define user needs and translate them into testable requirements
Lead and own Design Verification
Work in partnership with manufacturing and design quality to support transfer to manufacturing / Process Validation (IQ/OQ/PQ)
Manage external labs for testing including testing plan development, reports and assess the impact of design, material and supplier changes
Act as a subject matter expert for biological safety and provide strategy
Lead R&D modules of FDA submissions (PMA, PMA supplements, IDE, 510(k)) and EU MDR Technical Documentation, and respond to Regulatory and Notified Body questions
Partner with Quality on design risk management per ISO 14971, owning the engineering inputs to DFMEA/PFMEA and benefit-risk analysis
Participate in complaint investigations, root cause analysis and CAPA, and support FDA inspections and audits when needed
Partner with Quality and Manufacturing on product and process improvements
Mentor and develop engineers, including technical reviews of their protocols, reports and design decisions
Champion continuous improvement in engineering efficiency

Qualifications

BS degree in Biomedical, Mechanical or a related engineering discipline with 12+ years of medical device product development experience, or a MS with 10+ years.
Demonstrated technical leadership of Class II and/or Class III PMA devices through design controls, design transfer and commercial launch required
Hands-on authorship of Design Verification, Test Method Validation and Process Validation (IQ/OQ/PQ) protocols and reports
Working command of 21 CFR 820 / QMSR, ISO 13485, ISO 14971 and ISO 10993
Clear, concise technical writing, and the ability to explain risk and trade-offs to executive leadership and non-engineering audiences
Experience in leading the R&D module in FDA PMA, IDE or 510(k) submissions
Experience leading root cause investigations, complaint handling and CAPA
Basic proficiency with 3D CAD tools (e.g., SolidWorks) and statistical analysis tools (e.g., Minitab, JMP) required
Hands-on experience with IEC 62366-1 and FDA HFE guidance including use-related risk analysis, formative studies, critical task identification, and summative (HF validation) testing and reporting will be a plus
Formal training in statistical problem-solving (such as Six Sigma) preferred
Track record managing or mentoring engineers, co-ops or interns
Experience in a growth-stage or startup environment, where wearing multiple hats was the norm

The target anticipated annual base salary range and target bonus opportunity is $150,553 to $175,000 annually, plus a 15% target annual bonus of 15% The final position level and compensation will be determined based on non-discriminatory, job-related factors, including geographic location, skills, experience, education, and alignment with the position requirements. In addition to base salary and bonus eligibility, Sirtex offers a comprehensive benefits package, including paid sick and vacation time, medical, dental, vision and life insurance, and a generous 401(k) matching program and other benefits, subject to applicable plan terms and eligibility requirements. Additional Information All your information will be kept confidential according to EEO guidelines

Do you want to be part of something bigger? A team whose impact stretches across the globe making a real difference to the quality of people’s lives. Sirtex recognizes that well-being, financial health, and work-life balance are crucial for our employees to achieve personal success.

Sirtex offers qualified candidates:

Diverse and flexible work arrangements to achieve the optimum balance between work and personal responsibilities.
A culture of respect, diversity, collaboration, and innovation fostering inclusiveness and superior performance.
Attractive compensation and benefit packages which are practical, robust and equitable.
A commitment to support ongoing professional growth through career development, on the job experiences and training opportunities.
Challenging work which supports the development of new and better ways to improve clinical outcomes for oncology treatment around the world.
An unwavering commitment to company values, employee safety and excellence in everything we do.

Diversity drives innovation; inclusion fosters belonging, growth and success. Sirtex believes that it takes multiple perspectives and voices to create a culture and workplace which fosters engagement, teamwork, and employee satisfaction to perform our best and deliver on commitments. We are dedicated to fostering an environment where all employees feel valued, included, and can share their ideas so that we can exceed even our own expectations. Sirtex is An Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age or any other characteristic protected under applicable law. Sirtex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Apply About employer

Report this job