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Program Manager, RES (Risk Engineering Solutions)
CBRE
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- $105,000 to $125,000 USD / year
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Product Manager, Team Digital Products
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Added 10 mins ago
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Senior Tax Manager
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- $140,000 to $165,000 USD / year
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Bilingual HR Manager
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- $48.08 to $57.7 USD / hour
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Clinical Research Associate II - West or Pacific Northwest US - FSP
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Senior ALC Developer PART TIME
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Data Science Specialist
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Added 19 mins ago
C
Program Manager, RES (Risk Engineering Solutions)
CBRE
Saint Paul, MN
- $105,000 to $125,000 USD / year
The Program Manager will partner with RES, DRI, and BD&Ecustomer and stakeholder teams to verify and track business needs, drivecross-functional collaboration, manage program reporting,…

Seqirus Inc

Operational Excellence Lead

Seqirus USA, NC, United States

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Job details

Experience: Minimum of 6 years of relevant Operational Excellence experience, with a proven track record in:
Posting language: English
Posted: Nov 4, 2026

Original job description

The Opportunity:

As the Operational Excellence (OE) Manager, you will play a key role in driving performance improvement, implementing and further developing the new CSL Operating System (COS) at CSL Seqirus’ manufacturing site in Holly Springs, NC. COS, grounded in Lean principles, aims to standardize processes across the site(s), foster a performance-driven culture, and accelerate business performance.

You will serve as a subject matter expert in Lean shop floor management (e.g. develop Process Centric Teams, Visual Management, Standard Work, Leader Standard Work, Continuous Improvement), facilitating transformational change and leading initiatives that embed COS methodologies into everyday operations.

You will articulate and implement the OE Vision (Where we are going), Purpose (Why we are doing it), Mission (How we will achieve it), and Goals (What we aim to accomplish) for the site, ensuring alignment across all organizational levels. Additionally, you may contribute to global initiatives but travel would be very rare.

This role offers the opportunity to work in a matrixed environment, influencing not only local teams but also contributing at a network level through the CSL OE Community of Practice. You will lead, coach, and mentor teams across multiple layers of the organization, ensuring the COS mindset and practices are embraced at every level and help achieving the site(s) Compelling Business Needs (CBNs).

The Role:

Operational Excellence Leadership:

Serve as an OE Business Partner, leading and coaching COS rollouts in both operational and support areas
Develop, implement, and further develop the OE roadmap for a key value stream and/or support function at the Holly Springs site.

COS Implementation and Maturity:

Facilitate transformation workshops and enable teams to adopt COS methodologies such as Process Centric Teams (PCT), Visual Management, and Standard Work practices.
Lead the establishment of Tier Meetings, Visual Management boards, and Continuous Improvement (CI) routines to drive operational alignment with the site's Compelling Business Needs (CBNs).
Promote Leader Standard Work through Gemba walks, layered coaching, and process confirmation to sustain long-term COS integration.
Conduct COS Maturity Assessments to ensure continuous progress in COS adoption and improvement.

Continuous Improvement and Change Management:

Act as an OE Change Manager, Role Model, Coach, and Mentor to inspire and sustain the COS at all organizational levels.
Coordinate a portfolio of CI projects, ensuring alignment with COS objectives to sustain and enhance business performance.
Lead and/or coach complex CI projects and problem-solving workshops, using structured Lean Six Sigma approaches.

Training and Knowledge Sharing:

Support the development of COS and Lean Six Sigma training materials for both the site(s) and network.
Deliver CI training and coaching to drive certification, utilizing Lean Six Sigma methodologies.
Share Smart Practices across the Holly Springs CSL Seqirus site and the broader CSL global network.

Skills & Experience:

Bachelor's degree in Business Administration / Economics / Life Science / Data Science / Engineering, or a related field.
Minimum of 6 years of relevant Operational Excellence experience, with a proven track record in:
Leading OE transformational change programs (experience with production systems implementation preferred).
LEAN shop floor management and CI methodologies.
Lean Six Sigma (Green Belt certification preferred) with hands-on project experience.
Managing and reporting in a matrixed, highly regulated environment (Pharmaceutical industry and GxP experience preferred).
Strong leadership capabilities with a proven ability to coach and mentor cross-functional teams and leaders.
Excellent communication skills, capable of engaging with stakeholders at all organizational levels.
Advanced knowledge of data analytics tools (e.g., Minitab, JMP, MS PowerBI, MS Power Apps), and digital transformation initiatives.

About CSL Seqirus CSL Seqirus is part of CSL. As one of the largest influenza vaccine providers in the world, CSL Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. With state-of-the-art production facilities in the U.S., the U.K. and Australia, CSL Seqirus utilizes egg, cell and adjuvant technologies to offer a broad portfolio of differentiated influenza vaccines in more than 20 countries around the world. To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/.

Our Benefits For more information on CSL benefits visit How CSL Supports Your Well-being | CSL.

You Belong at CSL At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future. To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging

Equal Opportunity Employer CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement.

Watch our ‘On the Front Line’ video to learn more about CSL Seqirus

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More about this job

Skills

Process improvement
Leadership
Coaching
Microsoft Teams
Change management
Problem solving
Lean manufacturing
Lean Six Sigma Green Belt
Reporting
Pharmaceutical industry
Communication skills
Data analysis
Minitab
Microsoft Power BI
Power Apps

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