Jobs in the United States

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Network Infrastructure Engineer II
Akamai Technologies, Inc.
Boston, MA
- $83,200 to $149,800 USD / year
As a Network Infrastructure Engineer II, you will oversee operations in our global data centers. You will monitor and maintain our data centers, networks, and servers worldwide. You will…
Added just now
RA
Senior Program Manager & Key Client Lead, Data Centers
Ramboll Americas Engineering Solutions, Inc.
Boston, MA
- $150,000 to $225,000 USD / year
If this sounds like you, join Ramboll’s Power Systems team in North America as our Senior Program Manager & Key Client Lead, Data Centers, and help expand a strategic client relationship…
Added just now
Mainframe Technical Engineer
Highmark Health
Boston, MA
…z/OS, SMP/E, COUPLING FACILITY technical ecosystem including infrastructure, systems, networks, applications, integrations, etc. They will work closely with other technical professionals,…
Added just now
Power System Controls Engineer – Data Centers
Jacobs
Boston, MA
Jacobs’ Energy & Power business is seeking a Power System Controls Engineer to support conceptual planning, design, modeling, integration, and validation of Data Center controls ecosystem…
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Software Engineer, Infrastructure - Central Growth
Meta
Boston, MA
Software Engineer, Infrastructure - Central Growth Responsibilities:
Added 21 mins ago
ASIC Design Verification Engineer, Google TPU
Google
Sunnyvale, CA
Experience with industry-standard simulators, revision control systems and regression systems.
Added 21 mins ago
Staff Software Engineer, Cloud ML Compute Services
Google
Kirkland, WA
5 years of experience building and developing large-scale infrastructure, distributed systems or networks, or experience with compute technologies, storage, or hardware architecture.
Added 22 mins ago
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Lead Site Reliability Engineer
Jobgether
Remote, United States
- $150,000 to $175,000 USD / year
In this role, you will play a key leadership role in driving cloud infrastructure modernization, automation, and operational excellence. You will design, build, and maintain scalable…
Added 23 mins ago
Senior Test Engineer
Kelly Services
Phoenix, AZ
A growing communications technology organization is seeking a Senior Test Engineer to join its team in the Phoenix-area on a full-time basis. This onsite role focuses on testing and…
Added 27 mins ago
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(1119604) Lead Software Engineer - Emerging Technologies
Diversified Services Network, Inc.
Remote, United States
- $140,000 to $145,000 USD / year
Diversified Services Network, Inc. (DSN) is seeking a full-time Lead Software Engineer – Emerging Technologies to join our team in your choice of our Chicago, IL; Peoria, IL; Irving, TX; or…
Added 27 mins ago
DS
(1119604) Lead Software Engineer - Emerging Technologies
Diversified Services Network, Inc.
Remote, United States
- $140,000 to $145,000 USD / year
Diversified Services Network, Inc. (DSN) is seeking a full-time Lead Software Engineer – Emerging Technologies to join our team in your choice of our Chicago, IL; Peoria, IL; Irving, TX; or…
Added 27 mins ago
DS
(1119604) Lead Software Engineer - Emerging Technologies
Diversified Services Network, Inc.
Remote, United States
- $140,000 to $145,000 USD / year
Diversified Services Network, Inc. (DSN) is seeking a full-time Lead Software Engineer – Emerging Technologies to join our team in your choice of our Chicago, IL; Peoria, IL; Irving, TX; or…
Added 27 mins ago
DS
(1119604) Lead Software Engineer - Emerging Technologies
Diversified Services Network, Inc.
Remote, United States
- $140,000 to $145,000 USD / year
Diversified Services Network, Inc. (DSN) is seeking a full-time Lead Software Engineer – Emerging Technologies to join our team in your choice of our Chicago, IL; Peoria, IL; Irving, TX; or…
Added 28 mins ago
Applications Engineer
Continuum Resource Network
Foster City, CA
We are helping an on-demand, autonomous ride-hailing company find an Applications Engineer to support the configuration, maintenance, and ongoing improvement of Application Lifecycle…
Added 28 mins ago
Applications Engineer
Continuum Resource Network
Foster City, CA
We are helping an on-demand, autonomous ride-hailing company find an Applications Engineer to support the configuration, maintenance, and ongoing improvement of Application Lifecycle…
Added 28 mins ago
Application Administrator - Engineering Applications
Continuum Resource Network
Foster City, CA
We are helping an on-demand, autonomous ride-hailing company find an Applications Engineer to support the configuration, maintenance, and ongoing improvement of Application Lifecycle…
Added 34 mins ago
SS
Windows Systems Engineer
Samsung SDS America
Plano, TX
- $135,000 to $147,000 USD / year
We are seeking a Senior Microsoft Exchange and Active Directory Engineer to design, implement, maintain, and optimize enterprise messaging and directory services to ensure secure, highly…
Added 34 mins ago
SS
VMWare Engineer
Samsung SDS America
Plano, TX
- $156,000 to $166,000 USD / year
We are seeking a VMware Engineer to manage, maintain, and optimize enterprise virtualized environments, including VMware ESXi, vCenter, Horizon View, and end-user virtual desktop…
Added 34 mins ago
SS
Linux Engineer
Samsung SDS America
Plano, TX
- $156,000 to $166,000 USD / year
We are seeking a Linux Infrastructure Engineer to manage, optimize, and secure enterprise Linux environments across on-premises data centers and public cloud platforms. This role focuses on…
Added 37 mins ago
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Systems Architect - Manning - Information Systems Systems
El Rio Community Health Center
Tucson, AZ
- $47.06 to $77.6 USD / hour
The Systems Architect will work across all technical specialties including, but not limited to, applications, servers, storage, network, security, or other infrastructure.
Added 48 mins ago
AW
IT Infrastructure Engineer II
ANDREW WOMMACK MINISTRIES INC
Woodland Park, CO
- $6,500 to $7,501 USD / month
The IT Operations Engineer II supports the planning, engineering, deployment, and maintenance of secure, scalable, and reliable technology solutions across multiple departments and…
Added 52 mins ago
Senior / Staff Software Engineer
Axella
Boston, MA
We’re hiring a foundational technical leader to own engineering execution end-to-end - architecture, AI systems design, infrastructure, and the engineering standards and culture we build…
Added 53 mins ago
Full-Stack Mobile Software Engineer
Spirit AI
Alexandria, VA · Arlington, VA · Fairfax, VA · Tysons, VA · Washington, DC
We’re a lean, hands-on team where every engineer owns major pieces of the experience. You’ll work directly with founders and AI engineers to define how people emotionally connect with…
Added 54 mins ago
Associate AI Engineer
Core VC
Los Angeles, CA
You'll ship quickly and experiment aggressively. Complex systems are built on simple, reliable ones, and we've spent a lot of time building that foundation. Now we want to see how far we…
Added 54 mins ago
CV
AI Software Engineer
Cosmic Ventures
Remote, United States
- $30 to $50 USD / hour
At Cosmic Ventures, we don't just "consult." We build and deploy high-stakes agentic systems for Fortune 500 leaders across healthcare, finance, and e-commerce. We move at the speed of the…

Schrödinger

Senior Machine Learning Infrastructure Engineer

NY, United States

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Job details

Posting language: English
Posted: Nov 4, 2026

Original job description

We’re seeking a Senior Machine Learning Infrastructure Engineer to join us in our mission to transform the discovery of therapeutics and materials.

As a member of the Machine Learning team, you’ll play a key role in building and maintaining the systems that put ML models and AI agents to work in drug discovery. LiveDesign ML trains and serves models on live project data, both in our own clusters and in customers' LiveDesign environments. Bunsen is an agentic platform where every session runs an AI agent in its own isolated Kubernetes pod. We also run locked-down environments for federated-learning collaborations with pharma partners.

You'll own the infrastructure behind these products, across our own clusters and customer clouds on GCP and AWS. Today, ML engineers handle it alongside feature work. You'll make it your focus: repeatable customer deployments, strong isolation for AI-generated code, and reliable, cost-efficient GPU systems.

Who will love this job:

A Terraform or OpenTofu and Helm writer who has shipped with GitOps
A solid Python and shell scripter
A security-minded engineer who defaults to least privilege, managed secrets, and segmented networks
A clear communicator who enjoys working closely with ML engineers and scientists

What you’ll do:

Turn customer installs and upgrades into versioned, GitOps-driven releases (Helm, OpenTofu, Argo CD) with automated verification
Design isolation for multi-tenant agent sandboxes: network policy, workload identity, runtime sandboxing, and egress control
Secure CI/CD and the software supply chain with keyless auth, ephemeral runners, and pinned, signed images
Build and operate locked-down partner environments with private networking, default-deny egress, just-in-time access, and audit logging
Keep GPU-heavy training and inference reliable and cost-efficient, backed by observability, SLOs, and on-call

What you should have:

At least six years of infrastructure, platform, or SRE experience
In-depth understanding of Kubernetes operation (not just deployment)
Robust background with GCP (and some familiarity with AWS)

We’d prefer to hire someone who has experience with:

Running GPU workloads and model serving (vLLM, Knative) on Kubernetes
Sandboxing untrusted code (gVisor, Kata Containers, Cilium)
Shipping software into customer-owned or restricted-egress clouds
Argo Workflows or batch/HPC scheduling
Regulated environments (SOC 2, ISO 27001, GxP)
Operating LLM or agent platforms

Pay and perks:

Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, equity-based compensation, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have a company culture that is relaxed, but engaged, and over a month of paid vacation time. Our Office Management team also plans a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been included in Crain's New York Best Places to Work, BuiltIn's NYC Best Place to Work, and Newsweek's list of America's 100 Most Loved Workplaces.

Estimated base salary range: $110,000 - $160,000. Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team.

Sound exciting? Apply today and join us!

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.

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