Jobs in the United States

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Added 3 mins ago
MS
Part-Time Mission Analysis Engineer - Millennium Space Systems
Millennium Space Systems
El Segundo, CA
- $21.15 to $30.77 USD / hour
- Part-time
Added 3 mins ago
Software Developer, Phantom Works (Experienced or Senior)
The Boeing Company
Saint Charles, MO · Saint Louis, MO
The Boeing Company is seeking a Software Developer / Engineer (Experienced or Senior) to join the Phantom Works Weapons team in St. Charles, MO (St. Louis Area). This team supports future…
Added 7 mins ago
Senior Digital Design Verification Engineer
Renesas Electronics
Austin, TX
Renesas is seeking a Senior Digital Design Verification Engineer to join our team developing complex power management SoCs. These products integrate digital control, telemetry, fault…
Added 10 mins ago
Senior Commercialization Process Engineer
Natera
San Carlos, CA
Natera is seeking a Senior Commercialization Process Engineer to serve as the critical bridge between assay development and scalable lab production. This bench-level role is embedded early…
Added 11 mins ago
Senior Analyst, Compliance Technology
Coinbase
Montpelier, VT
We're hiring an Analytics Engineer to join the Compliance Technology team within the Platform organization. This team builds and operates data and detection capabilities that enable…
Added 11 mins ago
Quality Engineer, AI & Test Automation
Baylor Scott & White Health
Montpelier, VT
· The Quality Engineer, AI & Test Automation helps modernize BSWH’s quality approach by moving beyond traditional manual testing toward automation-first, engineering-integrated, and…
Added 11 mins ago
Senior Business Intelligence Engineer
Humana
Montpelier, VT
The Senior Business Intelligence (BI) Engineer engages with business value streams on diverse and complex opportunities leveraging a variety of technology platforms. The individual will…
Added 11 mins ago
Sr Site Reliability Engineer -Remote US
SitusAMC
Montpelier, VT
Strong scripting and automation skills (Python, Bash, and PowerShell).
Added 11 mins ago
Senior Financial Planning & Analysis Manager
Cornerstone OnDemand
Burlington, VT
We’re seeking a highly skilled and motivated Senior Financial Planning & Analysis (FP&A) Manager to serve as the finance partner to our Engineering and Product organizations. This critical…
Added 11 mins ago
Core Senior .NET Software Engineer
Evolent
Montpelier, VT
The Senior Software Engineer leads the design, development, and deployment of complex software solutions, ensuring scalability and maintainability. This role architects and implements…
Added 13 mins ago
Software Engineer, Triage Services
Apple
Cupertino, CA
Strong Python and system design skills, with a track record of owning architecture for services other teams depend on.
Added 19 mins ago
Senior System Development Engineer, Leo - Payload and Terminals
Amazon Kuiper Manufacturing Enterprises LLC
Redmond, WA
Experience with RF testing equipment automation using SCPI and a various RF equipment Python libraries like PyVisa.
Added 21 mins ago
Senior ASIC Silicon Validation Engineer (NetSec)
Palo Alto Networks, Inc.
CA
As a Silicon Validation Engineer on the ASIC team, you will ensure that the ASICs in our groundbreaking next-generation firewall products meet or exceed industry-leading requirements for…
Added 21 mins ago
Principal Site Reliability Engineer (AIOps)
Palo Alto Networks, Inc.
CA
Palo Alto Networks runs a large hybrid infrastructure and is one of the largest GCP customers. As a Sr Principal DevOps Engineer, you will be part of a team supporting the services running…
Added 21 mins ago
Scrum Master – Senior Software Engineer
RTX
United States
…within Raytheon is looking for a Software Scrum Master (SM) – Senior Software Engineer for the AN/TPY-2 radar program Orcas agile software team. The Orcas team provides subject matter…
Added 21 mins ago
Sr Service Engineer, Avionics Service and Support (Onsite)
RTX
United States
Collins Aerospace seeks an experienced Senior Systems Engineer to join its service engineering and support team in Cedar Rapids, Iowa, with the ability to provide on-site support as needed…
Added 21 mins ago
Senior Software Engineer - Modeling (Onsite)
RTX
United States
Develop and implement software solutions using programming languages such as C/C++, C#, Python, Java, and Lua.
Added 21 mins ago
Senior Software Engineer - AVI MIL FMS (Onsite)
RTX
United States
Collins Aerospace is currently seeking qualified candidates for Senior Software Engineer roles in our Military Avionics Flight Management department located in Cedar Rapids, Iowa. Teams are…
Added 23 mins ago
AVP, DevOps Engineer
LPL Financial Corp
Austin, TX
…effectiveness, and reliability outcomes while communicating progress to senior leadership and…
Added 24 mins ago
Senior Software Engineer - Agile Product Owner (Onsite)
RTX
United States
Senior Software Engineer - Agile Product Owner - Flight & Mission Simulation (Onsite)
Added 24 mins ago
Senior Manager Electro-Optical Integration and Test Section Lead
RTX
United States
…Responsibilities will be split between supporting EO program(s) as an engineer (~85%) and providing functional support to the section “EO Integration and Test Section”…
Added 24 mins ago
Senior Software Engineer
Advantest
San Jose, CA · Austin, TX
Advantest is seeking a Software Engineer to join the US AI and Automation Team. In this role, you will help design, develop, and deploy software solutions that integrate AI capabilities…
Added 25 mins ago
Senior Identity Security Engineer
Kansas City, MO
As a Senior Specialist, Enterprise Security, you will be at the forefront of the organization's identity security strategy, helping protect critical systems through advanced CyberArk…
Added 25 mins ago
Software Engineer Senior
GD Information Technology, Inc.
United States
As a Software Engineer Senior at GDIT, you will design, develop, integrate, and sustain secure software applications and data-driven solutions that support complex mission requirements.…
Added 26 mins ago
A
Principal Research Scientist I
AbbVie
North Chicago, IL
- $124,500 to $236,500 USD / year
…analytical scientists to frame high-value scientific questions, engineer and integrate complex analytical data, and develop fit-for-purpose models, visualizations, and digital solutions…

Schrödinger

Senior Machine Learning Infrastructure Engineer

NY, United States

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Job details

Posting language: English
Posted: Nov 4, 2026

Original job description

We’re seeking a Senior Machine Learning Infrastructure Engineer to join us in our mission to transform the discovery of therapeutics and materials.

As a member of the Machine Learning team, you’ll play a key role in building and maintaining the systems that put ML models and AI agents to work in drug discovery. LiveDesign ML trains and serves models on live project data, both in our own clusters and in customers' LiveDesign environments. Bunsen is an agentic platform where every session runs an AI agent in its own isolated Kubernetes pod. We also run locked-down environments for federated-learning collaborations with pharma partners.

You'll own the infrastructure behind these products, across our own clusters and customer clouds on GCP and AWS. Today, ML engineers handle it alongside feature work. You'll make it your focus: repeatable customer deployments, strong isolation for AI-generated code, and reliable, cost-efficient GPU systems.

Who will love this job:

A Terraform or OpenTofu and Helm writer who has shipped with GitOps
A solid Python and shell scripter
A security-minded engineer who defaults to least privilege, managed secrets, and segmented networks
A clear communicator who enjoys working closely with ML engineers and scientists

What you’ll do:

Turn customer installs and upgrades into versioned, GitOps-driven releases (Helm, OpenTofu, Argo CD) with automated verification
Design isolation for multi-tenant agent sandboxes: network policy, workload identity, runtime sandboxing, and egress control
Secure CI/CD and the software supply chain with keyless auth, ephemeral runners, and pinned, signed images
Build and operate locked-down partner environments with private networking, default-deny egress, just-in-time access, and audit logging
Keep GPU-heavy training and inference reliable and cost-efficient, backed by observability, SLOs, and on-call

What you should have:

At least six years of infrastructure, platform, or SRE experience
In-depth understanding of Kubernetes operation (not just deployment)
Robust background with GCP (and some familiarity with AWS)

We’d prefer to hire someone who has experience with:

Running GPU workloads and model serving (vLLM, Knative) on Kubernetes
Sandboxing untrusted code (gVisor, Kata Containers, Cilium)
Shipping software into customer-owned or restricted-egress clouds
Argo Workflows or batch/HPC scheduling
Regulated environments (SOC 2, ISO 27001, GxP)
Operating LLM or agent platforms

Pay and perks:

Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, equity-based compensation, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have a company culture that is relaxed, but engaged, and over a month of paid vacation time. Our Office Management team also plans a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been included in Crain's New York Best Places to Work, BuiltIn's NYC Best Place to Work, and Newsweek's list of America's 100 Most Loved Workplaces.

Estimated base salary range: $110,000 - $160,000. Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team.

Sound exciting? Apply today and join us!

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.

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