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Staff Software Engineer, Cortex AI Functions
Snowflake
Bellevue, WA
8+ years of relevant experience in software engineering, applied machine learning, or database systems, including independently leading multi-engineer projects from definition through…
Added 3 mins ago
Lead Software Engineer-Marketing Technology
AAPC
Remote, United States
AAPC seeks a hands-on lead software engineer to help build and evolve the customer-facing digital products, e-commerce experiences, and marketing technology that take people from discovery…
Added 4 mins ago
Tooling Design Engineer II
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United States
Experience with custom machine design: motors, actuators, linear rails/actuators, pneumatics, hydraulics, bearings, etc.
Added 5 mins ago
Compute Systems Architect - Expeditionary AI/HPC Data Centers
Anduril Industries
Mountain View, CA · Costa Mesa, CA
…process petabyte-scale data and convert it into decisions at machine speed from forward operating bases. These are not traditional data centers. They are air-transportable,…
Added 5 mins ago
Senior Data Engineer
Cricut
South Jordan, UT
We're hiring a Senior Data Engineer to shape the data foundation behind Cricut's product analytics, personalization, and AI initiatives. You'll own and evolve our event data platform, from…
Added 7 mins ago
Senior Software Engineer
FanDuel
Jersey City, NJ
As a Senior Software Engineer within FanDuel’s Risk and Trading Technology team, you will be an essential part of a cross functional agile team that directly impacts our business. You will…
Added 7 mins ago
Quantitative Software Engineer
FanDuel
Jersey City, NJ
As a Software Engineer within FanDuel’s Trading Solutions team, you will be an essential part of a cross functional agile team that directly impacts our business. You will work…
Added 10 mins ago
Lead Value Engineer - CGPR
Celonis
NY
We are looking for a Lead Value Engineer, Consumer Packaged Goods (CPG) - an industry expert who can bridge the gap between technical process mining, AI-driven automation, and strategic…
Added 12 mins ago
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Member of Technical Staff, VA
Abridge
San Francisco, CA · New York City, NY
- $210,800 to $248,000 USD / year
…delivery teams. You’ll work with other disciplines including design, product, machine learning, and infrastructure, and will have opportunities to learn from and contribute to projects…
Added 16 mins ago
Data Scientist III
Fetcherr
Atlanta, GA
Solid foundation in statistics, machine learning, and time-series forecasting, with sound judgment on model validation and experiment design.
Added 17 mins ago
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Controls Engineer
Actalent
Sturgis, MI
- $30 to $40 USD / hour
This Controls Engineer will focus on designing, programming, and commissioning control systems for custom automated machinery. Develop PLC software using ladder logic and structured text,…
Added 17 mins ago
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Manufacturing Engineer
Actalent
Three Rivers, MI
- $31.25 to $38.46 USD / hour
General understanding of assembly and machine processes
Added 17 mins ago
Manufacturing Engineer 3
Actalent
Pontiac, IL
Job Title: Manufacturing Engineer IIIJob DescriptionThis Manufacturing Engineer III role focuses on applying engineering theory and principles to optimize industrial layouts and…
Added 18 mins ago
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Process Engineer 2
DENSO Connection
Athens, TN
- $83,000 to $104,000 USD / year
May develop, design, test, and implement line modifications and arrangements, devices, fixtures, etc. to obtain continuous improvement of the production processes, achieve cost reduction,…
Added 18 mins ago
Machine Learning Engineer, Platform Architecture
Apple
Cupertino, CA
…unified system. You’ll collaborate with engineers across Apple to design how our technologies work in unison, drive development of our renowned system-on-a-chip architecture and develop…
Added 18 mins ago
Machine Learning Engineer, Platform Architecture
Apple
Cupertino, CA
…unified system. You’ll collaborate with engineers across Apple to design how our technologies work in unison, drive development of our renowned system-on-a-chip architecture and develop…
Added 19 mins ago
3rd shift Yarn Mechanic - (Commercial)
Tarkett USA Inc.
Dalton, GA
e) Assist the appropriate engineer in machine validation, both internally and at the customer’s facility while maintaining Tarkett work ethics and standards.
Added 20 mins ago
Software Engineer (Expert)
BAE Systems
Herndon, VA
IT system automation to include artificial intelligence and machine learning (AI/ML)
Added 21 mins ago
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Principal Software Engineering
AT&T Services, Inc.
Remote, United States
- $174,100 to $261,100 USD / year
Design and oversee enterprise-scale technology solutions that integrate business processes, data, applications, and AI capabilities.
Added 22 mins ago
Senior Engineer - Protection & Control
THE UNITED ILLUMINATING COMPANY
United States Of America, CT
…distribution substations control and automation system and design. Analyze and propose engineering solutions to improve substation networking, SCADA communication, local HMIs (Human Machine…
Added 27 mins ago
Sr. Mechanical Engineer, Satellites (Starlink)
SpaceX
Redmond, WA
As a mechanical design engineer within the satellite vehicle engineering organization you will get to solve complex structural, thermal, and electromechanical problems on the various space…
Added 34 mins ago
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Software Engineer, C++ (Onboard Platform)
Applied Intuition
Sunnyvale, CA
- $125,000 to $222,000 USD / year
- Design the runtime architecture of the onboard stack: how processes are scheduled, how they communicate, and how the system degrades when a component fails.
Added 34 mins ago
Software Engineer AI/ML Ops
BlackLine Systems, Inc.
United States
In new product design roles: develops and programs integrated software algorithms to structure, analyze and leverage data in product and systems applications in both structured and…
Added 35 mins ago
Software Engineer III - Java with Agentic AI
JPMC page
Chicago, IL · Plano, TX
As a Software Engineer III at JPMorganChase within the Consumer & Community Banking, you serve as a seasoned member of an agile team to design and deliver trusted market-leading technology…
Added 35 mins ago
Lead Software Engineer-Java with Agentic AI
JPMC page
Chicago, IL · Plano, TX
Strong software engineer with hands-on experience using AI coding assistants/agents to design, implement, test, and debug production code

Schrödinger

Senior Machine Learning Infrastructure Engineer

NY, United States

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Job details

Posting language: English
Posted: Nov 4, 2026

Original job description

We’re seeking a Senior Machine Learning Infrastructure Engineer to join us in our mission to transform the discovery of therapeutics and materials.

As a member of the Machine Learning team, you’ll play a key role in building and maintaining the systems that put ML models and AI agents to work in drug discovery. LiveDesign ML trains and serves models on live project data, both in our own clusters and in customers' LiveDesign environments. Bunsen is an agentic platform where every session runs an AI agent in its own isolated Kubernetes pod. We also run locked-down environments for federated-learning collaborations with pharma partners.

You'll own the infrastructure behind these products, across our own clusters and customer clouds on GCP and AWS. Today, ML engineers handle it alongside feature work. You'll make it your focus: repeatable customer deployments, strong isolation for AI-generated code, and reliable, cost-efficient GPU systems.

Who will love this job:

A Terraform or OpenTofu and Helm writer who has shipped with GitOps
A solid Python and shell scripter
A security-minded engineer who defaults to least privilege, managed secrets, and segmented networks
A clear communicator who enjoys working closely with ML engineers and scientists

What you’ll do:

Turn customer installs and upgrades into versioned, GitOps-driven releases (Helm, OpenTofu, Argo CD) with automated verification
Design isolation for multi-tenant agent sandboxes: network policy, workload identity, runtime sandboxing, and egress control
Secure CI/CD and the software supply chain with keyless auth, ephemeral runners, and pinned, signed images
Build and operate locked-down partner environments with private networking, default-deny egress, just-in-time access, and audit logging
Keep GPU-heavy training and inference reliable and cost-efficient, backed by observability, SLOs, and on-call

What you should have:

At least six years of infrastructure, platform, or SRE experience
In-depth understanding of Kubernetes operation (not just deployment)
Robust background with GCP (and some familiarity with AWS)

We’d prefer to hire someone who has experience with:

Running GPU workloads and model serving (vLLM, Knative) on Kubernetes
Sandboxing untrusted code (gVisor, Kata Containers, Cilium)
Shipping software into customer-owned or restricted-egress clouds
Argo Workflows or batch/HPC scheduling
Regulated environments (SOC 2, ISO 27001, GxP)
Operating LLM or agent platforms

Pay and perks:

Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, equity-based compensation, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have a company culture that is relaxed, but engaged, and over a month of paid vacation time. Our Office Management team also plans a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been included in Crain's New York Best Places to Work, BuiltIn's NYC Best Place to Work, and Newsweek's list of America's 100 Most Loved Workplaces.

Estimated base salary range: $110,000 - $160,000. Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team.

Sound exciting? Apply today and join us!

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.

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