Jobs in the United States

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Added 1 min ago
Senior Software Engineer - AI Agents
JeffreyM Consulting
San Francisco, CA
JeffreyM Consulting is partnering with an innovative, fast-growing AI technology startup to hire a Senior Software Engineer – AI Agents for its San Francisco-based engineering team.
Added 1 min ago
Professional Services Engineer - Federal
Hammerspace
Remote, United States
We are seeking a cleared Professional Services Engineer to deploy, configure, and optimize our AI Data Platform software within highly secure federal and defense environments. In this role,…
Added 3 mins ago
Lead Software Engineer
Kawneer
Alpharetta, GA · Norcross, GA
Arconic is currently in search of a Lead Software Engineer to join our Kawneer Business in Alpharetta, GA.
Added 3 mins ago
Engineering and Construction Manager
US AMR-Jones Lang LaSalle Americas, Inc.
Huntsville, AL · Reston, VA
Maintain accurate infrastructure and compliance documentation, including building drawings, single lines, and records required for regulatory compliance.
Added 3 mins ago
Reliability Engineer
US AMR-Jones Lang LaSalle Americas, Inc.
Remote, United States
…engineering support for operations and maintenance of buildings, infrastructure, and equipment assets. In coordination and full collaboration with the Engineering Services Reliability &…
Added 5 mins ago
AI
Senior Software Development Engineer
ADUS-Adobe Inc.
United States
- $159,200 to $301,600 USD / year
We're seeking a Senior Software Development Engineer to lead this exciting journey in our San Francisco location.
Added 10 mins ago
Staff, Mapping Software Engineer
Lucid Motors
Newark, CA
The GeoAI team is building the next generation of fleet-powered mapping infrastructure that
Added 15 mins ago
Software Engineer & Image Analyst
Amentum
Huntsville, AL
We are seeking an experienced and motivated Senior Image Analyst and Software Engineer to provide software engineering, database management, computer systems support, and engineering…
Added 15 mins ago
Sr. Systems Integration Engineer, Automated Drive
Rivian
Palo Alto, CA
Added 16 mins ago
Staff Engineer- DFT
MSI - (Marvell Semiconductor Inc.) US
Santa Clara, CA
Marvell’s semiconductor solutions are the essential building blocks of the data infrastructure that connects our world. Across enterprise, cloud and AI, and carrier architectures, our…
Added 17 mins ago
Senior Technical Product Marketing Manager, Performance
Fastly
Denver, CO · New York City, NY · San Francisco, CA · NY
Direct exposure to how AI agents, LLM crawlers, or automated fetchers interact with web and API infrastructure.
Added 17 mins ago
A
Network Infrastructure Engineer II
Akamai
Remote, United States
- $83,200 to $149,800 USD / year
As a Network Infrastructure Engineer II, you will oversee operations in our global data centers. You will monitor and maintain our data centers, networks, and servers worldwide. You will…
Added 18 mins ago
Lead Software Development Engineer in Test (SDET)
TCC Toyota Motor Credit Corporation Company
Plano, TX
We are seeking a Lead Software Development Engineer in Test (SDET) to join our team as an individual contributor. In this role, you will design, build, and maintain scalable test automation…
Added 18 mins ago
Install Base Manager, Startups
Vercel
Austin, TX · NY · San Francisco, CA
Confident leading conversations about AI, infrastructure, and technical products. You don't need to be an engineer, but you must be credible with technical buyers.
Added 18 mins ago
H
Inside Solution Engineer - Edge AI and Advanced Compute Practice
HP
Fort Collins, CO · Fort Collins
- $83,000 to $127,800 USD / year
The Inside Solution Engineer provides remote technical support to HP's field Solution Engineers, helping them validate solutions, resolve technical issues, and advance customer engagements.…
Added 18 mins ago
Staff Data Engineer
Abbott Laboratories
Madison, WI
The Staff Data Engineer is a senior, hands-on technical contributor within an Enterprise Data domain, owning technical design and the most complex implementation work for assigned data…
Added 19 mins ago
DMG Analyst (Multiple Levels)
Machinify
Remote, United States
…possible before. If you’ve spent years as a DBA or database engineer and want your work to have a direct, measurable impact on healthcare costs, we’d love to…
Added 19 mins ago
Infrastructure / SRE Engineer - USA
Inviso
Remote, United States
The Infrastructure / SRE Engineer is responsible for designing, building, and operating the cloud, infrastructure, deployment, observability, and reliability capabilities that allow…
Added 19 mins ago
Infrastructure / SRE Engineer - USA
Inviso
Remote, United States
The Infrastructure / SRE Engineer is responsible for designing, building, and operating the cloud, infrastructure, deployment, observability, and reliability capabilities that allow…
Added 24 mins ago
W
Senior CloudOps Engineer
Worldpac
Oakbrook, IL
- $150,000 to $170,000 USD / year
Position Overview Worldpac is seeking a highly experienced Senior CloudOps Engineer to design, build, operate, and continuously improve the cloud platforms that power our high-volume…
Added 25 mins ago
CO
Program Manager (Capital Improvement Program) - Environmental Services Department
City of San Jose
San Jose, CA
- $134,490.72 to $174,851.04 USD / year
…recycled water; sustainability initiatives; and the operation and infrastructure improvements of the San José-Santa Clara Regional Wastewater Facility. Together, ESD employees positively…
Added 26 mins ago
Pipeline Engineer
Actalent
Versailles, KY
We are seeking an experienced Pipeline Project Engineer to support the design and execution of natural gas, liquids, CO, hydrogen, and other midstream infrastructure projects. This position…
Added 26 mins ago
A
Utility Scale Structural/civil Engineer
Actalent
Kansas City, MO
- $110,000 to $150,000 USD / year
If you're an engineer who enjoys combining technical excellence with real-world project execution and wants to make an impact in the rapidly growing renewable energy industry, we encourage…
Added 28 mins ago
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Software Engineer
Mecka
New York, NY · San Francisco, CA
- $165,000 to $200,000 CAD / year
Mecka AI is building the data infrastructure layer for robotics and embodied AI.
Added 29 mins ago
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Staff Security Engineer – AI - R01573022
Brillio
Seattle, WA
- $120,000 to $130,000 USD / year
We are looking for an experienced AI Security Engineer who can drive AI and LLM security initiatives, establish security standards, and implement robust technical controls across AI/ML…

Schrödinger

Senior Machine Learning Infrastructure Engineer

NY, United States

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Job details

Posting language: English
Posted: Nov 4, 2026

Original job description

We’re seeking a Senior Machine Learning Infrastructure Engineer to join us in our mission to transform the discovery of therapeutics and materials.

As a member of the Machine Learning team, you’ll play a key role in building and maintaining the systems that put ML models and AI agents to work in drug discovery. LiveDesign ML trains and serves models on live project data, both in our own clusters and in customers' LiveDesign environments. Bunsen is an agentic platform where every session runs an AI agent in its own isolated Kubernetes pod. We also run locked-down environments for federated-learning collaborations with pharma partners.

You'll own the infrastructure behind these products, across our own clusters and customer clouds on GCP and AWS. Today, ML engineers handle it alongside feature work. You'll make it your focus: repeatable customer deployments, strong isolation for AI-generated code, and reliable, cost-efficient GPU systems.

Who will love this job:

A Terraform or OpenTofu and Helm writer who has shipped with GitOps
A solid Python and shell scripter
A security-minded engineer who defaults to least privilege, managed secrets, and segmented networks
A clear communicator who enjoys working closely with ML engineers and scientists

What you’ll do:

Turn customer installs and upgrades into versioned, GitOps-driven releases (Helm, OpenTofu, Argo CD) with automated verification
Design isolation for multi-tenant agent sandboxes: network policy, workload identity, runtime sandboxing, and egress control
Secure CI/CD and the software supply chain with keyless auth, ephemeral runners, and pinned, signed images
Build and operate locked-down partner environments with private networking, default-deny egress, just-in-time access, and audit logging
Keep GPU-heavy training and inference reliable and cost-efficient, backed by observability, SLOs, and on-call

What you should have:

At least six years of infrastructure, platform, or SRE experience
In-depth understanding of Kubernetes operation (not just deployment)
Robust background with GCP (and some familiarity with AWS)

We’d prefer to hire someone who has experience with:

Running GPU workloads and model serving (vLLM, Knative) on Kubernetes
Sandboxing untrusted code (gVisor, Kata Containers, Cilium)
Shipping software into customer-owned or restricted-egress clouds
Argo Workflows or batch/HPC scheduling
Regulated environments (SOC 2, ISO 27001, GxP)
Operating LLM or agent platforms

Pay and perks:

Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, equity-based compensation, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have a company culture that is relaxed, but engaged, and over a month of paid vacation time. Our Office Management team also plans a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been included in Crain's New York Best Places to Work, BuiltIn's NYC Best Place to Work, and Newsweek's list of America's 100 Most Loved Workplaces.

Estimated base salary range: $110,000 - $160,000. Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team.

Sound exciting? Apply today and join us!

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.

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