Jobs in the United States

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Added 1 day ago
Associate Scientist, Purification
Satomic
San Diego, CA
Reports To: Senior Principal Scientist - Purification
Added 1 day ago
Medical Laboratory Scientist II
University of Maryland Medical System
Chestertown, MD
Independently identifies and resolves analytical problems, troubleshoots equipment issues and takes corrective action in evaluating testing procedures, patient results and specimen…
Added 1 day ago
Associate Principal Scientist – Regulatory CMC, Medical Device and Combination Product (MDCP)
Organon LLC
NJ · PA
Reporting to the Director or Executive Director in Organon Regulatory Chemistry, Manufacturing and Controls (CMC), the Associate Principal Scientist is responsible for developing and…
Added 2 days ago
Associate Principal Scientist, Upstream Process Development
Merck Sharp & Dohme LLC
NJ
We are seeking a highly motivated and energetic individual to join our team as an Associate Principal Scientist. In this role, a successful candidate will work closely with a highly…
Added 2 days ago
Data Scientist (Remote)
Koniag Government Services
Nashville, TN
The Data Scientist will be responsible for the design, development, implementation, and ongoing refinement of advanced data science and machine learning solutions that support Call Center…
Added 3 days ago
VH
Supervisory Research Health Scientist
Veterans Health Administration
San Antonio, TX
- $127,624 to $165,917 USD / year
The Supervisory Research Health Scientist serves as Associate Director for Research (AD/R), Geriatric Research, Education, and Clinical Center (GRECC), South Texas Veterans Health Care…
Added 3 days ago
Senior/Principal Scientist, Analytical Development
Workforce Genetics
Beltsville, MD
Our client is seeking a Sr. Scientist to lead development, qualification, and validation of analytical methods supporting characterization, release, and stability testing of biologics and…
Added 3 days ago
Associate Principal Scientist, Regulatory Chemistry Manufacturing & Controls (CMC) Product Lead
Organon & Co.
Florham Park, NJ
Reporting to the Director or Executive Director in Organon Regulatory Chemistry, Manufacturing and Controls (CMC), the Associate Principal Scientist is responsible for developing and…
Added 4 days ago
Associate Sr. Scientist- LCMS
Resolian
Malvern, PA
The Associate Senior Scientist performs advanced scientific activities supporting study delivery, method development and validation, data analysis, troubleshooting, and client-focused…
Added 5 days ago
Associate Principal Scientist, Mixed Modality Product Development
Merck Sharp & Dohme LLC
NJ
We are seeking a highly motivated candidate for the position of Associate Principal Scientist (R4) focused on developing parenteral drug products across a range of modalities (small…
Added 8 days ago
A
Principal Data Scientist
AbbVie
Irvine, CA
- $124,500 to $236,500 USD / year
The Principal Data Scientist is the senior technical and scientific leader for AbbVie's omnichannel engagement analytics, a data and analytics-driven engagement optimization program…
Added 8 days ago
A
Principal Data Scientist
AbbVie
Mettawa, IL
- $124,500 to $236,500 USD / year
The Principal Data Scientist is the senior technical and scientific leader for AbbVie's omnichannel engagement analytics, a data and analytics-driven engagement optimization program…
Added 9 days ago
Senior Associate Scientist, Purification, RNA Process Development
Bristol Myers Squibb
Cambridge, MA
The Senior Associate Scientist executes robust experiments for drug substance programs spanning early- to late-stage development across circular and linear mRNA modalities. Reporting to the…
Added 9 days ago
Data Scientist 2
RealmOne
Central Maryland, MD
We are seeking a Data Scientist to leverage data in MDRs focused on data integrity, value assessment, and assessing data size and types. You will work with analytics and connect the dots…
Added 9 days ago
Associate Principal Scientist, Upstream Process Development
Merck
Rahway, NJ
We are seeking a highly motivated and energetic individual to join our team as an Associate Principal Scientist. In this role, a successful candidate will work closely with a highly…
Added 9 days ago
Principal Scientist, Drug Safety
Merck
North Wales, PA
Reporting to a CSRM Scientific Associate Vice President, CSRM Associate Vice President, or CSRM Distinguished Scientist, this role leads the development and maintenance of risk management…
Added 9 days ago
Principal Data Scientist
Arena Technical Resources, LLC
Oklahoma City, OK
The Principal Data Scientist serves as the technical authority and
Added 10 days ago
Senior Associate Scientist, Purification, RNA Process Development
E.R. Squibb & Sons,L.L.C.
Cambridge, MA
The Senior Associate Scientist executes robust experiments for drug substance programs spanning early- to late-stage development across circular and linear mRNA modalities. Reporting to the…
Added 10 days ago
Senior/Staff/Principal Data Scientist (HHS)
Skylight
United States
…product teams make informed decisions. They apply a variety of analytical models to find meaningful insights in both structured and unstructured data, and they communicate these insights in…
Added 10 days ago
Associate Principal Scientist, Biopharmaceutics
Merck Sharp & Dohme LLC
NJ
We are seeking an experienced Associate Principal Scientist to join our team and lead biopharmaceutics strategy for subcutaneously (SC) administered biologics across the pipeline - from…
Added 10 days ago
Associate Principal Scientist, Analytical R&D (GxP Supervisor 2nd Shift)
Merck Sharp & Dohme LLC
NJ
The Associate Principal Scientist will serve as the scientific and operational supervisor for a team of specialists and scientists in Rahway supporting various GMP analytical activities…
Added 11 days ago
Associate Principal Scientist, Regulatory Chemistry Manufacturing & Controls (CMC) Product Lead
Organon LLC
NJ · PA
Reporting to the Director or Executive Director in Organon Regulatory Chemistry, Manufacturing and Controls (CMC), the Associate Principal Scientist is responsible for developing and…
Added 14 days ago
Domain Principal Architect (Remote)
CareFirst
Washington, DC
…strategies, standards, and guidelines. Identify and support development of reusable domain…
Added 15 days ago
Senior/Staff Data Scientist (ACF)
Skylight
United States
…product teams make informed decisions. They apply a variety of analytical models to find meaningful insights in both structured and unstructured data, and they communicate these insights in…
Added 15 days ago
Associate Principal Scientist, Upstream Process Development
Merck Sharp & Dohme LLC
NJ
We are seeking a highly motivated and energetic individual to join our team as an Associate Principal Scientist. In this role, a successful candidate will work closely with a highly…

Satomic

Associate Scientist, Purification

San Diego, CA, United States

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Job details

Experience: M.S. in Analytical Chemistry, Chemistry or a related field with 0-2+ years of relevant industry experience; or B.S. with 4+ years of relevant industry experience.
Posting language: English
Posted: Nov 6, 2026

Original job description

Associate Scientist - Purification Department: Chemistry Location: San Diego, CA Type: Full Time Reports To: Senior Principal Scientist - Purification

About Satomic Satomic’s mission is to close the gap from idea to molecule with faster navigation of chemical space. We are building an automated chemistry platform that integrates laboratory robotics, software and AI to transform small-molecule synthesis and drug discovery. Purification is central to that mission. By isolating and delivering pure compounds quickly and reliably, this role makes more of chemical space reachable, so our partners can focus on the hardest challenges in drug discovery and human health.

Role Overview We are seeking a hands-on analytical chemist to run Satomic's chromatography-based purification fleet day to day. Our instrument stack includes SFC and reverse-phase LC instrumentation, with mass spectrometry driven detection and fraction collection. Purification is a vital function of Satomic’s platform, and our throughput targets depend on a fleet that runs reliably and consistently as one integrated system Working with the Purification team, you will execute high-throughput, mass-directed purifications, help standardize methods and workflows, and keep instruments running through preventive maintenance and fast troubleshooting. You will keep the sample queue moving, be the first line of defense for routine troubleshooting, and handle post-purification sample management, such as fraction analysis, evaporation, consolidation, and reporting. This is a lab-based role for someone who thrives in a fast paced, high-throughput environment and cares about data quality and sample integrity. Experience with reversed-phase LC purification is expected; experience with SFC purification is a plus.

Expected Outcomes

By 30 days, you will have:

Completed onboarding, safety training and lab operations orientation.
Become proficient at the current SFC and reverse-phase LC systems, and run 10 analytical screens and preparative purifications using standard methods with guidance.
Started running daily system suitability checks and following sample tracking and documentation procedures.

By 90 days, you will have:

Independently run routine purifications on the preparative fleet, contributing to a sustained throughput of 50 samples per instrument per day, independently, including mass-directed fraction collection and data review.
Handled routine maintenance and first-line troubleshooting, including when to escalate.
Taken on post-purification steps: fraction analysis, evaporation, consolidation and reporting.
Written or updated at least one SOP for instrument operation, fraction collection or maintenance.

By 1 year, you will have:

Become a reliable operator who consistently meets the throughput and turnaround targets set by the Purification team.
Resolved most common instrument issues without escalation, reducing unplanned downtime.
Helped refine standard methods and post-purification steps based on what you’ve seen in daily runs.
Supported software and automation teams in testing and rolling out purification workflows.

By 5 years, you will have:

Built deep expertise in high-throughput, mass-directed SFC and LC purification.
Taken on method development and workflow improvements with growing independence.
Trained new team members on instruments, methods and SOPs.

What you will own This is a new team with new instrumentation, so you will help establish how the purification instrumentation runs day to day.

Daily execution of preparative SFC and reverse-phase LC purifications from the standing sample queue, including run setup, mass-directed fraction collection and data review.
Analytical SFC and LC/MS screening of crude samples to select conditions from Satomic's standardized method set.
Preventive maintenance, daily system suitability checks and first-line troubleshooting across SFC/MS, LC and LC/MS systems; coordinating vendor service visits with Laboratory Operations team
Post-purification handling: fraction consolidation, evaporation, QC analysis of outgoing products and accurate sample tracking.
Solvent, waste, column and consumable management for the purification fleet with Laboratory Operations team
Writing and maintaining SOPs for instrument operation, fraction collection and routine maintenance.
Accurate documentation, sample tracking, and data analysis to keep data quality and sample integrity high
Raising workflow issues and proposing improvements to Purification team
Partner with chemists and technicians to understand incoming samples and meet purity and quantity targets; support software and automation teams during workflow testing and rollout.

Qualifications

M.S. in Analytical Chemistry, Chemistry or a related field with 0-2+ years of relevant industry experience; or B.S. with 4+ years of relevant industry experience.
Hands-on experience purifying organic small molecules by preparative chromatography, with SFC experience strongly preferred and preparative LC experience expected; experience with mass-directed purification and fraction collection.
Proficiency with analytical LC/MS and/or SFC/MS for screening and purity assessment.
Experience operating, maintaining and troubleshooting LC, LC/MS or SFC/MS instruments; experience in a high-throughput purification or compound-library environment is a plus.
Familiarity with Waters analytical and preparative SFC instruments and software, and with Agilent LC/MS systems, is a plus.
Exposure to purification informatics, lab automation or liquid handlers is a plus.
Strong record keeping, and the ability to work independently and collaboratively in a fast-paced, cross-functional team.

Overview of Satomic’s Interview Process

Hiring Manager Call (15 minutes): The hiring manager will contact you to schedule a 15 minute call to give an overview of Satomic and the role and better understand your career goals, experience, and motivations.
Cores Interviews (3x45 min): The hiring manager will coordinate a block for you to have four 45 minute back-to-back interviews with different members of the Satomic team, who will ask questions about your past experience and fit for the role.
Final round (60 minutes): Candidates that are selected for the final round will be asked to present on their past work most relevant to the open position (30 minutes) and discuss a representative scenario ("case study") live with the interview panel (30 minutes). The scenario will be given to the candidate at least one week prior to the final interview.

Compensation

This role offers a base salary of $80,000-$115,000, along with meaningful equity ownership and competitive benefits. We are an early-stage company and design offers to balance cash compensation and equity ownership. The salary range above reflects base pay only, and we work with candidates to build a package that aligns with their preferences. Final offers are based on a candidate's experience and expected impact. For candidates exceptionally aligned with the role we are comfortable positioning offers toward the top of this range and beyond.

Diversity & Inclusion We know there’s a serious lack of diversity in our industry, and that needs to change. At Satomic, we’re committed to helping drive that change. Our culture is built on inclusion, humility, humanity, and ingenuity: values that guide how we work with one another and how we approach the challenges of scaling science. We believe that bringing together people with diverse perspectives, experiences, and ways of thinking is not just the right thing to do, but makes us stronger: we want every member of our team to feel they belong and can do the best work of their career here. Our mission is to close the gap from idea to molecule. That mission carries responsibility: the chemistry we enable can accelerate access to life-changing medicines and technologies, but it can also pose risks if used carelessly. We’re not agnostic to how our platform is applied. We care deeply about ensuring it is used for good. Building a team of diverse and thoughtful voices gives us the best chance of delivering a platform that not only advances the future of chemistry and drug discovery, but does so responsibly and with lasting positive impact on our world.

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More about this job

Skills

Mass spectrometry
Preventive maintenance
Troubleshooting
Reporting
Onboarding
Documentation
Workflow
Data analysis
Analytical chemistry
Record keeping
Work independently
Use questioning techniques

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