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Sanofi Group

Sr. Equipment Process Engineer- Upstream

Framingham, MA, United States

$100,500.00 - $145,166.66

Apply on usnlx.com About employer

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Job details

Pay: $100,500.00 - $145,166.66
Experience: Candidates without a bachelor's degree must have at least 8 years of such experience.
Posting language: English
Posted: Nov 10, 2026

Original job description

Framingham, MA

Full time

R2877462

Job title : Sr. Equipment Process Engineer- Upstream

Location: Framingham, MA

About Job

The Sr. Equipment Process Engineer- Upstream is the technical owner for an assigned portfolio of manufacturing, utility, facility, or laboratory equipment. This role improves equipment safety, compliance, availability, and lifecycle performance by combining hands-on troubleshooting with effective maintenance strategies, equipment changes, technical documentation, and cross-functional leadership.

Join a global network that powers how Sanofi delivers - seamlessly, purposefully, and at scale. In Manufacturing & Supply, you'll help reimagine how life-changing treatments reach people everywhere, faster.

About Sanofi

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main Responsibilities

Own equipment performance and lifecycle: Maintain asset health, design basis, operating limits, criticality, failure history, documentation, maintenance strategy, obsolescence risks, and improvement priorities.
Lead troubleshooting and field support: Diagnose complex mechanical, electrical, instrumentation, and control-interface issues. Partner directly with mechanics and technicians through repair, testing, and return to service.
Build executable maintenance plans: Develop and technically approve complete work packages, including scope, sequence, labor, parts, tools, permits, LOTO, acceptance criteria, post-maintenance testing, and restoration requirements.
Optimize preventive maintenance and spares: Create risk-based PM strategies, equipment BOMs, critical-spares lists, stocking recommendations, and obsolescence mitigation plans using equipment criticality, failure modes, OEM guidance, and operating history.
Lead equipment changes and projects: Define technical requirements and lead design reviews, vendor selection, FAT/SAT, commissioning, qualification, turnover, training, maintenance readiness, and documentation for modifications and new equipment.
Own technical quality actions: Lead equipment-specific change controls and CAPAs, provide timely deviation assessments, and ensure approved hardware changes are implemented, tested, documented, and effectively closed.
Drive reliability improvement: Use downtime, repeat work, deviations, maintenance findings, and condition data to eliminate bad actors and improve reliability, maintainability, safety, and compliance.
Coordinate vendors and stakeholders: Develop technical scopes, assess vendor capability and performance, and collaborate with Operations, Quality, Validation, Metrology, HSE, Automation, Engineering, Procurement, Stores, and Finance.

Key Deliverables

Technically complete, schedule-ready work packages and maintenance master data.
Risk-based PM programs, accurate equipment BOMs, and critical-spares strategies.
Timely, technically sound closure of deviations, CAPAs, change controls, and engineering actions.
Reduced repeat failures, emergency work, avoidable downtime, and obsolete-component exposure.
Complete maintenance readiness and technical turnover for equipment changes and new assets.
Accurate, traceable, and inspection-ready drawings, specifications, manuals, and records.

About You

Basic Qualifications

Bachelor's degree in mechanical, electrical, chemical, biomedical, or related engineering discipline, with at least 3 years of relevant engineering experience in manufacturing, facilities, utilities, laboratories, or complex process equipment in a regulated or high-reliability environment.
Candidates without a bachelor's degree must have at least 8 years of such experience.
Demonstrated equipment troubleshooting capability using drawings, manuals, data, failure history, and structured root-cause methods.
Experience developing job plans, PM tasks, technical specifications, spare-parts recommendations, or maintenance strategies.
Experience supporting equipment modifications, commissioning, qualification, change control, deviations, or CAPAs.
Ability to work effectively in the field and communicate technical risk and recommendations to technical teams and leaders.

Preferred Qualifications

Experience in biopharmaceutical, pharmaceutical, medical-device, SUT, or other cGMP manufacturing.
Working knowledge of CMMS/EAM systems, equipment BOMs, work-order controls, and maintenance master data.
Knowledge of reliability methods, including criticality, FMEA, root cause analysis, condition monitoring, bad-actor elimination, and lifecycle planning.
Experience with P&IDs, electrical and mechanical drawings, instrumentation, controls interfaces, and OEM technical packages.
PE, CMRP/CRL, Lean/Six Sigma, project-management training, or related professional certification.

Why Choose US?

Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs.
Shape the future of medicine and vaccine delivery with cutting-edge technology, ensuring seamless launches and a resilient global supply.
Power industry-leading performance by leveraging digital, data, and AI-driven innovation – at speed and scale.
Transform lives worldwide by delivering life-changing treatments anywhere, anytime.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SG

#vhd

Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

Sanofi US endeavours to make our career center accessible to any and all users. If you are experiencing difficulty and need assistance applying online, please call 1-866-SANOFI2 (1-866-726-6342) or click here (https://cscontactus.sanofi.us/accessibilityQuestionComments.aspx)

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$100,500.00 - $145,166.66

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

We are an R&D driven, AI-powered biopharma company committed to improving people’s lives and creating compelling growth. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives.

We want to build a healthier, more resilient world, and turn the impossible into the possible by discovering, developing, and delivering medicines and vaccines for millions of people around the world.

Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo)

Start a career that makes a difference.

Reinvention is in our DNA. It’s what drove our evolution from a small French enterprise to one of the world’s leading biopharma companies. Whether it’s using AI to shorten drug-discovery times or building trust in healthcare, you could be helping our teams make life better for patients, partners, and communities.

This is where you grow your career. We open the door for you to explore new opportunities, push your limits, and connect with people who are driven by a shared purpose: we chase the miracles of science to improve people’s lives.

Apply on usnlx.com About employer

More about this job

Skills

Troubleshooting
CMMS
Root cause analysis
Technical drawings
Lean manufacturing
Project management

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Work requirements

Jobs in the United States