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Configuration Analyst III
Blue Origin Personnel, LLC
Space Coast, FL
…accurate. Applies company CM standards and contributes to tool and process improvements. Works with project engineers, design engineering, construction, test and launch operations to…
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Manufacturing Engineer II, III, Sr. - Combustion Devices
Blue Origin Personnel, LLC
Huntsville, AL
· Experience in a manufacturing engineering role: 5+ years for Level 3 Manufacturing Engineer, 8+ years for Sr Manufacturing Engineer)
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…senior leadership teams to help identify, develop, and implement process…
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Blue Origin Personnel, LLC
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This role applies engineering techniques to design, install, modify, analyze, repair and test fluid systems. Development, release, and support of engineering artifacts across the…
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Fluid and Propulsion Design Engineer III – Human Rated Crewed Lunar Lander
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Denver, CO
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B.S. degree in Aerospace Engineering or Physics with 12+ years of experience or M.S. with 10+ years of experience
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United States
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Sr. Transportation Project Manager
Consor Engineers
Wesley Chapel, FL · Pace, FL · Jacksonville, FL · West Palm Beach, FL · Miami, FL · Ft. Lauderdale, FL · Plantation, FL · Tampa, FL
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Engineer I-Quality
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C
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Regeneron Pharmaceuticals, Inc (USA)

Process Development Engineer II, Upstream Development - Gene Therapy

United States

Salary Range (annually) $95,800.00 - $156,400.00

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Job details

Pay: Salary Range (annually) $95,800.00 - $156,400.00
Posting language: English
Posted: Nov 9, 2026

Original job description

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Process Development Engineer II to join our Preclinical Manufacturing and Process Development (PMPD) group, responsible for upstream development efforts to support manufacturing process development functions. In this role, you will work as part of a multi-functional team to provide Adeno-Associated Virus (AAV) manufacturing processes and products with the aim of providing treatment to unmet medical needs through gene therapy. This is a growth opportunity that combines the excitement and opportunity of a start-up with the security and institutional knowledge gained from working for a larger firm. You will have the unique opportunity to work on production processes across a wide range of scales from 200 mL to 500 L, and support programs across the development lifecycle, from research through clinical development, regulatory filing, and approval.

When & where:

Shift Requirements: Full-time
Location: On-site in Tarrytown, NY
Other requirements: Job will periodically require short duration physical exertions, including light-medium weight lifting

Discover your role:

Design optimized, well-characterized, and robust seed train and bioreactor processes for upstream viral vector production in suspension cell lines, suitable for future GMP clinical and commercial production
Lead the design and execution of studies to optimize transfection, bioreactor, and scale-up parameters for viral production using multivariate design of experiment approaches
Serve as an upstream subject matter expert and lead technology transfer to clinical manufacturing for future gene therapy programs
Conduct technology development studies aimed at enhancing process understanding and improving viral vector production, including novel reagent screening and equipment evaluation, plasmid system improvements, stable producer cell line process development, and perfusion process development
Support the development of a next generation suspension lentiviral vector production process in collaboration with Regeneron Cell Medicine colleagues
Lead and support ongoing data management initiatives within the team

This role requires:

Bachelor’s degree with 6-8+ years of relevant experience, or Master’s degree with 4-6+ years of relevant experience, in Chemical Engineering, Biochemical Engineering, Biochemistry, or a related field
Solid experience with HEK mammalian cell culture and AAV-based gene therapy vector production
A history of developing upstream steps within bioprocesses; experience with bioreactor scale-up and manufacturing technology transfer is preferred
JMP experience preferred; lentiviral vector production experience is a plus
Proven experience with some of the following systems is preferred: BioProfile FLEX2, AMBR250 bioreactors, bench top bioreactors, single-use pilot scale bioreactors (50-500 L), wave rockers, biosafety cabinets, incubators, autoclave, Pi Historian, JMP, Benchling
High self-motivation and proactiveness, with strong initiative and drive to set challenging goals
Strong experimental, analytical, and communication skills, with the ability to design experiments, statistically interpret results, accurately document development data, and clearly present findings to diverse audiences
Coachability, self-awareness, and a growth mindset, with a willingness to learn from experience, embrace constructive feedback, and develop new skills
Adaptability to a dynamic pipeline and priorities, with the ability to manage multiple tasks, work effectively with incomplete information, and contribute both independently and collaboratively

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually) $95,800.00 - $156,400.00

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More about this job

Skills

Manufacturing processes
Production processes
ML
Research
Good manufacturing practices
Collaboration
Data management
Chemical engineering
Communication skills
Adaptability
Compensation and benefits
Recruitment

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