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Pfizer, Inc.

Clinical Development Scientist, Senior Manager

PA, United States
CA, United States
IL, United States
MA, United States
CT, United States
NY, United States

$139,100 to $231,900 USD / year

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Job details

Pay: $139,100 to $231,900 USD / year
Apply by: Nov 20, 2026
Posting language: English
Posted: Nov 9, 2026

Original job description

The Clinical Development Scientist (Senior Manager) is responsible for scientific oversight, data integrity, and quality of clinical trials in Internal Medicine, with direct responsibility for clinical deliverables for one or more studies. They may also supervise and mentor others.

JOB RESPONSIBILITIES

Provides clinical support for one or more studies; may be accountable for program level clinical deliverables
May provide input to the protocol design document; contributes to development of the protocol, including protocol amendments, Protocol Administrative Change Letters, and Dear Investigator Letters
Supports the study team in internal protocol review governance submissions and interactions; supports the Global Development Lead in study and disease area strategy; may participate in protocol-related KOL and Health Authority interactions
May develop Study Informed Consent Documents and responses to external stakeholder (e.g., Health Authority and Independent Ethics Committee) requests
Provides clinical input to the development of the Statistical Analysis Plan and Tables, Listings, and Figures
Provides clinical input to the development of the clinical data collection strategy, instruments, and data review plan, ensuring alignment with the protocol and SAP, optimized data collection principles, and clinical data review best practice; performs clinical data review; may present data to internal and external stakeholders; partners with site-facing colleagues in support of data issue resolution; ensures all clinical queries are appropriately addressed in support of database lock
Provides clinical input to the development of the Safety Review Plan and Safety Narrative Plan; reviews safety data and may update clinical documents in response to emerging safety profile; tracks and reconciles Serious Adverse Events; participates in clinical safety data discussion during Safety Review Team meetings in collaboration with Medically Qualified Individual(s); reviews safety narratives
Provides clinical input to the development of the Risk Management Plan; conducts clinical activities consistent with the approved Plan and partners with key stakeholders to develop and implement risk mitigations
Supports establishment and management of External Data Monitoring Committees and Adjudication Committees, including chartering, contracting, provision and presentation of data, and documentation and dissemination of Committee recommendations
Contributes to site selection criteria, provides clinical input to selection of sites, and may deliver protocol training to site-facing colleagues
Participates in investigator meeting planning and may develop and deliver protocol training; may develop and deliver ongoing protocol training in response to e.g., protocol amendments, emerging data issues, and quality events
May serve as a clinical point of contact with investigators and study team for questions relating to clinical aspects of the protocol; contributes to clinical response development, delivery, documentation, and curation (e.g., in FAQ)
May author protocol deviation sub-categories; ensures protocol deviations identified during clinical data review are reported; ensures all reported protocol deviations are appropriately managed and reconciled; may lead protocol deviation trends review
Ensures TMF compliance for clinical documents
Provides clinical input and review of the Clinical Study Report
Provides clinical support to disclosure of safety and efficacy data and trial conclusions; may contribute to publications
Provides clinical support to audits and inspections, including responding to and addressing audit and inspection findings
May contribute to clinical sections of regulatory filings (e.g., Briefing Documents, Pediatric Investigational Plan, Investigator Brochure, IND/NDA Annual Reports, Periodic Safety Update Reports, responses to Health Authority requests)
Contributes to continuous improvement / process enhancement activities and innovative approaches to maximize effectiveness of clinical trial execution
May supervise, mentor, or develop others

BASIC QUALIFICATIONS

Science degree (PhD, PharmD, or equivalent) with at least 1 year, or MA/MS with at least 5 years, or BA/BS with at least 6 years of Clinical Research experience in a similar role in the biopharmaceutical industry

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Relocation support available

PREFERRED QUALIFICATIONS

Cardiometabolic disease experience, e.g., obesity, diabetes, endocrinology, etc.
Clinical research experience in the biopharmaceutical industry in study design, start-up, conduct,and close-out, including regulatory submissions and inspections
Scientific productivity via publications, posters, abstracts and/or presentations
Knowledge of clinical development, global and regional regulation, and ICH/GCP
Clinical and administrative capabilities; effective verbal and written communication skills
Track record of achievement in pharmaceutical development; able to execute clinical development during design, start-up, conduct, close-out, and reporting
Understands the complexities and recent developments in the principal disease areas; competent discussing scientific and regulatory aspects of drug development
Able to set priorities to deliver milestones according to budgets and priorities
Effective leader; able to mentor/coach, delegate to, and oversee others; able to develop others’ skills and move them toward autonomy
Able to resolve conflicts equitably; fosters open dialogue; addresses conflicts; reads situations quickly; negotiates agreements; escalates issues when appropriate; takes responsibility for decisions
Shares wins and success; defines success in terms of the whole team; develops strong team morale and spirit; creates a sense of belonging
Takes personal responsibility for delivery of results
Able to demonstrate perspective and poise in uncertainty and organizational change
Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity.
Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Global travel may be required

Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.

The annual base salary for this position ranges from $139,100.00 to $231,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

Medical

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More about this job

Skills

Clinical trials
General medicine
Statistics
SAP
Manage quantitative data
Risk management
Documentation
Regulatory compliance
Inspection
Process improvement
BASIC
Clinical research
Leadership
Presentation skills
Google Cloud
Communication skills
Reporting

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