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Added 14 mins ago
A&
Salesforce Developer/Architect
Astor & Sanders
Remote, United States
- $150,000 to $190,000 USD / year
…provider headquartered in McLean, VA and is seeking a Salesforce Developer/Architect to join their team. This is a full-time position and hybrid onsite in the DMV…
Added 14 mins ago
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ServiceNow Developer
Astor & Sanders
San Diego, CA
- $170,000 to $190,000 USD / year
…provider headquartered in McLean, VA and is seeking a ServiceNow Developer. This is a full-time onsite position in San Diego,…
Added 14 mins ago
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Senior Appian Developer
Astor & Sanders
Remote, United States
- $140,000 to $180,000 USD / year
…provider headquartered in McLean, VA seeking a Senior Appian Developer. This is a full-time and hybrid position in the DMV…
Added 37 mins ago
Clinical Scientist - Job ID: 1915
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Associate/Medical Director, Clinical Development - Job ID: 1912, 1913, 1914
Ascendis Pharma
Remote, United States
- $255,000 to $265,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
Associate Director, Global Medical Writing (Publications) - Job ID: 1983
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
Global Medical Affairs Planning & Effectiveness, Content Platform Lead -Job 2033
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
Associate Project Director, GRAPS - Job ID: 2035
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
Global Medical Scientist - Job ID: 1986
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
Medical Director, Clinical Development - Job ID: 1930
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
Medical Director, Clinical Development - Job ID: 1930
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Penn Metro) - Job ID: 2055
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Penn Metro) - Job ID: 2055
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Penn Metro) - Job ID: 2055
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Penn Metro) - Job ID: 2055
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Penn Metro) - Job ID: 2055
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
Global Medical Scientist - Job ID: 2060
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
Clinical Systems Specialist - Job ID: 2061
Ascendis Pharma
Remote, United States
…Passion, we are applying our innovative TransCon® technology platform to fulfill our mission of developing new therapies that demonstrate best-in-class potential to address unmet medical…
Added 37 mins ago
Senior Manager, Statistical Programming - Job ID: 2068
Ascendis Pharma
Remote, United States
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Associate Director, Medical Affairs Statistical Sciences (Biometrics) - ID: 2069
Ascendis Pharma
Remote, United States
- $200,000 to $215,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Ohio Valley) - Job ID: 2079
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Ohio Valley) - Job ID: 2079
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Ohio Valley) - Job ID: 2079
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Ohio Valley) - Job ID: 2079
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…
Added 37 mins ago
AP
Medical Science Liaison (Ohio Valley) - Job ID: 2079
Ascendis Pharma
Remote, United States
- $175,000 to $190,000 USD / year
Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new and potentially best-in-class therapies…

Closed listing

Orion

Cybersecurity Engineer II

Houston, TX, United States

This opening has closed.

The original listing is kept below for reference.

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Job details

Experience: 4–8 years of hands-on experience in cybersecurity engineering or security operations, with demonstrated experience designing, tuning, or automating security tooling.
Posting language: English
Posted: Sep 30, 2026

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Original job description

Archived listing. The details below describe a past opening.

POSITION SUMMARY

The IT Cybersecurity Engineer II provides mid-level engineering support for the architecture, operation, automation, and continuous improvement of Orion's cybersecurity posture across on-premises, cloud, and hybrid environments. This role is responsible for evaluating and strengthening the overall security architecture, and for enhancing and automating existing security tooling to improve detection, response, and operational efficiency. The role also owns the security and integrity of Orion's SIEM and SOAR environment, ensuring the platforms that detect and respond to threats are themselves properly access-controlled, hardened, and monitored. The position holds global ownership of endpoint security review and administration, ensuring consistent policy enforcement, coverage, and hardening across the environment.

While the primary focus of this role is cybersecurity engineering, the Cybersecurity Engineer II is expected to be well-rounded across core infrastructure disciplines. The role actively cross-trains and provides backup support with the Infrastructure team and participates in shared operational and on-call responsibilities. This role works under the direction of IT leadership while partnering with the Infrastructure team, Service Desk, Applications, and business stakeholders to maintain a secure, resilient, and well-documented technology environment.

This role supports cybersecurity technologies and services including endpoint detection and response (EDR/XDR), network detection and response (NDR), SIEM and SOAR platforms, identity security, email security, vulnerability management, security monitoring and alerting, and security automation, in addition to cross-functional support of virtualization, backup, and related on-premises infrastructure.

The incumbent must support Orion's guiding beliefs and core values centered on Safety, Quality, Delivery, and Teamwork, and most importantly, built upon the all-important foundation of Integrity.

SPECIFIC RESPONSIBILITIES

Cybersecurity architecture and posture

Evaluate Orion's overall cybersecurity architecture and posture, identifying gaps and recommending improvements aligned with security best practices and industry frameworks (for example, NIST, CIS Controls, Zero Trust principles).
Partner with IT leadership to design and evolve a layered security architecture across endpoint, network, identity, email, and cloud environments, informed by findings from penetration tests, vulnerability assessments, and audits.
Translate penetration test and assessment findings into prioritized remediation plans and architectural changes, tracking implementation through to closure.

Security tooling enhancement and automation

Serve as the primary engineer responsible for enhancing, tuning, and automating Orion's core security platforms, including Darktrace and Microsoft Defender (Defender for Endpoint, Defender for Identity, Defender for Cloud Apps, Defender for Office 365).
Develop and maintain automation, scripts, and workflows (for example, PowerShell, KQL, Logic Apps/Sentinel automation, or equivalent) to streamline detection, alert triage, response actions, and reporting, reducing manual security operations effort.
Continuously tune detection rules, alert thresholds, and correlation logic to reduce false positives and improve signal quality across security platforms.
Evaluate emerging security tools and capabilities and recommend enhancements or additions to the security tooling stack.

SIEM and SOAR platform security

Own the security, access control, and configuration integrity of Orion's SIEM and SOAR environment, ensuring the platforms responsible for detection, correlation, and automated response are themselves hardened against unauthorized access, tampering, or misconfiguration.
Administer role-based access, log source onboarding, and data retention within the SIEM to protect the confidentiality and integrity of security event data used for detection, investigation, and audit evidence.
Build, test, and maintain SOAR playbooks and automated response actions, applying change control and peer review to prevent unintended or unauthorized automated actions in production.
Monitor SIEM/SOAR platform health, log ingestion completeness, and playbook execution to ensure detection and response coverage is not silently degraded.

Endpoint security ownership

Own the global review, configuration, and administration of endpoint security, across all Orion locations, devices, and business units.
Monitor endpoint security coverage, policy compliance, and protection status; identify and remediate gaps in onboarding, policy application, or protection posture.
Manage endpoint security policies, attack surface reduction rules, device configuration baselines, and vulnerability management workflows tied to endpoint protection.
Review and respond to endpoint-related security alerts and incidents, coordinating containment, remediation, and root-cause analysis.

Security monitoring, detection, and incident response

Monitor security alerts, logs, and telemetry from Darktrace, Microsoft Defender, the SIEM, and related platforms; investigate and respond to potential threats and security incidents.
Support incident response activities, including detection, containment, eradication, and post-incident documentation and lessons learned.
Perform vulnerability scanning, risk assessment, and remediation coordination across infrastructure and endpoint environments.

Compliance, audit, and governance support

Support CMMC and NIST SP 800-171 compliance activities, including control implementation, evidence collection, audit support, and remediation of identified findings.
Maintain security documentation, including architecture diagrams, standard operating procedures, playbooks, and control evidence, to support auditability and operational consistency.
Assist with security risk assessments, policy development, and control reviews in coordination with IT leadership.

Cross-training and infrastructure support

Cross-train and maintain working proficiency with core on-premises infrastructure platforms managed by the Infrastructure team, including VMware virtualization and Veeam backup and recovery.
Provide backup coverage for infrastructure operations as needed, including virtualization, backup/recovery, storage, and related on-premises systems, to reduce single points of knowledge given the size of the IT team.
Partner with the Infrastructure team on projects and changes that have security implications, ensuring security requirements are incorporated into infrastructure design and operations.

Documentation and continuous improvement

Maintain accurate technical documentation, including security architecture diagrams, configuration standards, runbooks, and change records.
Identify and communicate opportunities to improve security posture, tooling effectiveness, and operational efficiency; participate in continuous improvement initiatives.
Coordinate effectively with the Infrastructure team, Service Desk, Applications, vendors, and other stakeholders to resolve incidents, support projects, and ensure smooth handoffs.

After-hours response and operational readiness

Respond to off-hour security alerts, calls, emails, or notifications as needed to maintain security monitoring coverage and operational uptime.
Ensure incident response communications and handoffs are clear, timely, and documented.

Broader IT support and other duties

Support broader IT and security projects and perform other related administrative and technical duties as assigned by IT leadership.

POSITION REQUIREMENTS

Non-Technical

Demonstrated ability to deliver high-quality results with minimal supervision in a fast-paced environment.
Strong communication, analytical, and problem-solving skills with the ability to explain technical and security concepts to non-technical stakeholders.
Proven ability to learn new technologies and threat landscapes quickly through research, self-directed learning, and hands-on experimentation.
Strong documentation habits and attention to detail, including architecture diagrams, playbooks, and audit evidence.

Technical

Bachelor's degree in Computer Science, Information Technology, Cybersecurity, or related field, or equivalent practical experience. Relevant certifications are preferred (examples: CompTIA Security+/CySA+, Microsoft SC-200/SC-100, CEH, GIAC, or equivalent).
4–8 years of hands-on experience in cybersecurity engineering or security operations, with demonstrated experience designing, tuning, or automating security tooling.
Strong understanding of cybersecurity architecture principles and security frameworks, with experience aligning to NIST SP 800-171 and supporting CMMC compliance readiness activities.
Hands-on experience with Microsoft Defender (Endpoint, Identity, Cloud Apps, Office 365) and network detection and response platforms such as Darktrace, including tuning, automation, and reporting.
Hands-on experience administering and securing a SIEM and SOAR environment, including access control, log source management, and building/maintaining automated response playbooks.
Experience administering endpoint security at scale, including policy management, attack surface reduction, vulnerability management, and incident response.
Working proficiency with scripting and automation (for example, PowerShell, KQL) to build repeatable security workflows, detections, and reporting.
Working knowledge of virtualization and backup platforms (VMware and Veeam or equivalent) sufficient to cross-train and provide backup support with the Infrastructure team.
Proficient with standard Microsoft productivity tools (Visio, Word, Excel, Outlook, PowerPoint) for documentation, diagrams, reporting, and communication.
Experience supporting security audits, e-discovery technical requests, and handling sensitive data with confidentiality, documented procedures, and access controls is preferred.

EMPLOYEE SAFETY AND COMPLIANCE

Responsible and accountable for the incumbent's safety.
Responsible and accountable for the safety of all co-workers and any other incumbent encounters.
Authorized and obligated to stop work on any task or series of tasks whenever an unsafe condition or situation is anticipated or observed.
Complies with all applicable laws, regulations, and Company policies and procedures and is subject to appropriate disciplinary action (including dismissal) for failure to do so.
Reports any violations of applicable laws, regulations or Company policies and procedures promptly, and is subject to appropriate disciplinary action (including dismissal) for failure to do so.
All employees, current and former, must maintain confidentiality by not disclosing to others any confidential, proprietary, or trade secret information belonging to the Company.

PHYSICAL/MENTAL REQUIREMENTS

The engineer must be able to perform the job's essential functions with or without reasonable workplace accommodation.

The individual must also be able to wear and properly utilize appropriate personal protective equipment if required to work or visit the job site. This may include a hard hat, safety glasses, respirators, ear plugs, steel-toed shoes, personal flotation devices, or other equipment as required by the work performed and the location where the work is being done.

The incumbent must possess the ability to remain calm during emergencies and respond appropriately as dictated by the circumstance of the incident and as directed by the Safety Representative or other management personnel. Must be capable of evacuating the work area promptly should an emergency arise.

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