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Natera

Staff Software Engineer

Remote, United States

$152,100 - $190,100 USD

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Job details

Pay: $152,100 - $190,100 USD
Posting language: English
Posted: Nov 4, 2026

Original job description

As a Staff Software Engineer, you will lead the design, development, and maintenance of the LIMS application and related software. You will be one of the primary technical leads of the Software Engineering group, working to provide design solutions and general team leadership to other engineers and Technical Product Managers.

PRIMARY RESPONSIBILITIES:

Work closely with stakeholders and users to define requirements
Translate requirements into reliable and extensible operations-friendly applications in Python
Work with an engineering team to make key design and technical implementation decisions
Have a holistic view of processes and systems involved in taking patient samples from order to result in a multi-product clinical laboratory
Understand LIMS platform features and propose solutions that present trade-off analysis and make best use of the platform
Leverage off-the-shelf or existing functionality whenever possible so development resources can be focused on unmet needs
Integrate other enterprise systems and services to create seamless business processes.
Improve development process and procedure and evangelize best practices
Develop and maintain automated tests
Provide second-tier production support

QUALIFICATIONS:

BS degree in computer science, comparable program, or equivalent.
10+ years of overall software development experience, preferably building complex data or process management applications in production
10 + years of experience with Python
10+ years of experience with web services (REST, etc) and relational databases
Experience with front-end web programming, preferably with modern JavaScript frameworks (react, angular, etc.)
Experience in regulated environments (CLIA/CAP, HIPAA, 21 CFR Part 11, ISO 13485, IEC 62304, GxP) and software validation practices
Strong relational database skills including database design, migrations, and optimization (PostgreSQL or MySQL preferred)
Demonstrated experience leading the replacement or consolidation of legacy or disparate systems into a unified platform

NICE TO HAVE:

Experience building and configuring LIMS or other laboratory workflow software, and implementing external applications and integrations with a LIMS systems, ideally in a clinical, genomics, or high-throughput setting
Experience integrating laboratory instruments and automation

KNOWLEDGE, SKILLS, AND ABILITIES:

Python (FastAPI, Pydantic, SQLAlchemy or similar ORM)
JavaScript / TypeScript
Relational Database and SQL Programming, prefer PostgreSQL or MySQL
REST APIs and Event-Driven Microservice Architecture
Messaging and event streaming (SQS/SNS, Pub/Sub, Kafka)
Infrastructure-as-code (Terraform, etc.)
Docker or container-oriented technologies

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. Remote USA

$152,100 - $190,100 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:

BBB announcement on job scams
FBI Cyber Crime resource page

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More about this job

Skills

LIMS
Team leadership
Python
Business processes
Computer science
Software development
Web programming
JavaScript
PostgreSQL
MySQL
Workflow
TypeScript
SQL
API development
Apache Kafka
Infrastructure as code
IBM Terraform
Docker

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