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Natera

Senior Manager, Software Engineering - Case Management Platform

Remote, United States

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Job details

Experience: 8+ years of professional software development experience, with meaningful time building complex data or process-management applications
Posting language: English
Posted: Oct 30, 2026

Original job description

Senior Manager, Software Engineering - Case Management Platform

POSITION TITLE: Senior Manager, Software Engineering - Case Management Platform (CMP)

POSITION LOCATION: San Carlos, CA, Austin, TX, or Remote, USA

POSITION SUMMARY

Natera is seeking a hands-on, technically deep Senior Manager of Software Engineering to lead our Case Management Platform (CMP) Core team. CMP is the technical backbone that moves patient cases from order to result across Natera's oncology, women's health, and organ health product lines - software whose reliability translates directly into turnaround time, lab efficiency, and patient outcomes.

This is explicitly not a people-management-only role. You will integration into an existing platform application department and build a new high leverage squad with a distinct mission to bridge Natera's commerce and fulfillment domains. With a small initial footprint, you are expected to be in the code: setting architectural direction, writing and reviewing code, driving production support, and modeling the engineering standard. As the team grows, you will rebalance your time toward leadership, hiring, and strategy - but hands-on technical credibility is a permanent requirement of this role.

We are looking for an agent of change. CMP is pushing hard on AI-native ways of working, mission-based team structure, and InnerSource stewardship. You will not just adopt these shifts - you will drive them.

RESPONSIBILITIES

Lead technically

Set and defend the architectural direction for your scope; make the hard trade-off calls and own the outcomes
Write production code, review PRs, and participate in production incident response alongside the team
Drive design reviews; raise the technical bar through example, not memo
Own the full SDLC for your systems - conception, design, implementation, test, release, operation, and sunset

Manage and grow people

Hire and develop top performers; recruit for attitude as aggressively as for aptitude
Hold regular 1:1s, deliver direct feedback with radical candor, and address underperformance quickly and respectfully
Guide career development; create real ownership opportunities and delegate decisions, not just tasks
Build a diverse, high-trust team that reflects the users and patients we serve

Drive the AI-native transformation

Treat AI as core to how the team builds, delivers, and operates - not an experiment on the side
Champion the adoption of AI coding tools, agent orchestration, and AI-assisted operations across your team and influence peer teams to follow
Measure and communicate the leverage AI is creating in your org; retire practices that no longer earn their keep

Partner across the business

Act as the primary technical point of contact for product management, commerce stakeholders, lab operations, and adjacent engineering teams
Build and maintain a working relationship with lab managers, lab supervisors, and commerce leaders - understand their world firsthand
Translate business priorities into engineering plans and translate engineering realities into options business leaders can act on

Manage delivery

Own estimates, scope, dependencies, risks, and delivery for your team's commitments
Run lean, outcome-oriented ceremonies; prefer visible work and short feedback loops over heavy process
Facilitate collaboration and remove blockers; escalate honestly and early

Effect change

Lead the evolution of our ways of working
Propose and drive improvements beyond the walls of your immediate team

QUALIFICATIONS

BS or MS in Computer Science or equivalent experience
8+ years of professional software development experience, with meaningful time building complex data or process-management applications
3+ years leading engineering teams, with a track record of hiring, developing, and retaining strong engineers
Demonstrated hands-on technical ability - recent experience writing production code, leading design reviews, and troubleshooting production issues as a manager, not only as an individual contributor
Strong fluency in Java or another object-oriented language, modern cloud infrastructure (AWS preferred, including Lambda and other stateless/serverless patterns), relational databases, and distributed systems
Demonstrated adoption of AI-assisted development, agent-based workflows, or similar modern engineering practices - and the ability to make others productive with them
Experience partnering with product management, operations, and business stakeholders in a matrixed environment
Excellent written and verbal communication; comfort operating across time zones with distributed and offshore teammates
Experience in biotech, healthcare, or another regulated industry is a strong plus

KNOWLEDGE, SKILLS, AND ABILITIES

Hands-on coding, design, and architecture skills - currently practiced, not historical
Deep understanding of software architecture and the full SDLC in a regulated environment
Proven record of managing highly effective, mission-oriented teams and building leadership bench strength beneath you
Comfort diagnosing production problems at all levels - from triage and workaround through root cause and prevention
Expertise building scalable, resilient distributed systems on AWS, with a bias toward simple, stateless, event-driven designs
Strong product sense; able to challenge requirements and reshape the problem when that's the better answer
Extreme ownership: keeps promises, closes loops, and models the behavior expected of the team
"Yes if" attitude - focused on finding paths forward and making constraints explicit
Humble, direct, and resilient; gives and receives feedback well
Commitment to diversity, inclusion, and building teams where people do their best work

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:

BBB announcement on job scams
FBI Cyber Crime resource page

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