Jobs in the United States

25+ jobs

Save this search

Added 24 mins ago
Infection Preventionist II
UCM
Chicago, IL · IL
…infection surveillance, implementation, project management, process improvement, identification and follow-up of significant pathogens (i.e., perform pulse-field gel electrophoresis), and…
Added 49 mins ago
Senior Product Data Scientist, Pixel Growth, Google Store
Google
Mountain View, CA
Share Senior Product Data Scientist, Pixel Growth, Google Store
Added 1 hour ago
A
Scientist
Actalent
Wilson, NC
- $50 to $55 USD / hour
Job Title: Senior Scientist Analytical Method Transfer and Quality ControlJob DescriptionThis Senior Scientist role supports a pharmaceutical organization specializing in sterile injectable…
Added 1 hour ago
A
Principal Scientist I, Biologics Drug Product Development
AbbVie
North Chicago, IL
- $124,500 to $236,500 USD / year
AbbVie is seeking a highly motivated candidate for the position of Senior Scientist II / Principal Scientist I, located in North Chicago, IL. We are seeking an accomplished scientist with a…
Added 2 hours ago
SR
Senior Scientist II, Upstream Process Development and MSAT
Scholar Rock
Cambridge, MA
- $155,000 to $195,000 USD / year
The Technical Operations Organization at Scholar Rock is seeking a scientifically accomplished and motivated scientist in the Upstream Process Development and MSAT group. The successful…
Added 2 hours ago
BV
Senior Data Scientist
Bright Vision Technologies
Remote, United States
- $160,000 to $180,000 USD / year
We are seeking an accomplished Senior Data Scientist to design, develop, deploy, and optimize enterprise-grade data science and machine learning solutions that support strategic business…
Added 3 hours ago
SI
Senior Scientist, Downstream Process Development R&D
Seagen Inc
WA
- $93,600 to $156,000 USD / year
A Senior Scientist (R4) position is available in the Downstream Process Development group within Bioprocess R&D. The successful candidate will have strong laboratory research experience and…
Added 7 hours ago
Senior Data Scientist
Jobgether
Remote, United States
As a Senior Data Scientist, you will play a strategic role in developing advanced forecasting models and machine learning solutions to support business planning and revenue growth. You will…
Added 14 hours ago
Senior Research Scientist, Battlespace Awareness
Anduril Industries
Waltham, MA · Broomfield, CO
A Senior Research Scientist at Anduril should possess an M.S. or Ph.D. in Applied or Computational Mathematics, Electrical Engineering, Computer Science, Controls and Dynamical Systems,…
Added 15 hours ago
Senior Scientist
ThermoFisher Scientific
Gaithersburg, MD
…goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of…
Added 15 hours ago
Senior Research Scientist, Battlespace Awareness
Anduril Industries
Broomfield, CO
A Senior Research Scientist at Anduril should possess an M.S. or Ph.D. in Applied or Computational Mathematics, Electrical Engineering, Computer Science, Controls and Dynamical Systems,…
Added 17 hours ago
Senior Cybersecurity AI Solutions Engineer
NVIDIA Corporation
North District, IL
…using NVIDIA Data Center Simulators (DSX AIR). Work with data scientist for fine-tuning state-of-the-art AI models - such as NVIDIA Nemotron, and automating complex pipelines. The ideal…
Added 18 hours ago
ST
Senior Director, Biomarker and Translational Sciences
Seismic Therapeutic Inc
Watertown, MA
- $220,000 to $280,000 USD / year
…people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that. This is a terrific…
Added 1 day ago
Principal / Sr. Principal Scientist - Molecular Biology & Protein Expression
Lilly
San Diego, CA
The Principal Scientist / Senior Principal Scientist in Molecular Biology & Protein Expression will join a centralized molecular biology and protein expression platform team within Lilly…
Added 1 day ago
Research Intern (Academic Credit) - Department of Neurology - Per Diem (On-site)
Cedars-Sinai
Los Angeles, CA
…investigations. Under direct supervision from the assigned Postdoctoral Scientist, senior-level Research Associate and/or Principal Investigator, the intern will be provided with basic…
Added 1 day ago
A
Program Manager, MES
AbbVie
Tempe, AZ
- $109,500 to $208,500 USD / year
Assemble and lead matrixed cross-functional teams comprised of scientist and engineers responsible for all operational aspects of process development, manufacturing, quality assurance and…
Added 1 day ago
Oligonucleotide Senior Scientist
Eurofins US Network
Louisville, KY
Oligonucleotide Senior Scientist Include but are not Limited to the Following:
Added 1 day ago
Principal / Sr. Principal Scientist - Molecular Biology & Protein Expression
Eli Lilly and Company
United States
The Principal Scientist / Senior Principal Scientist in Molecular Biology & Protein Expression will join a centralized molecular biology and protein expression platform team within Lilly…
Added 1 day ago
Senior Manager (Safety Ops/Safety Scientist)
Bristol Myers Squibb
Princeton, NJ
Oversee processes, training and compliance of external case management vendors, CAPA development.
Added 1 day ago
Senior Scientist - Analytical Chemist
Eurofins US Network
Saint Charles, MO
Are you looking to grow your career in analytical chemistry? Come join our growing team! The Scientist II – Analytical Chemist will support the Eurofins Discovery business in contract…
Added 2 days ago
Lead Data Scientist
MetLife
Cary, NC
The Lead Data Scientist is crucial to DnA USB's Engagement Strategy team, creating Machine Learning and AI solutions to support marketing campaigns and business engagement. You will provide…
Added 2 days ago
Staff Scientist, Cell Lab (GMP)
ThermoFisher Scientific
Middleton, WI
The Staff Scientist provides expert-level technical leadership within the laboratory as a senior scientific contributor and recognized technical authority. This role delivers oversight for…
Added 2 days ago
Analytical Associate Scientist
MILLIPORESIGMA
MADISON, WI
Added 2 days ago
Environmental Scientist - Waste Recycling & Disposal
WEC Energy Group
Milwaukee, WI
WEC Business Services LLC, a subsidiary of WEC Energy Group, is seeking a Environmental Scientist - Waste Recycling & Disposal (Environmental Consultant) in our Milwaukee, Wisconsin…
Added 2 days ago
M
Senior Applied Scientist
Microsoft
WA · Redmond, WA · Redmond
- $119,800 to $261,000 USD / year
We are looking for a Senior Applied Scientist to help us deliver breakthrough applied machine learning and information retrieval solutions at enterprise scale. This role is a unique…

Microsoft

Senior Applied Scientist

WA, United States
Redmond, WA, United States
Redmond, United States

$119,800 to $261,000 USD / year

Apply About employer

Applications open in a new tab.

Job details

Pay: $119,800 to $261,000 USD / year
Apply by: Apr 28, 2027
Posting language: English
Posted: Oct 30, 2026

Original job description

Overview

The CASQ (Copilot, Agents, Search Quality) Search Relevance team is at the forefront of delivering world-class search quality across Microsoft's ecosystem. We are the driving force behind the relevance of results in Copilot Search experiences and serve as the core retrieval layer in the RAG architecture powering Bizchat (CoPilot Chat). Our impact also extends to maintaining high search quality across traditional endpoints like Outlook, Teams, and SharePoint Search. Our team thrives at the intersection of innovation and applied machine learning.

We are looking for a Senior Applied Scientist to help us deliver breakthrough applied machine learning and information retrieval solutions at enterprise scale. This role is a unique opportunity to apply state-of-the-art techniques-including dense retrieval, hybrid search, multilingual large language models (LLMs), RAG (Retrieval-Augmented Generation), and transformer-based re-ranking models and agentic search-to solve complex challenges in Copilot-driven enterprise search.

As a Senior Applied Scientist, you'll be responsible for delivering mission-critical innovations that directly improve Copilot experiences such as:

Agentic Search in modern orchestrator architectures
Adapting advanced vector search algorithms (e.g., FAISS, ANN, ScaNN) for enterprise-scale semantic retrieval
Improving classic and neural keyword search quality through deep language understanding
Designing and training relevance models, including LLM fine-tuning and learning-to-rank (LTR) approaches
Building robust evaluation pipelines using offline metrics and online A/B experimentation
Driving cross-org collaboration with platform partners, other applied science teams, and product teams across time zones
Setting vision and directions for agentic search in CoPilot Chat inspired by state-of-the-art and data-driven analysis

This role requires a mix of technical depth, strategic execution, and people management to shape the next generation of AI-powered search experiences. Microsoft’s mission is to empower every person and every organization on the planet to achieve more. As employees we come together with a growth mindset, innovate to empower others, and collaborate to realize our shared goals. Each day we build on our values of respect, integrity, and accountability to create a culture of inclusion where everyone can thrive at work and beyond.

Responsibilities

Drive end-to-end applied science projects: From ideation and design to implementation, experimentation, and shipping, you will lead high-impact projects that directly improve Copilot Chat, Copilot Search, and BizChat experiences. This includes identifying search and relevance gaps, formulating innovative hypotheses, and delivering scalable solutions.
Inspire help to grow a high-performing applied science team: mentor, and empower a team of applied scientists-owning their technical direction, project execution, and career development. You will guide day-to-day work, ensure scientific and engineering rigor, and be accountable for the team's output and impact.
Innovate with scientific rigor: Invent and apply cutting-edge techniques in machine learning, natural language processing, and information retrieval to address real-world challenges at enterprise scale. You will design novel approaches for improving retrieval, ranking, query understanding, and semantic search in Copilot systems.
Document, share, and amplify learnings: Promote a culture of transparency and innovation by capturing experimental results, documenting methodology, and publishing internal learnings. You'll drive knowledge sharing that enables broader impact across the organization.
Translate business goals into scientific strategy: Partner closely with product and business stakeholders to align team efforts with high-priority objectives. You will translate ambiguous product requirements into clear, data-driven, and technically feasible directions.
Collaborate across organizations and time zones: Work cross-functionally with platform engineering teams, peer science orgs, and product managers to ensure alignment, resolve dependencies, and unblock progress. You'll be a key bridge between applied science innovation and product delivery.
Embody our Culture and Values

Qualifications

Required Qualifications:

Bachelor's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 4+ years related experience (e.g., statistics predictive analytics, research)
OR Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 3+ years related experience (e.g., statistics, predictive analytics, research)
OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 1+ year(s) related experience (e.g., statistics, predictive analytics, research)
OR equivalent experience.

Other Requirements:

Ability to meet Microsoft, customer and/or government security screening requirements are required for this role. These requirements include but are not limited to the following specialized security screenings:

Microsoft Cloud Background Check: This position will be required to pass the Microsoft Cloud background check upon hire/transfer and every two years thereafter.

Preferred Qualifications:

Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 9+ years related experience (e.g., statistics, predictive analytics, research)
OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 6+ years related experience (e.g., statistics, predictive analytics, research)
OR equivalent experience.
5+ years experience in applied science projects from ideation to production-in high-scale environments such as search, recommendation, or conversational AI.
5+ years experience in data analysis at scale, including working with logs, telemetry, and large datasets to uncover behavioral patterns, build evaluation datasets, and derive insights.
6+ years experience creating publications (e.g., patents, libraries, peer-reviewed academic papers).
2+ years experience presenting at conferences or other events in the outside research/industry community as an invited speaker.
5+ years experience conducting research as part of a research program (in academic or industry settings).
5+ years experience developing and deploying live production systems, as part of a product team.
5+ years experience developing and deploying products or systems at multiple points in the product cycle from ideation to shipping.
Experience in search and ranking systems, semantic retrieval, and information retrieval at scale.
Applied experience with state-of-the-art sparse and dense retrieval and ranking techniques.
Experience with RAG (Retrieval-Augmented Generation) architectures using LLMs such as OpenAI GPT, T5, or Llama.
Experience with Fine-tuning or prompt engineering of large-scale language models for query rewriting, summarization, and document reranking.
Familiarity with hybrid search strategies, learning-to-rank (LTR) frameworks, and evaluation methodologies for IR systems (offline metrics, A/B testing, relevance judgments).
5+ years experience in applied science projects from ideation to production-in high-scale environments such as search, recommendation, or conversational AI.
5+ years experience in data analysis at scale, including working with logs, telemetry, and large datasets to uncover behavioral patterns, build evaluation datasets, and derive insights.
6+ years experience creating publications (e.g., patents, libraries, peer-reviewed academic papers).
2+ years experience presenting at conferences or other events in the outside research/industry community as an invited speaker.
5+ years experience conducting research as part of a research program (in academic or industry settings).
5+ years experience developing and deploying live production systems, as part of a product team.
5+ years experience developing and deploying products or systems at multiple points in the product cycle from ideation to shipping.
Experience in search and ranking systems, semantic retrieval, and information retrieval at scale.
Applied experience with state-of-the-art sparse and dense retrieval and ranking techniques.
Experience with RAG (Retrieval-Augmented Generation) architectures using LLMs such as OpenAI GPT, T5, or Llama.
Experience with Fine-tuning or prompt engineering of large-scale language models for query rewriting, summarization, and document reranking.
Familiarity with hybrid search strategies, learning-to-rank (LTR) frameworks, and evaluation methodologies for IR systems (offline metrics, A/B testing, relevance judgments).

#CAP #Copilot

Applied Sciences IC4 - The typical base pay range for this role across the U.S. is USD $119,800 - $234,700 per year. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $160,200 - $261,000 per year.

Certain roles may be eligible for benefits and other compensation. Find additional benefits and pay information here: https://careers.microsoft.com/us/en/us-corporate-pay

This position will be open for a minimum of 5 days, with applications accepted on an ongoing basis until the position is filled.

Microsoft is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship, color, family or medical care leave, gender identity or expression, genetic information, immigration status, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran or military status, race, ethnicity, religion, sex (including pregnancy), sexual orientation, or any other characteristic protected by applicable local laws, regulations and ordinances. If you need assistance with religious accommodations and/or a reasonable accommodation due to a disability during the application process, read more about requesting accommodations.

Apply About employer

More about this job

Skills

Microsoft Outlook
Microsoft Teams
Microsoft SharePoint
Team leadership
Natural language processing
Product comprehension
Statistics
Computer science
Computer engineering
Research
Data analysis

Report this job