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Added 2 mins ago
Senior Platform Engineer - NBA
Humana
Indianapolis, IN
The Senior Platform Engineer keeps the entire NBA platform healthy, reliable, and maintainable for the long term. You develop a working understanding of every layer of the technology stack…
Added 2 mins ago
Senior Full Stack Engineer - NBA
Humana
Indianapolis, IN
The Senior Full Stack Engineer builds and evolves the NBA platform's Action Library and Command Center experience, the operational system used by business and program teams to create,…
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Senior Decision Intelligence Engineer
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Indianapolis, IN
The Senior Machine Learning Engineer, Decision Intelligence is a hands-on individual contributor responsible for building, deploying, and operating ML and decisioning pipelines for the NBA…
Added 2 mins ago
Associate VP Network Engineer
Deloitte
Indianapolis, IN
…that improve agility, resilience, and security while reducing operational cost through automation. Our practitioners work across enterprise campus, data center, and cloud-interconnected…
Added 2 mins ago
Lead Integration Engineer II
Deloitte
Indianapolis, IN
US-E - Consulting - Lead Integration Engineer II - AI & Engineering/EaaS
Added 2 mins ago
AI Engineer II
Deloitte
Indianapolis, IN
…significant impact on our clients' success. We are hiring an AI Engineer to build and operate the data, features, and GenAI foundations that power Human Capital AI products and analytics.…
Added 2 mins ago
AI Engineer III
Deloitte
Indianapolis, IN
…significant impact on our clients' success. We are hiring an AI Engineer to build and operate the data, features, and GenAI foundations that power Human Capital AI products and analytics.…
Added 3 mins ago
EG
Senior Data Engineer
Eliassen Group
Indianapolis, IN
- $101,000 to $161,800 USD / year
Our client seeks a Senior Data Engineer to own the governed transformation layer end-to-end. The role will design and build Snowflake transformation layers, migrate legacy SQL views and…
Added 18 mins ago
Software Engineering Group Mgr - Kubernetes CaaS Platform
PNC
Birmingham, AL
…Engineering Group Mgr. leader to lead the strategy, architecture, and operational excellence of Kubernetes-based container platforms. The successful candidate will be instrumental in…
Added 18 mins ago
EG
Senior Data Engineer
Eliassen Group
Montgomery, AL
- $101,000 to $161,800 USD / year
Our client seeks a Senior Data Engineer to own the governed transformation layer end-to-end. The role will design and build Snowflake transformation layers, migrate legacy SQL views and…
Added 31 mins ago
EG
Senior Data Engineer
Eliassen Group
Lansing, MI
- $101,000 to $161,800 USD / year
Our client seeks a Senior Data Engineer to own the governed transformation layer end-to-end. The role will design and build Snowflake transformation layers, migrate legacy SQL views and…
Added 33 mins ago
Senior Infrastructure Engineer
Jobgether
Remote, United States
This position is listed on behalf of a partner company, which manages all applications and next steps. Our partner is looking for a Senior Infrastructure Engineer based in the United States.
Added 46 mins ago
EG
Senior Data Engineer
Eliassen Group
Boise, ID
- $101,000 to $161,800 USD / year
Our client seeks a Senior Data Engineer to own the governed transformation layer end-to-end. The role will design and build Snowflake transformation layers, migrate legacy SQL views and…
Added 50 mins ago
Lead Engineer, Autonomous Lab Platforms
Genentech
South San Francisco, CA
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Added 51 mins ago
EG
Senior Data Engineer
Eliassen Group
Juneau, AK
- $101,000 to $161,800 USD / year
Our client seeks a Senior Data Engineer to own the governed transformation layer end-to-end. The role will design and build Snowflake transformation layers, migrate legacy SQL views and…
Added 56 mins ago
EG
Senior Data Engineer
Eliassen Group
Santa Fe, NM
- $101,000 to $161,800 USD / year
Our client seeks a Senior Data Engineer to own the governed transformation layer end-to-end. The role will design and build Snowflake transformation layers, migrate legacy SQL views and…
Added 1 hour ago
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Practice Director, Data & AI
Jobgether
Remote, United States
- $200,000 to $230,000 USD / year
The Practice Director, Data & AI will lead and scale an integrated Data & AI practice, driving its strategic direction, commercial growth, operational excellence, and technical…
Added 1 hour ago
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Principal Core Infrastructure Engineer-Network Capacity
Oracle
Nashville, TN
- $114,600 to $234,600 USD / year
In this role, you will develop reliable, secure, and data-intensive services used by engineering and planning teams. You will work closely with Software Developers, Machine Learning…
Added 1 hour ago
EG
Senior Data Engineer
Eliassen Group
Nashville, TN
- $101,000 to $161,800 USD / year
Our client seeks a Senior Data Engineer to own the governed transformation layer end-to-end. The role will design and build Snowflake transformation layers, migrate legacy SQL views and…
Added 1 hour ago
O
Principal Network Developer
Oracle
Nashville, TN
- $102,300 to $209,500 USD / year
As a Principal Network Engineer, you will lead the design, deployment, operation, and optimization of large-scale RDMA/RoCE network fabrics across OCI’s global cloud infrastructure. You…
Added 1 hour ago
O
Principal Network Developer
Oracle
Nashville, TN
- $102,300 to $209,500 USD / year
As a Principal Network Engineer, you will lead the design, deployment, operation, and optimization of large-scale RDMA/RoCE network fabrics across OCI’s global cloud infrastructure. You…
Added 2 hours ago
Senior Platform Engineer - NBA
Humana
Montpelier, VT
The Senior Platform Engineer keeps the entire NBA platform healthy, reliable, and maintainable for the long term. You develop a working understanding of every layer of the technology stack…
Added 2 hours ago
Senior Full Stack Engineer - NBA
Humana
Montpelier, VT
The Senior Full Stack Engineer builds and evolves the NBA platform's Action Library and Command Center experience, the operational system used by business and program teams to create,…
Added 2 hours ago
Senior Decision Intelligence Engineer
Humana
Montpelier, VT
The Senior Machine Learning Engineer, Decision Intelligence is a hands-on individual contributor responsible for building, deploying, and operating ML and decisioning pipelines for the NBA…
Added 2 hours ago
EG
Senior Data Engineer
Eliassen Group
Montpelier, VT
- $101,000 to $161,800 USD / year
Our client seeks a Senior Data Engineer to own the governed transformation layer end-to-end. The role will design and build Snowflake transformation layers, migrate legacy SQL views and…

Lilly

Sr Principal Engineer - Data

Indianapolis, IN, United States

$129,000 - $211,200

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Job details

Pay: $129,000 - $211,200
Posting language: English
Posted: Sep 29, 2026

Original job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work - but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

We are seeking an experienced Senior Principal Data, Analytics & AI Engineer to join the Global DIA team within MQ Tech at Lilly. This role sits at the intersection of data engineering, supply chain domain expertise, and applied AI. You will architect the near-real-time data foundations that AI agents reason over and lead the design of the agents themselves - multi-agent workflows that read across manufacturing and supply chain systems, correlate signals that today sit in disconnected platforms, and put clear, actionable insight in front of the people running the line and the network.

This is a senior principal, hands-on delivery role with technical leadership expectations. You will own solutions end to end, set technical direction for correlating supply chain and manufacturing data through data modernization and agentic AI, and mentor engineers on the team. The solutions you build reach production and are used every shift, bringing transparency and decision support to Lilly's Supply Chain and Manufacturing operations.

Job Responsibilities

Technical leadership and architecture

Own the technical design and architecture for agentic AI and data modernization solutions across the Global Supply Chain and MQ landscape, from problem framing through production support.
Set standards and reusable patterns for cloud based data modeling, pipeline design, agent orchestration, and evaluation that other engineers build on.
Mentor and provide technical guidance to junior and mid-level engineers; lead code and design reviews.
Partner with senior business stakeholders and IT leadership to shape roadmaps, sequence delivery, and make build/buy trade-offs; direct and hold accountable external vendor and partner teams.

Supply chain data domain and analytics

Develop and apply deep working knowledge of Global Supply Chain data domains - material master, BOM and recipe, procurement, inventory and stock movements, production orders and batch execution, planning and scheduling, warehouse management, transportation management, distribution and logistics, quality and deviations.
Work fluently across SAP (S/4HANA, ECC, BW/4HANA - master data, MM, PP, QM, SD, and IBP) and SHARP , translating source-system semantics into trusted, business-ready data models.
Bring an informed point of view on end-to-end supply chain processes - S&OP, MRP, plan-to-produce, source-to-pay, order-to-cash, capacity and inventory management - and the analytics that support them, including service level, inventory turns, cycle time, schedule adherence, and supply risk.
Correlate supply chain and manufacturing data - linking ERP, planning, MES, historian, and quality data across systems and time - to produce integrated business solutions that answer questions no single system can, using data modernization and agentic AI.

Agentic AI and machine learning

Closely collaborate with the business & other global teams on agentic solution design, requirement gathering, solution development and delivery to drive meaningful business value
Design, build, and deploy AI agents and multi-agent workflows that automate analysis and decision support across manufacturing and supply chain use cases - including prompt engineering, tool and function calling, agent orchestration, and retrieval-augmented generation (RAG) over technical documents and operational data.
Define how agent performance is measured and improved: test scenarios, evaluation criteria, accuracy and hallucination monitoring, user feedback loops, agent observability, and guardrails that keep agent behavior safe, grounded, and within scope.
Implement, test, and deploy machine learning and predictive models into production, ensuring performance, scalability, and interpretability.

Data engineering and delivery

Design, build, and maintain scalable, reliable data pipelines using modern ETL/ELT tooling to ingest, process, and transform large datasets from diverse operational and enterprise sources in support of advanced analytics, reporting, and agentic AI.
Lead data modernization efforts - migrating and re-platforming legacy supply chain reporting and data assets onto modern lakehouse and cloud architectures.
Monitor and troubleshoot data quality and agent behavior issues, ensuring data integrity and reliability across all platforms.
Develop and maintain documentation for data architecture, data flows, agent designs, prompts, model choices, and deployments to support maintainability, validation, and GxP/CSV requirements.
Ensure compliance with all relevant data privacy, security, and responsible AI requirements.
Stay abreast of the fast-moving agentic AI and data engineering landscape and bring practical, proven advances into the team's work.

Basic Qualifications

Bachelor’s in Computer Science, Engineering, Data Science, Statistics, Supply Chain, or related field with 8+ years in data engineering, analytics, or AI/ML, with hands-on production Gen-AI/agentic app delivery.
Experience in supply chain/manufacturing data, hands-on SAP (S/4HANA/ECC, BW/4HANA) , SHARP, MES and related data and analytics experience.
Hands-on advanced statistical, machine learning, LLM/agentic app development: prompt engineering, tool/function calling, RAG, vector search/embeddings, multi-step workflows.
Deep knowledge of agent frameworks (LangChain, LangGraph, or equivalent) and production LLM APIs (OpenAI, Azure OpenAI, Anthropic, Bedrock); Azure/AWS/Databricks.
Advanced Python (preferred); SQL,Java/Scala/R a plus, PowerBi/Tablue, Web Apps etc
Experience in end-to-end developing production grade analytics systems.

Preferred Qualifications

Masters in Computer Science, Engineering, Data Science, Statistics, Supply Chain, or related field with 5+ years in data engineering, analytics, or AI/ML, with hands-on production Gen-AI/agentic app delivery.
Experience in pharmaceutical, life sciences, or other regulated manufacturing supply chains.
Track record of taking multiple AI or agentic solutions through to production, including evaluation, monitoring, and iteration after go-live.
Strong command of manufacturing processes and metrics (OEE, downtime, yield, batch performance, right-first-time) alongside supply chain metrics.
Experience with supply chain planning software (SAP IBP, Kinaxis, o9) and IoT/streaming operational data.
Exposure to manufacturing data sources such as historians (OSI PI), MES/TrakSYS, PMX, or LIMS.
Experience working in a GxP-regulated environment, including CSV and validation practices.
Experience with data visualization tools (Power BI preferred).
Applied knowledge of responsible AI practices: model risk, bias, explainability, and data privacy.
Experience leading globally distributed teams or vendor partners.
Databricks, AWS or Azure certifications.

Additional Information:

· Position is located in Indianapolis, Indiana

· Full time position 5 days per week onsite

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$129,000 - $211,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

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