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Added 3 hours ago
Principal / Sr Principal Engineer Electrical
Northrop Grumman
Colorado Springs
Northrop Grumman Space Systems is seeking a Principal or Sr Principal Electrical Engineer to join the Radar Integrated Product Team (IPT) supporting the design and development of a new…
Added 4 hours ago
Principal Software Automation/Test Engineer
Palo Alto Networks, Inc.
CA
- Set the bar and mentor. Raise engineering standards through design reviews, code reviews, and best practices. Mentor senior and staff engineers, and influence technical direction across…
Added 5 hours ago
Principal Engineer - FPGA/ASIC Design
Rolls-Royce
United States
Job Title: Principal Engineer - FPGA/ASIC Design
Added 6 hours ago
Associate Field Application Engineer - AMD
Avnet US
San Jose, CA
Entry-level electrical or computer engineer who, as a member of the sales and technical team, helps drive customer adoption of AMD adaptive SoCs and FPGAs. The Associate FAE supports…
Added 6 hours ago
Associate Field Application Engineer - AMD
Avnet US
Wilmington, MA
Entry-level electrical or computer engineer who, as a member of the sales and technical team, helps drive customer adoption of AMD adaptive SoCs and FPGAs. The Associate FAE supports…
Added 7 hours ago
Electrical Engineer (Mid to Senior)
Eclipse Space Technologies Corp.
Seattle, WA
As an Electrical Engineer at Eclipse Space Technologies Corporation, you’ll own the architecture, design, and delivery of critical electronics that enable communication and coordination…
Added 8 hours ago
Principal Software Architect - Emerging Technologies
Granicus
Remote, United States
…architecture, agent orchestration patterns, the eval-driven development discipline, and a continuous integration and delivery system engineered for a high volume of autonomous agent pull…
Added 8 hours ago
Principal Engineer - AI/ ML - Home Broadband Solutions
Verizon Data Services LLC
Irving, TX
As a Principal Engineer - AI/ML Engineering for Verizon Home Broadband, you will own the architecture, engineering standards and AI strategy of its device-telemetry analytics platform…
Added 9 hours ago
Principal IT Architect
NextEra Energy
Juno Beach, FL
The Principal IT Architect will serve as the senior technical leader for applications and platforms supporting NEET Transmission and NEER Development. This role will partner with Enterprise…
Added 10 hours ago
TL
Solution Architect Product Engineer/AI
The LaunchCode Foundation
Remote, United States
- $195,000 to $210,000 USD / year
As an AI Product Engineering Principal Architect, you are the senior technical leader responsible for driving the design, delivery, and execution of complex, enterprise-grade AI solutions.…
Added 10 hours ago
Principal Embedded Software Engineer (FPGA / Firmware)
Insight Global
Aliso Viejo, CA
We are seeking a Principal Embedded Software Engineer to lead the design and development of embedded firmware and FPGA-based solutions supporting next-generation hardware platforms. This…
Added 11 hours ago
M
Principal Software Engineer
Microsoft
WA · Redmond, WA · Redmond
- $142,800 to $304,200 USD / year
We are looking for a Principal Software Engineer to help us deliver the next generation of the Agent Platform. You will design, develop, and harden core platform capabilities, real‑time…
Added 11 hours ago
Principal / Sr Principal Engineer Electrical
CORP-Corporate Office
United States
Northrop Grumman Space Systems is seeking a Principal or Sr Principal Electrical Engineer to join the Radar Integrated Product Team (IPT) supporting the design and development of a new…
Added 13 hours ago
Principal Engineer - Software
Arena Technical Resources, LLC
Oshkosh, WI
The Principal Engineer – Software develops embedded software for various
Added 14 hours ago
I
Director of Engineering - A&D
IFS
Remote, United States
- $180,000 to $210,000 USD / year
Technical depth: significant experience in software engineering, with a track record of operating at Principal Engineer or Architect level - system design, cross-team architectural thinking…
Added 14 hours ago
Principal Systems Engineer / Sr. Principal Systems Engineer
Northrop Grumman
Roy, UT
Northrop Grumman Defense Systems currently has an opening for a Principal Systems Engineer/Sr. Principal Systems Engineer . This position is located in Roy, UT and will support the Sentinel…
Added 15 hours ago
Sr Configuration Analyst/Manager, Mechanical Engineering, Configuration Management
Amazon
Redmond, WA
We are seeking an experienced Configuration Change Analyst/Manager with deep expertise in Configuration Management and Systems Engineering to join the Engineering Practice & Configuration…
Added 16 hours ago
Principal/Sr Principal System Engineer (AHT)
Northrop Grumman
Azusa, CA
Northrop Grumman is seeking Principal Systems Engineers/Sr. Principal Systems Engineers. This position will be located at our Space sector in Azusa, CA. The qualified candidate will become…
Added 16 hours ago
Software Quality Engineer/ Prin Software Quality Engineer
Northrop Grumman
Palmdale, CA · San Diego, CA
Northrop Grumman Aeronautics Systems sector is seeking a Software Quality Engineer/ Principal Software Quality Engineer to join our team of qualified, diverse individuals located in Rancho…
Added 18 hours ago
Sr Principal Engineer - Data
Lilly
Indianapolis, IN
We are seeking an experienced Senior Principal Data, Analytics & AI Engineer to join the Global DIA team within MQ Tech at Lilly. This role sits at the intersection of data engineering,…
Added 21 hours ago
Technical Leader - AIOps & Agentic Platform
Cisco
San Jose, CA
In this role, you will be a key senior engineer and technical leader building our next-generation AIOps and Agentic Operations Platform. You will design and implement AI-powered operational…
Added 1 day ago
Sentinel Principal / Sr Principal Manufacturing Engineer
Northrop Grumman
Vandenberg Air Force Base, CA
…engineering solutions to deploy and deliver a state-of-the-art weapon system to our customer. This position requires a highly motivated self-starter with knowledge in the fabrication,…
Added 1 day ago
Electrical Engineer - Hardware 2/3
Northrop Grumman
San Diego, CA
Northrop Grumman Aeronautics Systems has an opening for a Electrical Engineer - Hardware 2/3 to join the team of qualified individuals. Position is located in San Diego, CA.
Added 1 day ago
Sentinel - Systems Engineer level 2 or 3 (19631*)
Northrop Grumman
Roy
Northrop Grumman Defense Systems is seeking a Systems Engineer / Principal Systems Engineer to join its team. This engineer will support the Sentinel program in Roy, UT. Northrop Grumman…
Added 1 day ago
Principal Production Systems Engineer Level 2/3 (AHT)
Northrop Grumman
Los Angeles
The ideal candidate will have experience in systems engineering lifecycle of missile / weapon system development program(s) and production experience. They will have technical knowledge in…

Lilly

Sr Principal Engineer - Data

Indianapolis, IN, United States

$129,000 - $211,200

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Job details

Pay: $129,000 - $211,200
Posting language: English
Posted: Sep 29, 2026

Original job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work - but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

We are seeking an experienced Senior Principal Data, Analytics & AI Engineer to join the Global DIA team within MQ Tech at Lilly. This role sits at the intersection of data engineering, supply chain domain expertise, and applied AI. You will architect the near-real-time data foundations that AI agents reason over and lead the design of the agents themselves - multi-agent workflows that read across manufacturing and supply chain systems, correlate signals that today sit in disconnected platforms, and put clear, actionable insight in front of the people running the line and the network.

This is a senior principal, hands-on delivery role with technical leadership expectations. You will own solutions end to end, set technical direction for correlating supply chain and manufacturing data through data modernization and agentic AI, and mentor engineers on the team. The solutions you build reach production and are used every shift, bringing transparency and decision support to Lilly's Supply Chain and Manufacturing operations.

Job Responsibilities

Technical leadership and architecture

Own the technical design and architecture for agentic AI and data modernization solutions across the Global Supply Chain and MQ landscape, from problem framing through production support.
Set standards and reusable patterns for cloud based data modeling, pipeline design, agent orchestration, and evaluation that other engineers build on.
Mentor and provide technical guidance to junior and mid-level engineers; lead code and design reviews.
Partner with senior business stakeholders and IT leadership to shape roadmaps, sequence delivery, and make build/buy trade-offs; direct and hold accountable external vendor and partner teams.

Supply chain data domain and analytics

Develop and apply deep working knowledge of Global Supply Chain data domains - material master, BOM and recipe, procurement, inventory and stock movements, production orders and batch execution, planning and scheduling, warehouse management, transportation management, distribution and logistics, quality and deviations.
Work fluently across SAP (S/4HANA, ECC, BW/4HANA - master data, MM, PP, QM, SD, and IBP) and SHARP , translating source-system semantics into trusted, business-ready data models.
Bring an informed point of view on end-to-end supply chain processes - S&OP, MRP, plan-to-produce, source-to-pay, order-to-cash, capacity and inventory management - and the analytics that support them, including service level, inventory turns, cycle time, schedule adherence, and supply risk.
Correlate supply chain and manufacturing data - linking ERP, planning, MES, historian, and quality data across systems and time - to produce integrated business solutions that answer questions no single system can, using data modernization and agentic AI.

Agentic AI and machine learning

Closely collaborate with the business & other global teams on agentic solution design, requirement gathering, solution development and delivery to drive meaningful business value
Design, build, and deploy AI agents and multi-agent workflows that automate analysis and decision support across manufacturing and supply chain use cases - including prompt engineering, tool and function calling, agent orchestration, and retrieval-augmented generation (RAG) over technical documents and operational data.
Define how agent performance is measured and improved: test scenarios, evaluation criteria, accuracy and hallucination monitoring, user feedback loops, agent observability, and guardrails that keep agent behavior safe, grounded, and within scope.
Implement, test, and deploy machine learning and predictive models into production, ensuring performance, scalability, and interpretability.

Data engineering and delivery

Design, build, and maintain scalable, reliable data pipelines using modern ETL/ELT tooling to ingest, process, and transform large datasets from diverse operational and enterprise sources in support of advanced analytics, reporting, and agentic AI.
Lead data modernization efforts - migrating and re-platforming legacy supply chain reporting and data assets onto modern lakehouse and cloud architectures.
Monitor and troubleshoot data quality and agent behavior issues, ensuring data integrity and reliability across all platforms.
Develop and maintain documentation for data architecture, data flows, agent designs, prompts, model choices, and deployments to support maintainability, validation, and GxP/CSV requirements.
Ensure compliance with all relevant data privacy, security, and responsible AI requirements.
Stay abreast of the fast-moving agentic AI and data engineering landscape and bring practical, proven advances into the team's work.

Basic Qualifications

Bachelor’s in Computer Science, Engineering, Data Science, Statistics, Supply Chain, or related field with 8+ years in data engineering, analytics, or AI/ML, with hands-on production Gen-AI/agentic app delivery.
Experience in supply chain/manufacturing data, hands-on SAP (S/4HANA/ECC, BW/4HANA) , SHARP, MES and related data and analytics experience.
Hands-on advanced statistical, machine learning, LLM/agentic app development: prompt engineering, tool/function calling, RAG, vector search/embeddings, multi-step workflows.
Deep knowledge of agent frameworks (LangChain, LangGraph, or equivalent) and production LLM APIs (OpenAI, Azure OpenAI, Anthropic, Bedrock); Azure/AWS/Databricks.
Advanced Python (preferred); SQL,Java/Scala/R a plus, PowerBi/Tablue, Web Apps etc
Experience in end-to-end developing production grade analytics systems.

Preferred Qualifications

Masters in Computer Science, Engineering, Data Science, Statistics, Supply Chain, or related field with 5+ years in data engineering, analytics, or AI/ML, with hands-on production Gen-AI/agentic app delivery.
Experience in pharmaceutical, life sciences, or other regulated manufacturing supply chains.
Track record of taking multiple AI or agentic solutions through to production, including evaluation, monitoring, and iteration after go-live.
Strong command of manufacturing processes and metrics (OEE, downtime, yield, batch performance, right-first-time) alongside supply chain metrics.
Experience with supply chain planning software (SAP IBP, Kinaxis, o9) and IoT/streaming operational data.
Exposure to manufacturing data sources such as historians (OSI PI), MES/TrakSYS, PMX, or LIMS.
Experience working in a GxP-regulated environment, including CSV and validation practices.
Experience with data visualization tools (Power BI preferred).
Applied knowledge of responsible AI practices: model risk, bias, explainability, and data privacy.
Experience leading globally distributed teams or vendor partners.
Databricks, AWS or Azure certifications.

Additional Information:

· Position is located in Indianapolis, Indiana

· Full time position 5 days per week onsite

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$129,000 - $211,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

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