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Added 13 mins ago
Engagement Manager
Cprime
Remote, United States
This is not simply a project coordinator role, nor is it expected to be the primary hands-on developer or solution architect. Successful Engagement Managers are comfortable operating…
Added 32 mins ago
Lead AI/ML Architect
ResMed SaaS Holdings Inc.
San Diego, CA
We are seeking a Machine Learning Product Architect to define, scale and guide the architectural vision for our AI, ML, and GenAI products. This is a senior, highly visible role that sits…
Added 2 hours ago
Partnerships Manager
Baselayer
NY
The Agentic Economy team is extending Baselayer's business graph into the trust layer for agentic commerce: verifiable credentials that bind an agent to the verified business and human…
Added 4 hours ago
TT
Senior/Staff Product Engineer, Applied AI
True Talent Solutions Partners
San Francisco, CA
- $200,000 to $300,000 USD / year
- Architect and lead core backend systems, including real-time matching and automated vetting pipelines.
Added 5 hours ago
Data Scientist
Social Security Administration
Woodlawn, MD
…visit the new resume guidance for more information. Duties: Architect, develop, and maintain advanced analytics solutions using Python, R, and SQL on enterprise data platforms. Design and…
Added 5 hours ago
Solutions Architect
Social Security Administration
Woodlawn, MD
Added 7 hours ago
Principal Generative AI Engineering Lead - Senior Vice President
Citigroup
Irving, TX
…visionary prinicipal Generative AI/AI Lead to guide our team and architect the next generation of intelligent systems. This is a pivotal role in driving our AI project execution, from…
Added 7 hours ago
Senior LLM Agents Architect
NVIDIA Corporation
North District, IL
We are looking for a senior LLM Agents Architect to work hands-on with hardware architects, verification engineers, GPU performance experts, and software developers to build end-to-end…
Added 7 hours ago
Senior System Security Architect
NVIDIA Corporation
South District, IL · North District, IL
…and engineering workflows. We are seeking a Senior Security Architect to design, build, and deploy intelligent AI agent systems tackling NVIDIA's most complex security challenges. Working…
Added 7 hours ago
Senior Hardware Architect Artificial Intelligence
NVIDIA Corporation
North District, IL
We strive to define and implement this new agentic hardware architecture, and we are seeking an experienced architecture lead for our AI-for-Architecture team within the Networking…
Added 7 hours ago
Senior Product Security Compliance Architect
NVIDIA Corporation
North District, IL
…seeking a proactive, highly technical Product Security Compliance Architect to join the NVIDIA Networking product security team. In this role, you will bridge the gap between deep system…
Added 7 hours ago
Senior AI Performance Network Architect
NVIDIA Corporation
North District, IL
…with artificial intelligence. We are seeking an AI Networking Architect to join the Networking Research Group. This role bridges the gap between emerging AI workloads and the data center…
Added 7 hours ago
Customer AI Solution Architect
Deloitte US
Atlanta, GA · Austin, TX · Baltimore, MD · Boston, MA · Charlotte, NC · Chicago, IL · Cincinnati, OH · Cleveland, OH · Columbus, OH · Dallas, TX · Denver, CO · Detroit, MI · Hartford, CT · Houston, TX · Indianapolis, IN · Jacksonville, FL · Kansas City, MO · Las Vegas, NV · Los Angeles, CA · McLean, VA · Miami, FL · Milwaukee, WI · Minneapolis, MN · Morristown, NJ · Nashville, TN · New Orleans, LA · NY · Philadelphia, PA · Pittsburgh, PA · Portland, OR · Raleigh, NC · Richmond, VA · Sacramento, CA · San Diego, CA · San Francisco, CA · San Jose, CA · Seattle, WA · St. Louis, MO · Stamford, CT · Tampa, FL · Tempe, AZ
Architect agentic customer experiences for marketing, commerce, sales, and service, including customer assistants, conversational commerce, personalization, sales enablement, and support…
Added 7 hours ago
Agentic AI Delivery Consultant
Deloitte US
Gilbert, AZ · Lake Mary, FL · Mechanicsburg, PA
…design and deliver generative artificial intelligence (AI) and agentic AI solutions that address complex mission and business needs for government and public-sector…
Added 7 hours ago
Converge for FSI - RAE Lead Product Forward Deployed Engineer_Products & Platforms
Deloitte US
Arlington Heights, IL · Atlanta, GA · Austin, TX · Baltimore, MD · Bellevue, WA · Birmingham, AL · Boise, ID · Boston, MA · Charlotte, NC · Chicago, IL · Cincinnati, OH · Cleveland, OH · Colorado Springs, CO · Columbus, OH · Costa Mesa, CA · Dallas, TX · Davenport, IA · Dayton, OH · Denver, CO · Des Moines, IA · Detroit, MI · Fort Worth, TX · Fresno, CA · Ft. Lauderdale, FL · Gilbert, AZ · Grand Rapids, MI · Hartford, CT · Hermitage, TN · Honolulu, HI · Houston, TX · Huntsville, AL · Indianapolis, IN · Inglewood, CA · Jacksonville, FL · Jericho, NY · Jersey City, NJ · Kansas City, MO · Lake Mary, FL · Lansing, MI · Las Vegas, NV · Los Angeles, CA · Louisville, KY · McLean, VA · Mechanicsburg, PA · Memphis, TN · Miami, FL · Midland, MI · Milwaukee, WI · Minneapolis, MN · Monterey, CA · Morristown, NJ · Nashville, TN · New Orleans, LA · NY · Omaha, NE · Philadelphia, PA · Pittsburgh, PA · Portland, OR · Princeton, NJ · Raleigh, NC · Richmond, VA · Rochester, NY · Rosslyn, VA · Sacramento, CA · Salt Lake City, UT · San Antonio, TX · San Diego, CA · San Francisco, CA · San Jose, CA · Seattle, WA · St. Louis, MO · Stamford, CT · Tallahassee, FL · Tampa, FL · Tempe, AZ · Tulsa, OK · Washington, DC · Westlake, TX · Wichita, KS · Williamsville, NY
…product-market fit. This role is focused on the Retirement Agentic Ecosystem (RAE), an AI-enabled platform that connects retirement systems and coordinates workflows across plan onboarding,…
Added 7 hours ago
Converge Signals, FSI - Engineering Lead_Products & Platforms
Deloitte US
Arlington Heights, IL · Atlanta, GA · Austin, TX · Baltimore, MD · Bellevue, WA · Birmingham, AL · Boise, ID · Boston, MA · Charlotte, NC · Chicago, IL · Cincinnati, OH · Cleveland, OH · Colorado Springs, CO · Columbus, OH · Costa Mesa, CA · Dallas, TX · Davenport, IA · Dayton, OH · Denver, CO · Des Moines, IA · Detroit, MI · Fort Worth, TX · Fresno, CA · Ft. Lauderdale, FL · Gilbert, AZ · Grand Rapids, MI · Hartford, CT · Hermitage, TN · Honolulu, HI · Houston, TX · Huntsville, AL · Indianapolis, IN · Inglewood, CA · Jacksonville, FL · Jericho, NY · Jersey City, NJ · Kansas City, MO · Lake Mary, FL · Lansing, MI · Las Vegas, NV · Los Angeles, CA · Louisville, KY · McLean, VA · Mechanicsburg, PA · Memphis, TN · Miami, FL · Midland, MI · Milwaukee, WI · Minneapolis, MN · Monterey, CA · Morristown, NJ · Nashville, TN · New Orleans, LA · NY · Omaha, NE · Philadelphia, PA · Pittsburgh, PA · Portland, OR · Princeton, NJ · Raleigh, NC · Richmond, VA · Rochester, NY · Rosslyn, VA · Sacramento, CA · Salt Lake City, UT · San Antonio, TX · San Diego, CA · San Francisco, CA · San Jose, CA · Seattle, WA · St. Louis, MO · Stamford, CT · Tallahassee, FL · Tampa, FL · Tempe, AZ · Tulsa, OK · Washington, DC · Westlake, TX · Wichita, KS · Williamsville, NY
Demonstrated ability to take a working prototype and re-architect it for production scale, cost, and reliability - not just incremental feature work
Added 7 hours ago
Ascend Engineering Foundation (AEF) - Cloud Architect_Products & Platforms
Deloitte US
Arlington Heights, IL · Atlanta, GA · Austin, TX · Baltimore, MD · Bellevue, WA · Birmingham, AL · Boise, ID · Boston, MA · Charlotte, NC · Chicago, IL · Cincinnati, OH · Cleveland, OH · Colorado Springs, CO · Columbus, OH · Costa Mesa, CA · Dallas, TX · Davenport, IA · Dayton, OH · Denver, CO · Des Moines, IA · Detroit, MI · Fort Worth, TX · Fresno, CA · Ft. Lauderdale, FL · Gilbert, AZ · Grand Rapids, MI · Hartford, CT · Hermitage, TN · Honolulu, HI · Houston, TX · Huntsville, AL · Indianapolis, IN · Inglewood, CA · Jacksonville, FL · Jericho, NY · Jersey City, NJ · Kansas City, MO · Lake Mary, FL · Lansing, MI · Las Vegas, NV · Los Angeles, CA · Louisville, KY · McLean, VA · Mechanicsburg, PA · Memphis, TN · Miami, FL · Midland, MI · Milwaukee, WI · Minneapolis, MN · Monterey, CA · Morristown, NJ · Nashville, TN · New Orleans, LA · NY · Omaha, NE · Philadelphia, PA · Pittsburgh, PA · Portland, OR · Princeton, NJ · Raleigh, NC · Richmond, VA · Rochester, NY · Rosslyn, VA · Sacramento, CA · Salt Lake City, UT · San Antonio, TX · San Diego, CA · San Francisco, CA · San Jose, CA · Seattle, WA · St. Louis, MO · Stamford, CT · Tallahassee, FL · Tampa, FL · Tempe, AZ · Tulsa, OK · Washington, DC · Westlake, TX · Wichita, KS · Williamsville, NY
…AEF brings together cloud infrastructure, integration, AI and agentic capabilities, access controls and AppStore deployment patterns to simplify application modernization and client…
Added 7 hours ago
Senior, Full Stack Engineer - Tax Transformation
Deloitte US
Atlanta, GA · Boston, MA · Charlotte, NC · Chicago, IL · Costa Mesa, CA · Dallas, TX · Denver, CO · Grand Rapids, MI · Hartford, CT · Lake Mary, FL · Los Angeles, CA · McLean, VA · NY · Philadelphia, PA · Pittsburgh, PA · Raleigh, NC · Rosslyn, VA · San Diego, CA · San Francisco, CA · Seattle, WA · Tampa, FL · Washington, DC
Prior experience developing agentic AI applications or GenAI-powered modules.
Added 8 hours ago
Apps Development Group Manager - Senior Vice President
Citigroup
Tampa, FL
…responsible for designing and engineering enterprise grade Agentic AI solutions capable of integrating data from multiple heterogeneous systems and operating reliably at…
Added 9 hours ago
Lead ML/AI Engineer
TailorCare
United States
Set technical direction and production standards for our production GenAI applications, including LLM pipelines and agentic workflows, with the evaluation, retrieval, guardrail, and cost…
Added 11 hours ago
VP, Compute
Crux AI
Palo Alto, CA
- Architect and deliver the full compute lifecycle: hardware onboarding and inventory, OS and firmware provisioning, burn-in and validation, rack certification, customer handoff, repair and…
Added 11 hours ago
Technology Consulting - TMT - Forward Deployed Engineer - Senior
EY
Atlanta, GA · Houston, TX · Dallas, TX · San Francisco, CA · San Jose, CA · Miami, FL · Chicago, IL · San Antonio, TX
Design, develop, test, deploy, and support production-grade generative AI, RAG, and agentic solutions.
Added 11 hours ago
Technology Consulting - TMT - Forward Deployed Engineer - Sr Manager
EY
Chicago, IL · Houston, TX · Miami, FL · New York, NY · San Antonio, TX · San Francisco, CA · Dallas, TX
Own end-to-end architecture for strategic generative AI, RAG, and agentic programs, including service boundaries, orchestration, data contracts, evaluation frameworks, and operational…
Added 12 hours ago
AI Business Partner Senior Principal
The Cigna Group
Bloomfield, CT
AI-native practice is expected at a leadership level - spec-driven development, agentic tooling, and the judgment to know when to engage hands-on versus when to orchestrate teams and forums.
Added 12 hours ago
Sr. Staff Software Engineer, Cribl Dete
CRIBL INC
MADISON, WI

Lilly

Sr Principal Engineer - Data

Indianapolis, IN, United States

$129,000 - $211,200

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Job details

Pay: $129,000 - $211,200
Posting language: English
Posted: Sep 29, 2026

Original job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work - but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

We are seeking an experienced Senior Principal Data, Analytics & AI Engineer to join the Global DIA team within MQ Tech at Lilly. This role sits at the intersection of data engineering, supply chain domain expertise, and applied AI. You will architect the near-real-time data foundations that AI agents reason over and lead the design of the agents themselves - multi-agent workflows that read across manufacturing and supply chain systems, correlate signals that today sit in disconnected platforms, and put clear, actionable insight in front of the people running the line and the network.

This is a senior principal, hands-on delivery role with technical leadership expectations. You will own solutions end to end, set technical direction for correlating supply chain and manufacturing data through data modernization and agentic AI, and mentor engineers on the team. The solutions you build reach production and are used every shift, bringing transparency and decision support to Lilly's Supply Chain and Manufacturing operations.

Job Responsibilities

Technical leadership and architecture

Own the technical design and architecture for agentic AI and data modernization solutions across the Global Supply Chain and MQ landscape, from problem framing through production support.
Set standards and reusable patterns for cloud based data modeling, pipeline design, agent orchestration, and evaluation that other engineers build on.
Mentor and provide technical guidance to junior and mid-level engineers; lead code and design reviews.
Partner with senior business stakeholders and IT leadership to shape roadmaps, sequence delivery, and make build/buy trade-offs; direct and hold accountable external vendor and partner teams.

Supply chain data domain and analytics

Develop and apply deep working knowledge of Global Supply Chain data domains - material master, BOM and recipe, procurement, inventory and stock movements, production orders and batch execution, planning and scheduling, warehouse management, transportation management, distribution and logistics, quality and deviations.
Work fluently across SAP (S/4HANA, ECC, BW/4HANA - master data, MM, PP, QM, SD, and IBP) and SHARP , translating source-system semantics into trusted, business-ready data models.
Bring an informed point of view on end-to-end supply chain processes - S&OP, MRP, plan-to-produce, source-to-pay, order-to-cash, capacity and inventory management - and the analytics that support them, including service level, inventory turns, cycle time, schedule adherence, and supply risk.
Correlate supply chain and manufacturing data - linking ERP, planning, MES, historian, and quality data across systems and time - to produce integrated business solutions that answer questions no single system can, using data modernization and agentic AI.

Agentic AI and machine learning

Closely collaborate with the business & other global teams on agentic solution design, requirement gathering, solution development and delivery to drive meaningful business value
Design, build, and deploy AI agents and multi-agent workflows that automate analysis and decision support across manufacturing and supply chain use cases - including prompt engineering, tool and function calling, agent orchestration, and retrieval-augmented generation (RAG) over technical documents and operational data.
Define how agent performance is measured and improved: test scenarios, evaluation criteria, accuracy and hallucination monitoring, user feedback loops, agent observability, and guardrails that keep agent behavior safe, grounded, and within scope.
Implement, test, and deploy machine learning and predictive models into production, ensuring performance, scalability, and interpretability.

Data engineering and delivery

Design, build, and maintain scalable, reliable data pipelines using modern ETL/ELT tooling to ingest, process, and transform large datasets from diverse operational and enterprise sources in support of advanced analytics, reporting, and agentic AI.
Lead data modernization efforts - migrating and re-platforming legacy supply chain reporting and data assets onto modern lakehouse and cloud architectures.
Monitor and troubleshoot data quality and agent behavior issues, ensuring data integrity and reliability across all platforms.
Develop and maintain documentation for data architecture, data flows, agent designs, prompts, model choices, and deployments to support maintainability, validation, and GxP/CSV requirements.
Ensure compliance with all relevant data privacy, security, and responsible AI requirements.
Stay abreast of the fast-moving agentic AI and data engineering landscape and bring practical, proven advances into the team's work.

Basic Qualifications

Bachelor’s in Computer Science, Engineering, Data Science, Statistics, Supply Chain, or related field with 8+ years in data engineering, analytics, or AI/ML, with hands-on production Gen-AI/agentic app delivery.
Experience in supply chain/manufacturing data, hands-on SAP (S/4HANA/ECC, BW/4HANA) , SHARP, MES and related data and analytics experience.
Hands-on advanced statistical, machine learning, LLM/agentic app development: prompt engineering, tool/function calling, RAG, vector search/embeddings, multi-step workflows.
Deep knowledge of agent frameworks (LangChain, LangGraph, or equivalent) and production LLM APIs (OpenAI, Azure OpenAI, Anthropic, Bedrock); Azure/AWS/Databricks.
Advanced Python (preferred); SQL,Java/Scala/R a plus, PowerBi/Tablue, Web Apps etc
Experience in end-to-end developing production grade analytics systems.

Preferred Qualifications

Masters in Computer Science, Engineering, Data Science, Statistics, Supply Chain, or related field with 5+ years in data engineering, analytics, or AI/ML, with hands-on production Gen-AI/agentic app delivery.
Experience in pharmaceutical, life sciences, or other regulated manufacturing supply chains.
Track record of taking multiple AI or agentic solutions through to production, including evaluation, monitoring, and iteration after go-live.
Strong command of manufacturing processes and metrics (OEE, downtime, yield, batch performance, right-first-time) alongside supply chain metrics.
Experience with supply chain planning software (SAP IBP, Kinaxis, o9) and IoT/streaming operational data.
Exposure to manufacturing data sources such as historians (OSI PI), MES/TrakSYS, PMX, or LIMS.
Experience working in a GxP-regulated environment, including CSV and validation practices.
Experience with data visualization tools (Power BI preferred).
Applied knowledge of responsible AI practices: model risk, bias, explainability, and data privacy.
Experience leading globally distributed teams or vendor partners.
Databricks, AWS or Azure certifications.

Additional Information:

· Position is located in Indianapolis, Indiana

· Full time position 5 days per week onsite

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$129,000 - $211,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

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