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Lilly

HSE by Design Engineer

Indianapolis, IN, United States

$129,000 - $211,200

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Job details

Pay: $129,000 - $211,200
Posting language: English
Posted: Nov 10, 2026

Original job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work - but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Advisor – HSE Design & Process Safety, GFD

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Global Facilities Delivery (GFD) Organization, part of Manufacturing & Quality, delivers new and renovated capital assets around the world. Our mission is accomplished through a highly leveraged organization of design, construction, and qualification contractors. Many of the assets delivered focus on medical innovation and delivering innovative solutions to patients. Some of the assets delivered will expand the supply of existing medicines or strengthen the supply chain.

The Advisor – HSE Design & Process Safety ensures HSE requirements are designed into GFD capital projects at every stage, in line with company policies, procedures, and applicable regulations. This senior individual contributor evaluates HSE impacts across the full project lifecycle, from feasibility and front-end planning through detailed design, construction, commissioning, start-up, and turnover to operations. The role serves as the HSE project lead and functional safety subject matter expert on assigned projects, working closely with Process Engineering, Operations, Maintenance, and Process Control teams and driving clean handoffs between project phases, GFD, site operations, and the HSE function.

Key Objectives/Deliverables

HSE by Design & Front-End Planning: Lead HSE-by-design reviews through design and start-up for major capital projects. Provide technical input to Requests for Capital Expenditure (RCE) so significant safety and environmental aspects are built into front-end planning for new product introductions, product transfers, and changes to existing processes and equipment. Lead hazard screening for tech transfers and new product introductions, and partner with project, facilities, engineering, and contractor teams to integrate HSE requirements into execution plans.
Process Safety & Risk Assessment: Lead Hazard and Operability Studies (HAZOP) and conduct ATEX risk assessments and prepare Explosion Protection Documents. Identify hazards in process design and operations, document findings, and recommend controls to minimize or eliminate risk. Ensure HSE design rationale is complete and that site teams understand their safety systems and how they operate.
Functional Safety & Safety Instrumented Systems: Lead or support the design of new Safety Instrumented Systems (SIS) and modifications to existing systems. Support lifecycle management, performance, and compliance of SIS, Distributed Control Systems (DCS), and associated applications on assigned projects.
Construction, Commissioning & Start-Up: Support HSE planning for site setup, construction, installation, commissioning, and start-up. Lead Pre-Startup Safety Reviews (PSSR) to confirm safety requirements are met before start-up, maintain life safety compliance and continuity from construction through full production, and support completeness of all declarations of conformity for active and completed projects.
Management of Change & HSE Culture: Manage the Management of Change (MOC) process on assigned projects so that changes to processes and operations meet safety requirements. Contribute to GFD’s framework for HSE project health checks and health index reporting, and foster a strong HSE culture as projects transition into full production.

Minimum Requirements

Bachelor’s degree in chemical, environmental, or mechanical engineering, or a related field.
Minimum of ten (10) years of experience in HSE, process safety, or engineering roles supporting capital projects in a manufacturing or industrial environment, including hazard analysis (e.g., HAZOP, ATEX) and safety review processes (e.g., PSSR, MOC) in a regulated industry.
Willingness to travel to support projects across the global site network.

Additional Preferences

Certified Functional Safety Expert (CFSE) or equivalent functional safety credential.
Professional Engineer (PE) license or equivalent.
Strong working knowledge of process safety management, functional safety, and applicable HSE regulations.
Demonstrated ability to lead cross-functional teams through design reviews, hazard assessments, and safety approvals on project timelines.
Excellent written and verbal communication skills, including the ability to translate technical safety requirements for non-HSE stakeholders.

Additional Information

· This is a senior individual contributor role with no direct reports.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$129,000 - $211,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

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More about this job

Skills

Supply chain management
Process engineering
Hazard assessment
Design process
SIS
Regulatory compliance
Control systems
DCS
Reporting
Mechanical engineering
P.Eng.
Communication skills
Leadership

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Work requirements

Jobs in the United States