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Added 5 mins ago
IPS Analysis Chief (Associate Project Manager 2)
City of New York
Queens, NY
Within DEP’s Bureau of Water and Sewer Operations, the Division of Operations Analysis and Regulatory Compliance contains the IPS Analysis Unit (the Unit). The Unit is seeking to hire an…
Added 5 mins ago
Deputy Director, Data Analytics
City of New York
New York City, NY
…technical execution with decision support translating complex data into plain-language business intelligence, managing tight deadlines, and maintaining rigorous accuracy to inform strategic…
Added 5 mins ago
Operations Coordinator
City of New York
New York City, NY
…Technology (BOLT) has an exciting opportunity to work as an Operations…
Added 6 mins ago
Engineer-In-Charge
City of New York
New York City, NY
Only candidates who are permanent in the Associate Project Manager title, or those who are reachable on DDC’s promotional list for exam #3573 or the open-competitive list for exam #3110 may…
Added 6 mins ago
STAFF ANALYST, LEVEL 2 - FAMILY COURT
City of New York
New York, NY
Using the Law Department case management system, Excel, Word, PowerPoint, ARC GIS, and other systems, the Staff Analyst will monitor all data for accuracy.
Added 6 mins ago
Media Services Technician
City of New York
New York City, NY
KCDA is seeking a versatile and motivated Multimedia Services Technician to join the Multimedia Division. Multimedia operations include multiple functional areas, including courtroom…
Added 6 mins ago
DEPUTY DIRECTOR, HR RECORDS MANAGEMENT/ADMINISTRATIVE SERVICE
City of New York
New York, NY
APPLICANTS MUST BE PERMANENT IN THE PRINCIPAL ADMINISTRATIVE ASSOCIATE CIVIL SERVICE
Added 20 mins ago
Electrical Facilities Maintenance Engineer (Electrical Engineer V)
State of Massachusetts
185 Kneeland Street, MA
…the Electrical Facilities Maintenance Engineer supports the operations of electrical lighting and control systems for tunnels, facilities, and roadways. * This includes, but is not limited…
Added 20 mins ago
Administrative Assistant II - STEM
State of Massachusetts
Middleton, MA
Added 20 mins ago
V
ACCOUNTS PAYABLE SPECIALIST
VulcanForms
Ayer, MA
- $61,396 to $84,419 USD / year
…manufacturing, precision machining, software, automation, and operations expertise, we deliver end-to-end production at scale. About the Role: Support the day-to-day financial operations of…
Added 20 mins ago
Accounts Payable Specialist
VulcanForms
Ayer, MA
The Accounts Payable Specialist plays a critical role in supporting the day-to-day financial operations of the organization by ensuring timely, accurate, and efficient processing of vendor…
Added 20 mins ago
Assistant District Bridge Engineer/Design & Review (Civil Engineer V)
State of Massachusetts
Taunton, MA
…projects; prepare and/or review reports, studies and analytical data; perform calculations relating to engineering problems; perform engineering surveys; inspect construction and/or…
Added 20 mins ago
Assistant District Construction Engineer/Design-Build (Civil Engineer V)
State of Massachusetts
Taunton, MA
…projects; prepare and/or review reports, studies and analytical data: perform calculations relating to engineering problems: perform engineering surveys: inspect construction and or…
Added 20 mins ago
IT Supervisor
EMCOR Group
Norwood, MA
…construction methods that help improve efficiency and enhance client…
Added 21 mins ago
Associate Scientist - Downstream Process Development
Lilly
Boston, MA
…chromatography (AEX/CEX), membrane chromatography, and polishing…
Added 21 mins ago
Associate, Portfolio Company Management
Manulife
Boston, MA
The Associate, Portfolio Company Management supports the Farmland Plus strategy by working closely with the Senior Director of Portfolio Company Management and portfolio company leadership…
Added 36 mins ago
MG
Program Coordinator
Massachusetts General Hospital
Charlestown, MA
- $22.22 to $31.71 USD / hour
…enhance program effectiveness. Contributes to reporting and data analysis to assess program impact and support strategic improvements. Provides guidance and support to other team…
Added 36 mins ago
Plant Smart Factory Lead
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Lead the design, development, and implementation of software and automation solutions to enhance data analytics capabilities and overall plant performance.
Added 36 mins ago
Associate Business Technology Analyst
Dominion Energy
CAYCE, SC
The Associate Business Technology Analyst supports AI-related research, evaluation, and solution delivery activities within the AI and Emerging Technologies team. Working under appropriate…
Added 36 mins ago
UAS Technical Analyst
CACI International
SC
BA/BS and 6 years of experience, associate’s degree plus 9 years of experience or 11 years of recent specialized experience.
Added 36 mins ago
EC
Associate Production Supervisor
Eaton Corporation
Sumter, SC
- $71,000 to $105,000 USD / year
The Associate Production Supervisor supports frontline manufacturing operations within an assigned production area to achieve safety, quality, delivery, inventory, and productivity…
Added 37 mins ago
Admin. Associate II, Brokerage Operations & Trade Compliance M-F 8am - 4:30PM (Local Remote)
UPS
AIKEN, SC
…general customs brokerage activities and general office and data entry…
Added 37 mins ago
Contract Compliance Specialist
Federal Law Enforcement Training Centers
North Charleston, SC
…and mission. This position is located in the Office of the Associate Director for Training Ops, Training Management Operations Directorate, Office of Charleston Operations, Charleston…
Added 38 mins ago
Transaction Specialist
City of New York
New York City, NY
…government and is instrumental to the successful day-to-day operations of the City of New…
Added 38 mins ago
CLERICAL ASSOCIATE L04
City of New York
Bronx, NY
1. Create, track and maintain comprehensive reports; analyze and prepare reports for Operations' employees; perform data research.

Lilly

Associate Scientist - Downstream Process Development

Boston, MA, United States

$72,000 - $189,200

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Job details

Pay: $72,000 - $189,200
Experience: 5+ years(master’s/PhD) with 3+ years, of relevant downstream process development experience in industry
Posting language: English
Posted: Nov 6, 2026

Original job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work - but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

We are seeking a highly motivated Scientist to join the Downstream Process Development team. The successful candidate will lead development and optimization of downstream purification processes supporting viral vector programs from research through preclinical development.

The ideal candidate will possess deep technical expertise in downstream purification technologies including ultracentrifugation, chromatography, and tangential flow filtration (TFF), with demonstrated experience driving process development strategies, platform development initiatives, technology implementation, and multi-functional collaboration.

This role requires strong scientific leadership, hands-on technical capability, and the ability to independently lead complex purification development activities in a fast-paced environment.

Key Responsibilities

Lead development, optimization, and scale-up of downstream purification workflows for viral vectors.
Design and implement purification strategieusingng Iodixanol and CsCl density gradient ultracentrifugation, affinity chromatography, ion-exchange chromatography (AEX/CEX), membrane chromatography, and polishing operations.
Lead AKTA-based chromatography workflow development and process intensification initiatives.
Develop scalable downstream platform approaches to support rapid material generation and process consistency across programs.
Independently design experiments, analyze data, interpret results, and present technical conclusions to multi-functional teams and leadership.
Drive troubleshooting, process characterization, and process robustness studies.
Collaborate closely with upstream, analytical, manufacturing, and external partners to support program work and timelines.
Support technology transfer, process documentation, and development reports.
Lead development and optimization of TFF/UFDF workflows for concentration, buffer exchange, formulation, and process scalability.
Mentor junior scientists/engineers and provide technical guidance across purification activities.
Contribute to implementation of new purification technologies, automation tools, and continuous process improvements.
Ensure compliance with safety, documentation, and quality standards.

Basic Qualifications

Bachelor’s degree in biology, biochemistry, chemical engineering, biotechnology, or related scientific field
5+ years(master’s/PhD) with 3+ years, of relevant downstream process development experience in industry

Additional Skills/Preferences:

CsCl and iodixanol ultracentrifugation
Affinity chromatography
Ion-exchange chromatography
TFF/UFDF operations including concentration, diafiltration, and formulation development
AKTA systems and Unicorn software
Strong understanding of process scale-up, platform development, and purification process characterization.
Experience analyzing purification performance and product quality attributes using relevant analytical methods.
Experience in AAV downstream process development and capsid enrichment workflows.
Experience with automated chromatography systems and process intensification strategies.
Experience supporting technology transfer and manufacturing readiness activities.
Familiarity with GMP development environments and regulatory expectations.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$72,000 - $189,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

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Skills

Research
Workflow
Leadership
Troubleshooting
Documentation
Regulatory compliance
Chemical engineering
Biotechnology
Good manufacturing practices

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