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Added 2 mins ago
FLIGHT DECK Capability Building Partner
GE Aerospace
Saint Louis, MO
+ Proven cross-functional project leadership and program management across multiple initiatives, timelines, and stakeholders, including the ability to set strategy, establish standard work,…
Added 2 mins ago
FLIGHT DECK Capability Building Partner
GE Aerospace
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+ Proven cross-functional project leadership and program management across multiple initiatives, timelines, and stakeholders, including the ability to set strategy, establish standard work,…
Added 3 mins ago
IT Project Manager
Stafford Gray
Remote, United States
Must live within reasonable commuting distance of Lansing, MI
Added 4 mins ago
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Assistant General Counsel, Commercial
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Denver, CO
- $180,000 to $216,000 USD / year
You will provide professional legal advice, counsel, and guidance to support the development, construction, finance and management of Invenergy's growing renewable and clean energy…
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Manager, Origination
Invenergy LLC
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- $140,000 to $165,000 USD / year
…and operate large scale projects that power communities and support the energy…
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Senior GIS Developer
Invenergy LLC
Denver, CO
- $90,000 to $115,000 USD / year
Use DevOps for version control and project management
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Project staffing, budget and schedule management.
Added 18 mins ago
Lead Discipline Field Engineer - CSA DMD
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Support the development of the construction engineering organization for approval by the Site Manager (or appropriate level of Project Management) and preparation of employee requisitions.
Added 19 mins ago
Lead Program Manager, Space Electronics
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At least 10 years of relevant program or project management experience.
Added 22 mins ago
Global EHS Leader, Colibrium Additive (m/f/d)
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GE Aerospace offers comprehensive benefits and programs to support your health and, along with programs like HealthAhead, your physical,emotional, financial and social wellbeing. Healthcare…
Added 29 mins ago
Project Coordinator - WMG
Wellstar Medical Group, LLC
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The Project Coordinator provides coordination for projects under the purview of a WMG department. This role is responsible for collaborating with leaders and project stakeholders to oversee…
Added 30 mins ago
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Director Facilities BHN
Bassett Healthcare Network
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- $152,901 USD / year
Minimum 5 years of previous leadership, management or supervisor experience required · Must possess a valid NYS Class D Drivers License and mainta
Added 33 mins ago
Integrated Study Timeline Manager
ICR United States USA
Remote, United States
…team members and stakeholders to develop, monitor, and adjust project timelines as needed. You will identify key study activities to drive study timeline development with minimal guidance…
Added 34 mins ago
Project Manager
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This position is responsible for successfully engaging with the client and managing project deliverables, including the scope of work as defined by the contract, as well as all support…
Added 43 mins ago
Senior Project Analyst - Software Development
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Senior Project Analyst – Software Development: Join a mission-focused team at the Defense Logistics Agency (DLA) dedicated to maintaining and modernizing critical medical logistics…
Added 43 mins ago
Global Fielding Services-Training Specialist
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Provide on-site field support during Army experimentation and exercise events, including Project Convergence Capstone, Warfighter Exercises, Combat Training Center (CTC) rotations, and…
Added 43 mins ago
Global Fielding Services-Training Specialist
GD Information Technology, Inc.
United States
Provide on-site field support during Army experimentation and exercise events, including Project Convergence Capstone, Warfighter Exercises, Combat Training Center (CTC) rotations, and…
Added 43 mins ago
Global Fielding Services-Training Specialist
GD Information Technology, Inc.
United States
Provide on-site field support during Army experimentation and exercise events, including Project Convergence Capstone, Warfighter Exercises, Combat Training Center (CTC) rotations, and…
Added 43 mins ago
Global Fielding Services-Training Specialist
GD Information Technology, Inc.
United States
Provide on-site field support during Army experimentation and exercise events, including Project Convergence Capstone, Warfighter Exercises, Combat Training Center (CTC) rotations, and…
Added 45 mins ago
Software Engineer II- Full-stack Developer
Deloitte
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+ Design, build, test, and maintain scalable full-stack features across front-end and back-end systems, following project engineering standards and conventions.
Added 46 mins ago
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Program Manager II
ManpowerGroup
Omaha, NE
- $68 to $71 USD / hour
Understanding of Agile and Waterfall approaches to support program execution across different project needs.
Added 46 mins ago
Software Engineer II- Full-stack Developer
Deloitte
Kansas City, MO
+ Design, build, test, and maintain scalable full-stack features across front-end and back-end systems, following project engineering standards and conventions.
Added 46 mins ago
Senior Software Engineer
STERIS Corporation
Minneapolis, MN
Contributes to cross functional project planning, development, and analysis of product requirements, and proposed solutions.
Added 55 mins ago
Senior Data Science Consultant, Cards and Personal Loans Decision Sciences
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Working as part of a project team the consultant will complete defined analytical and modeling-support assignments, translate established business needs into technical tasks, evaluate…
Added 56 mins ago
Clinical Program Senior Advisor - Remote - Express Scripts (Academic Detailing)
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Current pharmacist license required; relevant PBM, managed care, health plan, provider engagement, or clinical program experience preferred

Larimar Therapeutics

Associate Director, Analytical Science and Technology

PA, United States

Apply on recruiting.paylocity.com About employer

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Job details

Posting language: English
Posted: Nov 9, 2026

Original job description

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Description

The Company Larimar Therapeutics Inc. (Larimar) is a publicly held clinical-stage biotechnology company focused on developing treatments for patients suffering from complex rare diseases using its novel cell penetrating peptide technology platform. Our lead product candidate, Nomlabofusp (formerly referred to as CTI-1601), is a subcutaneously administered, recombinant fusion protein intended to deliver human frataxin (FXN), an essential protein to the mitochondria of patients with Friedreich’s ataxia. Friedreich’s ataxia is a rare, progressive, and fatal disease in which patients are unable to produce sufficient FXN due to genetic abnormality. The company has assembled an experienced management team, each of whom has over 20 years of pharmaceutical industry experience and has over 50 employees. Their management team, employees, and consultants have significant expertise in discovery, nonclinical and clinical development, regulatory affairs, and the development of manufacturing processes utilizing good manufacturing practices. The company’s strategy is to become a leader in the treatment of rare diseases by leveraging their technology platform and applying their team’s know-how to the development of nomlabofusp and other future pipeline projects. We are best characterized by entrepreneurial and scientific leadership and a participatory workforce committed to success. If you are searching for a company where urgency, agility, and commitment to science win the day – we welcome you![

Position Summary Larimar Therapeutics is seeking an experienced and highly motivated Analytical Scientist to provide scientific and strategic leadership for analytical development activities supporting a late-stage protein therapeutic. Reporting directly to the Head of Analytical Science and Technology, this individual will be responsible for establishing and executing analytical strategies and overseeing analytical method transfer, validation, and lifecycle management activities at external development and contract manufacturing organizations (CDMOs). The successful candidate will serve as a key technical leader across Drug Substance (DS) and Drug Product (DP) development, providing scientific oversight for analytical method development, qualification, validation, transfer, and ongoing method performance monitoring. This role will work closely with Process Development, Manufacturing, Quality, Regulatory Affairs, and external partners to ensure robust analytical support throughout product development and commercialization. The ideal candidate possesses deep expertise in protein therapeutic characterization and analytical control strategies, including hands-on experience with chromatographic, electrophoretic, and mass spectrometry-based analytical techniques used to support process development, release testing, comparability assessments, and stability programs. This individual will have a demonstrated track record of leading analytical activities for protein therapeutic programs from development through clinical manufacturing, with experience supporting regulatory submissions and health authority interactions. Experience serving in a CMC leadership role, such as Program Team Leader or CMC program Lead, is highly desirable.

Job Duties and Responsibilities

Analytical Development Leadership

Develop and execute analytical strategies to support the development, manufacture, characterization, and commercialization of protein therapeutics.
Provide scientific leadership and technical oversight for analytical method development, optimization, qualification, validation, transfer, and lifecycle management conducted internally and at contract laboratories.
Establish phase-appropriate analytical control strategies aligned with ICH guidelines, regulatory expectations, and product-specific risk assessments.
Lead analytical characterization programs, comparability assessments, forced degradation studies, stability studies, and product specification development activities.
Review and approve analytical methods, validation packages, technical reports, and supporting documentation ensuring compliance with cGMP and regulatory expectations.
Author and review SOPs and internal guidance documents to streamline business processes.
Drive scientific investigations related to analytical method performance, product quality attributes, and process-related changes.
Lead comparability assessments and critical quality attribute (CQA) evaluations to ensure process changes are appropriately assessed and maintained within established quality parameters.
Evaluate emerging analytical technologies and recommend approaches to strengthen product characterization and control strategies.

CMC and Program Leadership

Serve as the analytical sciences representative on cross-functional program and CMC teams.
Provide strategic input to process development, manufacturing, technology transfer, and product lifecycle management activities.
Lead or contribute to technical risk assessments and resolution of complex product, analytical, and process development challenges.
Provide oversight of analytical activities executed at CDMOs, contract laboratories, and external development partners.
Author, review, and approve technical documents, protocols, reports, regulatory filings, and responses to health authority inquiries.
Support regulatory submissions, agency interactions, inspections, and audit readiness activities.
Effectively communicate analytical development strategies, risks, and recommendations to internal stakeholders and senior management.

Requirements

Education and Experience

Bachelor’s degree in a relevant discipline and 15+ years of relevant professional experience; or
Master’s degree and 12+ years of relevant professional experience; or
Ph.D. and 8+ years of relevant professional experience.
Demonstrated experience leading analytical development activities supporting protein therapeutics in a biotechnology or pharmaceutical environment.
Experience supporting IND, BLA, MAA, or other global regulatory submissions.
Proven experience working with recombinant proteins, enzymes, fusion proteins, antibody fragments, or other protein-based therapeutics.
Experience managing analytical development, method transfer, and technology transfer activities at CDMOs and other external development partners.
Strong understanding of GxP regulations, quality systems, and pharmaceutical development principles.
Excellent leadership, communication, project management, and stakeholder management skills.
Ability to operate effectively in a fast-paced and evolving environment.
Demonstrated commitment to scientific excellence, continuous improvement, and collaborative problem-solving.

Technical Qualifications Candidates should possess hands-on experience developing, troubleshooting and qualifying, analytical methods commonly used for protein therapeutic development, including:

Size Exclusion Chromatography (SEC)
Reduced Capillary Electrophoresis Sodium Dodecyl Sulfate (rCE-SDS)
Non-Reduced Capillary Electrophoresis Sodium Dodecyl Sulfate (nrCE-SDS)
Reversed-Phase High-Performance Liquid Chromatography (RP-HPLC)
Ion Exchange Chromatography (IEX), including charge variant characterization
Peptide Mapping using LC-MS and/or UV detection

Strong understanding of protein structure-function relationships and advanced characterization techniques, including:

Analytical Ultracentrifugation (AUC)
Circular Dichroism (CD)
Differential Scanning Calorimetry (DSC)
Fourier Transform Infrared Spectroscopy (FTIR)
Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS)
Intact mass and peptide-level mass spectrometry characterization
Aggregation, fragmentation, oxidation, deamidation, glycation, and other protein degradation pathways

Benefits

Larimar Therapeutics offers all employees incentive stock options, a comprehensive benefits plan including 401K, and a flexible PTO policy.

We are committed to equal-employment principles, and we recognize the value of committed employees who feel they are being treated in an equitable and professional manner. We strive to find ways to attract, develop and retain the talent needed to meet business objectives, and to recruit and employ highly qualified individuals representing the diverse communities in which we live.

Employment policies and decisions on employment and promotion are based on merit, qualifications, performance, and business needs. The decisions and criteria governing the relationship with all candidates and employees are made in a non-discriminatory manner - without regard to age, race, color, national origin, gender (including pregnancy, childbirth or medical condition related to pregnancy or childbirth), gender identity or expression, religion, physical or mental disability, medical condition, legally protected genetic information, marital status, veteran status, military status, sexual orientation, or any other factor determined to be an unlawful basis for such decisions by federal, state, or local statutes.

Apply on recruiting.paylocity.com About employer

More about this job

Skills

Pharmaceutical industry
Regulatory affairs
Good manufacturing practices
Leadership
DP
Mass spectrometry
Documentation
Regulatory compliance
Business processes
Inspection
Biotechnology
Quality control systems
Communication skills
Project management
Stakeholder management
Process improvement
Problem solving
Troubleshooting

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Work requirements

Jobs in the United States