Jobs in the United States

25+ jobs

Group jobs by employerEmail me new jobs Save this search

Added 1 min ago
A
Sr Program Manager
Aerospace
Torrance, CA · Tempe, AZ · Phoenix, AZ
- $219,000 to $274,000 USD / year
YOU MUST HAVE
Added 6 mins ago
Associate Executive Projects
Rotech Healthcare Inc.
Orlando, FL
Track project milestones, action items, deadlines, deliverables, and reporting requirements.
Added 11 mins ago
AC
Senior Supply Chain Specialist
Aston Carter
Glendora, CA
- $35 to $70 USD / hour
Oversee end-to-end supply chain activities for multiple product lines, from procurement of materials through finished goods inventory management.
Added 11 mins ago
Water Quality Planner/Project Manager III (Senior Data Steward)
King County
Seattle, WA
The section’s Data Steward will work closely with program staff, information technology teams, analysts, records professionals, and section leadership. The successful candidate will have…
Added 11 mins ago
Real Estate Assistant Retail Asset Manager Assistant Vice President
Citigroup
CA
Citi is looking for a Real Estate Assistant Retail Asset Manager to join the West Retail Asset Management team, reporting to the West Senior Asset Manager. In this role, you will support…
Added 12 mins ago
A
Physical Security Design Manager / Project Manager
Actalent
Newport Beach, CA
- $110,000 to $154,000 USD / year
EXANTE360 is seeking a Physical Security Project Manager to support its growing mission-critical practice and manage complex physical-security consulting projects from kickoff through…
Added 12 mins ago
Senior/Principal Cybersecurity - Systems Security Engineering, Onsite
Sandia National Laboratories
Livermore, CA
…you like to contribute to the development of Sandia's risk management framework for digital systems? Are you up for the challenge to help enact a new vision for implementing digital systems…
Added 12 mins ago
Executive Director, Workplace Delivery
Genentech
South San Francisco, CA
15+ years of progressively responsible experience, including 5+ years at the project/program management level, and 10+ years at the senior leadership/executive level.
Added 12 mins ago
A
Sr Associate
Actalent
Thousand Oaks, CA
- $27 USD / hour
Ability to identify and elevate relevant technical or operational issues to project leads and line management in a timely manner.
Added 12 mins ago
Program Manager III
General Atomics
Poway, CA
This position typically reports to a senior program manager and is responsible for the planning, managing and technical performance of one or more developed or mature engineering program(s)…
Added 12 mins ago
DSP Algorithms Engineer (Lead or Senior)
The Boeing Company
El Segundo, CA
Project assignments typically span the unit life cycle, from internal trades, concept studies and system definition, to satellite unit development and test. Candidates will belong to or…
Added 12 mins ago
Senior Project Management Specialist, Cost Account Management Integrated Product Team Lead
The Boeing Company
El Segundo, CA
Boeing Defense, Space and Security (BDS) has an exciting opportunity for a Senior Project Management Specialist, Cost Account Management (CAM) Integrated Product Team (IPT) Lead (Level 5)…
Added 12 mins ago
Senior Integrated Product Team Lead, Space Electronics Programs
The Boeing Company
El Segundo, CA
Candidates must live in the immediate area or relocate at their own expense
Added 13 mins ago
DSP Comm Engineer (Associate or Mid-level)
The Boeing Company
El Segundo, CA
Project assignments typically span the unit life cycle, from internal trades, concept studies and system definition, to satellite unit development and test. Candidates will belong to a…
Added 13 mins ago
SSC/S6 CIO Project Leader
The MITRE Corporation
El Segundo, CA
The N113 Space Battle Management department fields capabilities and establishes cross cutting enablers to deliver an integrated resilient Space C2 and Sensing Enterprise for the Space…
Added 13 mins ago
Systems Engineer - Digital Signal Processing (Associate or Mid-level)
The Boeing Company
El Segundo, CA
…and international customers on the latest satellite systems. Project assignments typically span the unit life cycle, from internal trades, concept studies and system definition, to…
Added 13 mins ago
Customer Program Manager
Insight Global
Irvine, CA
Our Client is seeking a Senior Customer Program Manager. This role is responsible for driving successful execution of complex customer programs across the data center business. This role…
Added 13 mins ago
Senior Program Manager, Enterprise Data Governance
Google
Sunnyvale, CA
8 years of experience in program or project management.
Added 13 mins ago
Senior Technical Program Manager, Silicon Engineering
Google
Sunnyvale, CA
Share Senior Technical Program Manager, Silicon Engineering
Added 13 mins ago
EHS Specialist III (EHS Lead)
ThermoFisher Scientific
Sunnyvale, CA
Join our EHS team at Thermo Fisher Scientific and make a meaningful impact protecting people and the environment. As a Senior EHS Specialist, you'll provide strategic guidance and support…
Added 13 mins ago
Integrated Program Planner Level 1
Lockheed Martin
Sunnyvale, CA
…you will interface with Engineering, Business Operations, and Program Management and will brief senior management. Additionally, you will be responsible for developing a compliant…
Added 13 mins ago
Nurse Director, Hospital - Nursing Practice Professional Development
Kaiser Permanente
Santa Clara, CA
…short- and long-term operational initiatives and directing program, services, and/or systems development; aligning cross-functional programs including workplace and patient safety, human…
Added 13 mins ago
Manager, Physical Security Systems Operator - EPIC and Lab Security
Applied Materials
Santa Clara, CA
California-wide Security Operations Project Management
Added 13 mins ago
Manager of Platform DevOps
Zoom
San Jose, CA
…nuanced concepts to diverse audiences (e.g. both engineers and senior management). You can balance technical tradeoffs, and can adapt plans to deliver quickly on the most important goals…
Added 13 mins ago
Senior Program Manager
HNTB
San Jose, CA
20 years heavy civil transportation experience with a combination of a) proven program mgmt. and/or senior PMC role, b) managing or leading a team in successful delivery of PMC projects, c)…

Larimar Therapeutics

Associate Director, Analytical Science and Technology

PA, United States

Apply on recruiting.paylocity.com About employer

Applications open in a new tab.

Job details

Posting language: English
Posted: Nov 9, 2026

Original job description

Apply

Description

The Company Larimar Therapeutics Inc. (Larimar) is a publicly held clinical-stage biotechnology company focused on developing treatments for patients suffering from complex rare diseases using its novel cell penetrating peptide technology platform. Our lead product candidate, Nomlabofusp (formerly referred to as CTI-1601), is a subcutaneously administered, recombinant fusion protein intended to deliver human frataxin (FXN), an essential protein to the mitochondria of patients with Friedreich’s ataxia. Friedreich’s ataxia is a rare, progressive, and fatal disease in which patients are unable to produce sufficient FXN due to genetic abnormality. The company has assembled an experienced management team, each of whom has over 20 years of pharmaceutical industry experience and has over 50 employees. Their management team, employees, and consultants have significant expertise in discovery, nonclinical and clinical development, regulatory affairs, and the development of manufacturing processes utilizing good manufacturing practices. The company’s strategy is to become a leader in the treatment of rare diseases by leveraging their technology platform and applying their team’s know-how to the development of nomlabofusp and other future pipeline projects. We are best characterized by entrepreneurial and scientific leadership and a participatory workforce committed to success. If you are searching for a company where urgency, agility, and commitment to science win the day – we welcome you![

Position Summary Larimar Therapeutics is seeking an experienced and highly motivated Analytical Scientist to provide scientific and strategic leadership for analytical development activities supporting a late-stage protein therapeutic. Reporting directly to the Head of Analytical Science and Technology, this individual will be responsible for establishing and executing analytical strategies and overseeing analytical method transfer, validation, and lifecycle management activities at external development and contract manufacturing organizations (CDMOs). The successful candidate will serve as a key technical leader across Drug Substance (DS) and Drug Product (DP) development, providing scientific oversight for analytical method development, qualification, validation, transfer, and ongoing method performance monitoring. This role will work closely with Process Development, Manufacturing, Quality, Regulatory Affairs, and external partners to ensure robust analytical support throughout product development and commercialization. The ideal candidate possesses deep expertise in protein therapeutic characterization and analytical control strategies, including hands-on experience with chromatographic, electrophoretic, and mass spectrometry-based analytical techniques used to support process development, release testing, comparability assessments, and stability programs. This individual will have a demonstrated track record of leading analytical activities for protein therapeutic programs from development through clinical manufacturing, with experience supporting regulatory submissions and health authority interactions. Experience serving in a CMC leadership role, such as Program Team Leader or CMC program Lead, is highly desirable.

Job Duties and Responsibilities

Analytical Development Leadership

Develop and execute analytical strategies to support the development, manufacture, characterization, and commercialization of protein therapeutics.
Provide scientific leadership and technical oversight for analytical method development, optimization, qualification, validation, transfer, and lifecycle management conducted internally and at contract laboratories.
Establish phase-appropriate analytical control strategies aligned with ICH guidelines, regulatory expectations, and product-specific risk assessments.
Lead analytical characterization programs, comparability assessments, forced degradation studies, stability studies, and product specification development activities.
Review and approve analytical methods, validation packages, technical reports, and supporting documentation ensuring compliance with cGMP and regulatory expectations.
Author and review SOPs and internal guidance documents to streamline business processes.
Drive scientific investigations related to analytical method performance, product quality attributes, and process-related changes.
Lead comparability assessments and critical quality attribute (CQA) evaluations to ensure process changes are appropriately assessed and maintained within established quality parameters.
Evaluate emerging analytical technologies and recommend approaches to strengthen product characterization and control strategies.

CMC and Program Leadership

Serve as the analytical sciences representative on cross-functional program and CMC teams.
Provide strategic input to process development, manufacturing, technology transfer, and product lifecycle management activities.
Lead or contribute to technical risk assessments and resolution of complex product, analytical, and process development challenges.
Provide oversight of analytical activities executed at CDMOs, contract laboratories, and external development partners.
Author, review, and approve technical documents, protocols, reports, regulatory filings, and responses to health authority inquiries.
Support regulatory submissions, agency interactions, inspections, and audit readiness activities.
Effectively communicate analytical development strategies, risks, and recommendations to internal stakeholders and senior management.

Requirements

Education and Experience

Bachelor’s degree in a relevant discipline and 15+ years of relevant professional experience; or
Master’s degree and 12+ years of relevant professional experience; or
Ph.D. and 8+ years of relevant professional experience.
Demonstrated experience leading analytical development activities supporting protein therapeutics in a biotechnology or pharmaceutical environment.
Experience supporting IND, BLA, MAA, or other global regulatory submissions.
Proven experience working with recombinant proteins, enzymes, fusion proteins, antibody fragments, or other protein-based therapeutics.
Experience managing analytical development, method transfer, and technology transfer activities at CDMOs and other external development partners.
Strong understanding of GxP regulations, quality systems, and pharmaceutical development principles.
Excellent leadership, communication, project management, and stakeholder management skills.
Ability to operate effectively in a fast-paced and evolving environment.
Demonstrated commitment to scientific excellence, continuous improvement, and collaborative problem-solving.

Technical Qualifications Candidates should possess hands-on experience developing, troubleshooting and qualifying, analytical methods commonly used for protein therapeutic development, including:

Size Exclusion Chromatography (SEC)
Reduced Capillary Electrophoresis Sodium Dodecyl Sulfate (rCE-SDS)
Non-Reduced Capillary Electrophoresis Sodium Dodecyl Sulfate (nrCE-SDS)
Reversed-Phase High-Performance Liquid Chromatography (RP-HPLC)
Ion Exchange Chromatography (IEX), including charge variant characterization
Peptide Mapping using LC-MS and/or UV detection

Strong understanding of protein structure-function relationships and advanced characterization techniques, including:

Analytical Ultracentrifugation (AUC)
Circular Dichroism (CD)
Differential Scanning Calorimetry (DSC)
Fourier Transform Infrared Spectroscopy (FTIR)
Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS)
Intact mass and peptide-level mass spectrometry characterization
Aggregation, fragmentation, oxidation, deamidation, glycation, and other protein degradation pathways

Benefits

Larimar Therapeutics offers all employees incentive stock options, a comprehensive benefits plan including 401K, and a flexible PTO policy.

We are committed to equal-employment principles, and we recognize the value of committed employees who feel they are being treated in an equitable and professional manner. We strive to find ways to attract, develop and retain the talent needed to meet business objectives, and to recruit and employ highly qualified individuals representing the diverse communities in which we live.

Employment policies and decisions on employment and promotion are based on merit, qualifications, performance, and business needs. The decisions and criteria governing the relationship with all candidates and employees are made in a non-discriminatory manner - without regard to age, race, color, national origin, gender (including pregnancy, childbirth or medical condition related to pregnancy or childbirth), gender identity or expression, religion, physical or mental disability, medical condition, legally protected genetic information, marital status, veteran status, military status, sexual orientation, or any other factor determined to be an unlawful basis for such decisions by federal, state, or local statutes.

Apply on recruiting.paylocity.com About employer

More about this job

Skills

Pharmaceutical industry
Regulatory affairs
Good manufacturing practices
Leadership
DP
Mass spectrometry
Documentation
Regulatory compliance
Business processes
Inspection
Biotechnology
Quality control systems
Communication skills
Project management
Stakeholder management
Process improvement
Problem solving
Troubleshooting

Report this job

Work requirements

Jobs in the United States