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CAR T-Cell Engineering Scientist

  • South San Francisco, CA, United States

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Job details

Posting language
English
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Original job description

Company Description Integrated resources is a staffing company

Job Description

  • The scientist will be involved in establishing methodologies, i.e. culturing and activating primary T-cells, enriching T-cell populations, viral transductions and electroporation of primary cells, to generate CAR T-cells.
  • They will also be responsible for CAR T-cells based on current state of the art and novel constructs in vitro and in vivo to identify optimal constructs and characteristics for therapeutic uses

Qualifications

  • BS and 5+ years of experience or MS and 3+ years of experience in an academic and/or industrial setting.
  • Knowledge and hands-on experience in generating and optimizing human CAR T-cells is required.
  • Knowledge and experience of modern laboratory methodology in cellular and molecular T-cell immunology.
  • Knowledge and experience with viral based systems (lenti-virus, adenovirus, or murine retrovirus) to optimize transduction of cell-lines and primary cells.
  • Knowledge and experience in genome engineering (zinc fingers, TALEN, or CRISPR) is preferred.
  • Excellent written, oral communication skills.
  • 4-7 years of experience in Biochemical techniques.
  • 4-7 years of experience in Cell/Tissue Culture techniques.

Additional Information

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Skills

  • Communication skills

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