Analytical Development Scientist

Job Description

Our large pharmaceutical client’s Cell & Gene Therapy Analytical Development team is seeking an experienced Scientist to support analytical method development and testing for in vivo CAR-T programs from early development through commercialization. This is a hands-on laboratory role in Malvern, PA with a primary focus on cell-based assays/bioassays and flow cytometry, supporting release, stability, and characterization activities. The ideal candidate will be an experienced scientist who can independently perform laboratory work, develop methods, and contribute to scientific and experimental design.

Key Responsibilities

-Develop and execute analytical methods supporting Cell & Gene Therapy programs. -Perform cell-based assays/bioassays, including cytotoxicity/killing assays, infectious titer assays, and other functional assays. -Design, develop, and execute multicolor flow cytometry panels and analyze/interpret resulting data. -Perform analytical testing supporting release, stability, and characterization activities. -Contribute to analytical method development, troubleshooting, and experimental design. -Support additional analytical technologies, including DLS, molecular methods, sequencing, and lentiviral methods as needed.

Skills and Requirements

-Cell & Gene Therapy and/or lentiviral/viral vector experience. -Experience with DLS, molecular assays, sequencing, and/or traditional PCR. -Experience supporting analytical methods across multiple stages of product development. -6+ years of relevant analytical development/laboratory experience for BS/MS-level candidates; PhD candidates with relevant industry experience strongly preferred. -Strong hands-on experience with cell-based assay/bioassay development and execution. -Strong hands-on flow cytometry experience, including designing and developing multicolor panels rather than solely executing established methods. -Previous experience in an analytical development laboratory. -Ability to independently perform laboratory testing and contribute to scientific/experimental design.

We are a company committed to creating diverse and inclusive environments where people can bring their full, authentic selves to work every day. We are an equal employment opportunity/affirmative action employer that believes everyone matters. Qualified candidates will receive consideration for employment without regard to race, color, ethnicity, religion, sex (including pregnancy), sexual orientation, gender identity and expression, marital status, national origin, ancestry, genetic factors, age, disability, protected veteran status, military or uniformed service member status, or any other status or characteristic protected by applicable laws, regulations, and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to HR@insightglobal.com.