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Security Engineer
E-Infosol LLC
Chantilly, VA
E-INFOSOL LLC is seeking a motivated and results-driven Security Engineer to join our growing team in Chantilly, VA
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Software Engineer 3
BHE
Reno, NV
…unit, system, automated testing, and post deployment validation design. Coordinates user acceptance…
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Software Engineer 3
BHE
Las Vegas, NV
…unit, system, automated testing, and post deployment validation design. Coordinates user acceptance…
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Senior Databricks Data Engineer
Securiport
Reston, VA
…analysis, certification, and compliance. The Senior Databricks Data Engineer will lead the design, development, and optimization of data pipelines and data platforms within a…
Added 1 min ago
SO
Geotech Transportation Engineering Associate I (61034972)
State of South Carolina
Richland County, SC
- $65,000 to $90,372 USD / year
…Engineering for the Upstate Regional Production Group, including design and analysis of foundations for bridges, roadway embankments and highway…
Added 1 min ago
Senior Application Analyst - Radiology
CORP - HM Corporate Division - The Methodist Hospital
United States
Expert ability and skill to troubleshoot system problems and to engineer expert solutions with IT customers and vendors
Added 1 min ago
HL
Construction Engineer
Hampton, Lenzini and Renwick, Inc.
Elgin, IL
- $95,000 to $120,000 USD / year
Hampton, Lenzini and Renwick, Inc. (HLR) of Elgin, IL is looking to hire a full-time Construction Engineer. Are you a civil engineering professional who is ready to take your career to the…
Added 1 min ago
Project Manager, Aviation
Leo A Daly LLC
Atlanta, GA
Professional Engineer (PE), Registered Architect, or CCM preferred.
Added 1 min ago
Project Manager, Aviation
Leo A Daly LLC
Miami, FL
Professional Engineer (PE), Registered Architect, or CCM preferred.
Added 1 min ago
Project Manager, Aviation
Leo A Daly LLC
Los Angeles, CA
Professional Engineer (PE), Registered Architect, or CCM preferred.
Added 1 min ago
Project Director, Aviation
Leo A Daly LLC
Atlanta, GA
Be a collaborative partner, providing innovative thinking into our projects, studio, and market delivery, promoting design research that advances our market strategy and be a leading voice…
Added 1 min ago
VT
Systems Administrator
VivSoft Technologies
Remote, United States
- $65,000 to $75,000 USD / year
Design and manage backup, disaster recovery and business continuity solutions
Added 2 mins ago
CE
Engineering Intern - Civil/Design (51564)
Collins Engineers, Inc
Milwaukee, WI
- $26 to $28 USD / hour
…training to a meaningful work experience with our civil site design group in Milwaukee, WI for the Summer 2027. During this time, the successful candidate will gain hands-on experience…
Added 3 mins ago
Civil Engineer EIT
Actalent
Blue Bell, PA
Job Title: Civil EngineerJob DescriptionThis role offers an opportunity for a motivated Civil Engineer to contribute to a wide range of land development and infrastructure projects, with a…
Added 3 mins ago
A
Electrical Engineer
Actalent
Scottsdale, AZ
- $90,000 to $120,000 USD / year
Job Title: Electrical EngineerJob DescriptionThe Electrical Engineer develops, maintains, and troubleshoots test equipment for medical devices, ensuring that all products meet rigorous…
Added 3 mins ago
A
Quality Control Mechanical Engineer
Actalent
Columbus, OH
- $25 to $30 USD / hour
Knowledge of plumbing design and tape measure use.
Added 3 mins ago
Transmission Line Design Engineer 3
Actalent
Forest Park, GA
Job TitleTransmission Line Design Engineer 3Job DescriptionThe Line Design Engineer 3 designs and delivers high-voltage transmission line facilities, applying advanced engineering…
Added 3 mins ago
A
Controls Engineer
Actalent
Atlanta, GA
- $30 to $55 USD / hour
Job Title: Controls EngineerJob DescriptionThe Controls Engineer designs and develops PLC programs for material handling and warehouse automation equipment. This role participates in all…
Added 3 mins ago
Sr. Molding Engineer - Plastics
Actalent
Buffalo Grove, IL
The Sr. Molding Engineer will develop, optimize, validate, and troubleshoot plastic molding processes. This role will focus on improving process capability, cycle time, scrap, yield, and…
Added 3 mins ago
A
Mechanical Engineer
Actalent
Carol Stream, IL
- $40 to $55 USD / hour
We are seeking a Mechanical Engineer to design and develop electromechanical products from concept through manufacturing. This role combines mechanical design, electronics integration,…
Added 3 mins ago
Process Engineer
Actalent
Eden Prairie, MN
Job Title: Process EngineerJob DescriptionThe Process Engineer supports and leads daily production line activities and continuous improvement initiatives within a manufacturing environment.…
Added 3 mins ago
Mechanical Engineer
Actalent
Eden Prairie, MN
Job Title: Mechanical EngineerJob DescriptionThe Mechanical Engineer designs and develops innovative mechanical and electro-mechanical components and sub-systems for industrial and…
Added 3 mins ago
Design Engineer
Actalent
Bettendorf, IA
Job Title: Design EngineerJob DescriptionThe Design Engineer supports aluminum foundry and machining operations by designing and modifying permanent molds, foundry patterns, machining…
Added 3 mins ago
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Electrical Engineer
Actalent
Marion, IA
- $65,000 to $140,000 USD / year
Job Title: Electrical EngineerJob DescriptionThis leadership-level Electrical Engineer role sits within a multi-discipline electrical and power team and serves as a key technical resource…
Added 3 mins ago
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Hardware Test Engineer
Actalent
Pella, IA
- $40 to $48 USD / hour
Job Title: Hardware Test EngineerJob DescriptionThe Hardware Test Engineer designs, executes, and supports hardware and software test activities for production and compliance, with a focus…

Hologic

Software AI Engineer 4

Marlborough, MA, United States
San Diego, CA, United States

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Job details

Posting language: English
Posted: Nov 9, 2026

Original job description

At Hologic, we are driven by a singular purpose: to enable healthier lives everywhere, every day. As a global leader in women’s health, we design innovative diagnostic and imaging solutions that help detect disease earlier and improve outcomes for patients worldwide. Join a team where your work in AI and digital diagnostics directly supports clinicians in delivering better care for women.

Job Summary Hologic is seeking a Software Algorithm Engineer 4 to design, train and validate deep learning models for cytology on the Genius™ Digital Diagnostics System. This role owns the cell-level CNN classifier, nuclear-to-cytoplasmic (NC) ratio segmentation pipeline, and the technical evidence needed to support FDA and other regulatory submissions. The engineer serves as the technical lead for model design and verification under design controls, working closely with cytopathologists, imaging scientists, regulatory and quality teams.

Key Responsibilities

Design, train and tune multi-class CNNs to classify cells and aggregate predictions into specimen-level diagnostic categories.
Develop multi-task models with shared encoders and feature heads for diagnostic class, cytomorphologic features and NC ratio category.
Build nucleus and cytoplasm segmentation networks to measure NC ratio and nuclear area, including overlapping cells in clusters.
Own the data pipeline, including patient-grouped splits, color profile application, class balance and imaging metadata.
Run disciplined experiments, benchmark lightweight backbones against larger reference models and define evaluation metrics and reports.
Collaborate with pathologists on labeling protocols, inter-observer agreement and adjudication processes.
Prepare design documentation, verification/validation protocols and technical content for regulatory submissions.
Mentor engineers and establish coding, reproducibility and MLOps standards.
Ensure model performance and interpretability, including Grad-CAM checks and feature outputs that align with pathologist expectations.
Support regulatory strategy for AI-enabled medical devices under design controls and PCCP guidance.

Qualifications

Education

MS or PhD in computer science, biomedical engineering, electrical engineering or a related field, or BS with equivalent experience.

Experience

7+ years of software development, including 4+ years building and deploying deep learning models for computer vision.

•

Coaching and mentorship experience a plus

Skills

Expert Python and PyTorch (or TensorFlow), including CNN fine-tuning, transfer learning and segmentation (e.g., U-Net, segmentation_models_pytorch).
Experience with imbalanced, multi-class and multi-task problems, and metrics such as per-class sensitivity, F1, kappa and AUROC.
Experience with medical or microscopy imaging, including color handling, stain variation and high-resolution tiling.
Strong discipline in data splitting, leakage prevention, experiment tracking and reproducible training.
Clear written communication for technical reports and design documentation.
Preferred: digital pathology or cytology AI experience (ideally urine cytology); experience with FDA 510(k), De Novo, PMA or EU IVDR; familiarity with IEC 62304, ISO 13485, ISO 14971, 21 CFR Part 820 and FDA PCCP guidance.
Preferred: ICC color management, stain deconvolution and scanner color calibration; cell instance segmentation tools (StarDist, Cellpose) and annotation tools (QuPath, CVAT, napari).
Preferred: model optimization for edge or embedded inference (quantization, ONNX, TensorRT) and experience leading or technically guiding a small team.

Why join Hologic?

We are committed to making Hologic the destination for top talent. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career.

The annualized base salary range for this role is $133,000 - $190,000 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, education, business needs and market demand.

Agency and Third-Party Recruiter Notice

Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition, Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.

Hologic is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.

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More about this job

Skills

Deep learning
Documentation
Medical devices
Computer science
Biomedical engineering
Electrical engineering
Software development
Coaching
Python
PyTorch
TensorFlow
Communication skills

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