Jobs in the United States

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VA
Delivery Driver & Inventory Specialist
Value Added Distributors LLC
Rockford, IL
- From $18 USD / hour
Benefits include health, dental, and vision insurance, paid vacation and holidays, and a 401(k) plan with employer match.
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Principle Coatings Engineer (Onsite)
RTX
United States
…new/repair technology development, cost reduction, etc. where the engineer will understand customer requirements and execute development programs to meet and exceed business…
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Senior Engineer, Maintenance, Repair, and Overhaul Engineering, Hot Section Engineering P2 (Onsite)
RTX
United States
Hired applicants may be eligible for benefits, including but not limited to, medical, dental, vision, life insurance, short-term disability, long-term disability, 401(k) match, flexible…
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Product Quality Engineer I (Onsite)
RTX
United States
The Product Quality Engineer will provide support to ensure compliance with contractual, company, and regulatory requirements. Apply Engineering skills to develop and deploy effective and…
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Senior Integration and Test Systems Engineer - Secure Systems
RTX
United States
The High Assurance Devices Engineering team seeks a Senior Integration and Test Systems Engineer with a passion for embedded systems and hands-on problem solving. In this role, you will…
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Principal Specialist, Industrial Engineer (Onsite)
RTX
United States
Collins Aerospace is seeking a Senior Industrial Engineer to support top-level assembly operations and drive manufacturing excellence in a high-volume production environment. This role…
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SPY-6 Radar - Senior Software Integration Engineer
RTX
United States
…seeking a highly motivated and skilled Radar Software Integration Engineer to join the SPY-6 Family of Radars Software Operations team. The ideal candidate will collaborate with…
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Manufacturing Engineer
RTX
United States
The Manufacturing Automation Engineer will lead the implementation and optimization of robotic welding and automation within commercial heat exchanger manufacturing, including process…
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Integration & Test Systems Engineer II - Secure Systems
RTX
United States
The High Assurance Devices Engineering team seeks an early-career Integration and Test Systems Engineer II with a passion for embedded systems and hands-on problem solving. In this role,…
Added 2 mins ago
SC
Analytics Engineer
Smart Circle International
Remote, United States
- $100,000 to $125,000 USD / year
The Analytics Engineer bridges business stakeholders, BI, and Data Engineering teams. This role focuses on designing scalable data solutions, building business-ready data models, and…
Added 2 mins ago
IT Applications Engineer
Potawatomi Hotel & Casino
Milwaukee, WI
In this fast-paced, high-energy environment, the IT Applications Engineer is essential to keeping our critical information technology systems up, up-to-date and running smoothly. Working…
Added 3 mins ago
Manufacturing Electrical Equipment Engineer
Detroit Diesel Corporation
Detroit, MI
…machining operations for heavy-duty engines. As a Controls Engineer, you will play a critical role in ensuring the reliability, performance, and continuous improvement of machining and…
Added 3 mins ago
T
Applied AI Engineer II
Tanium
Addison, TX · Durham, NC
- $154,000 to $236,000 USD / year
As a Tanium Applied AI Engineer II, you will be tasked with building and maintaining best-of-breed products as part of a small and nimble development team. Tanium focuses on a strong…
Added 5 mins ago
Principal Automation Engineer Optical Inspection SME
Janssen Biotech, Inc. Legal Entity
Wilson, NC
Senior Automation Engineer will lead internal team members, suppliers, OEMs, system integrators, Digital/IT partners, automation-system owners, and cross-functional stakeholders to deliver…
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Software Engineer I
Chewy
Boston, MA · Plantation, FL
Chewy is seeking a Software Engineer I to join an established technology team in Boston, MA. At Chewy, it is our mission to be the most trusted and convenient destination for pet parents…
Added 7 mins ago
Product Development Engineer - RWD Transmission Systems Quality Engineer
Ford Global
Livonia, MI
This is the 10-speed transmission systems engineer position responsible for design, validation, and vehicle integration for all RWD Medium Duty Transmission programs. We are looking for…
Added 8 mins ago
O
Principal Platform Software Engineer - Oracle Health
Oracle
United States
- $105,900 to $234,600 USD / year
8+ years of professional software development experience, including significant experience in both front-end and backend application development.
Added 8 mins ago
AC
Data Engineer
Aston Carter
Dallas, TX
- $60 to $67 USD / hour
Job Title: Data EngineerJob DescriptionThe Data Engineer will play a key role in the continued development and modernization of the organizations data environment, with a focus on creating…
Added 9 mins ago
Mechanical Engineer
Actalent
Coral Springs, FL
We are seeking a Mechanical Engineer to join our growing Product Development team in Coral Springs, FL. This is an exciting opportunity to work on innovative products from concept through…
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Electrical Engineer
Actalent
Vancouver, WA
This Electrical Engineer position will provide support to the Transmission Line Engineering (TELC) organization at Bonneville Power Administration (BPA). The Electrical Effects Engineer in…
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Junior Engineer
Actalent
Halethorpe, MD
Job Title: Junior EngineerJob DescriptionThis entry-level Junior Engineer role supports engineers in developing, refining, and optimizing programs and processes for new production and…
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Project Engineer
Actalent
Versailles, KY
Project Engineer - Natural Gas Pipelines & Metering Stations
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A
Senior Manufacturing Engineer
Actalent
Delano, MN
- $80,000 to $120,000 USD / year
Job Title: Manufacturing EngineerJob DescriptionThe higher level Manufacturing Engineer plays a key role in developing, optimizing, and supporting manufacturing processes for medical device…
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A
Manufacturing Engineer
Actalent
Rochester, MN
- $38 to $55 USD / hour
Job Title: Manufacturing Engineer (Level II)Job DescriptionThis role leads the manufacturing lifecycle of products from prototype through pilot and full production, ensuring robust…
Added 9 mins ago
A
Substation Engineer
Actalent
Austin, TX
- $55 to $70 USD / hour
Job Title: Substation EngineerJob DescriptionThis role is for an experienced Substation / Protection & Control (P&C) Engineer based in Houston, Texas. The engineer will lead and execute…

Hologic

Principal Software Algorithm Engineer - Digital Cytology AI

Marlborough, MA, United States

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Job details

Posting language: English
Posted: Nov 6, 2026

Original job description

At Hologic, we are driven by a singular purpose: to enable healthier lives everywhere, every day. As a global leader in women’s health, we design innovative diagnostic and imaging solutions that help detect disease earlier and improve outcomes for patients worldwide. Join a team where your work in AI and digital diagnostics directly supports clinicians in delivering better care for women.

Job Summary Hologic is seeking a Principal Software Algorithm Engineer to design, train and validate deep learning models for cytology on the Genius™ Digital Diagnostics System. This role owns the cell-level CNN classifier, nuclear-to-cytoplasmic (NC) ratio segmentation pipeline, and the technical evidence needed to support FDA and other regulatory submissions. The engineer serves as the technical lead for model design and verification under design controls, working closely with cytopathologists, imaging scientists, regulatory and quality teams.

Key Responsibilities

Design, train and tune multi-class CNNs to classify cells and aggregate predictions into specimen-level diagnostic categories.
Develop multi-task models with shared encoders and feature heads for diagnostic class, cytomorphologic features and NC ratio category.
Build nucleus and cytoplasm segmentation networks to measure NC ratio and nuclear area, including overlapping cells in clusters.
Own the data pipeline, including patient-grouped splits, color profile application, class balance and imaging metadata.
Run disciplined experiments, benchmark lightweight backbones against larger reference models and define evaluation metrics and reports.
Collaborate with pathologists on labeling protocols, inter-observer agreement and adjudication processes.
Prepare design documentation, verification/validation protocols and technical content for regulatory submissions.
Mentor engineers and establish coding, reproducibility and MLOps standards.
Ensure model performance and interpretability, including Grad-CAM checks and feature outputs that align with pathologist expectations.
Support regulatory strategy for AI-enabled medical devices under design controls and PCCP guidance.

Qualifications

Education

MS or PhD in computer science, biomedical engineering, electrical engineering or a related field, or BS with equivalent experience.

Experience

10+ years of software development, including 5+ years building and deploying deep learning models for computer vision.

•

Demonstrated leadership experience, with the ability to set strategic direction, influence senior stakeholders, lead cross-functional initiatives, and drive accountability and execution in a complex, matrixed organization.

Skills

Expert Python and PyTorch (or TensorFlow), including CNN fine-tuning, transfer learning and segmentation (e.g., U-Net, segmentation_models_pytorch).
Experience with imbalanced, multi-class and multi-task problems, and metrics such as per-class sensitivity, F1, kappa and AUROC.
Experience with medical or microscopy imaging, including color handling, stain variation and high-resolution tiling.
Strong discipline in data splitting, leakage prevention, experiment tracking and reproducible training.
Clear written communication for technical reports and design documentation.
Preferred: digital pathology or cytology AI experience (ideally urine cytology); experience with FDA 510(k), De Novo, PMA or EU IVDR; familiarity with IEC 62304, ISO 13485, ISO 14971, 21 CFR Part 820 and FDA PCCP guidance.
Preferred: ICC color management, stain deconvolution and scanner color calibration; cell instance segmentation tools (StarDist, Cellpose) and annotation tools (QuPath, CVAT, napari).
Preferred: model optimization for edge or embedded inference (quantization, ONNX, TensorRT) and experience leading or technically guiding a small team.

Why join Hologic?

We are committed to making Hologic the destination for top talent. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career.

The annualized base salary range for this role is $157,000 - $220,000 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, education, business needs and market demand.

Agency and Third-Party Recruiter Notice

Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition, Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.

Hologic is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.

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More about this job

Skills

Deep learning
Documentation
Medical devices
Computer science
Biomedical engineering
Electrical engineering
Software development
Leadership
Python
PyTorch
TensorFlow
Communication skills

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