Jobs in the United States

25+ jobs

Save this search

Added 1 min ago
Test Coordinator
CACI
Fort Belvoir, VA · Fort Belvoir
As a test engineer supporting Product Manager Soldier Tactical Reconnaissance, Intelligence and Kinetic Effects (STRIKE) within the Portfolio Acquisition Executive Layered Protection you…
Added 1 min ago
Senior Project Engineer, Mechanical Systems Externals and Nacelles (Onsite)
RTX
United States
As a Senior Project Engineer, you will provide leadership and project management to a cross‑functional Integrated Product Team (IPT) responsible for part‑level ownership throughout the…
Added 2 mins ago
Senior Applications Engineer
Safran
Rochester, NY
Travel nationwide to provide onsite support and execution, not limited to a single region
Added 2 mins ago
AWS DevOps Engineer
Stefanini Group
San Francisco, CA
Stefanini is looking for an AWS DevOps Engineer -Remote
Added 3 mins ago
IT Applications Engineer
Potawatomi Hotel & Casino
Milwaukee, WI
In this fast-paced, high-energy environment, the IT Applications Engineer is essential to keeping our critical information technology systems up, up-to-date and running smoothly. Working…
Added 5 mins ago
Sr Eng Process Engineering
Ethicon Inc. Legal Entity
Memphis, TN
We are searching for the best talent for Sr Engineer Process Engineering
Added 9 mins ago
Project Executive- Director of Project Excellence
Kelso Industries
Jackson, GA
…strategic direction, financial performance, and operational execution of commercial and industrial electrical construction projects. This role oversees multiple projects and project teams,…
Added 10 mins ago
Chief Engineer
Voyager Technologies, Inc.
Remote, United States
The Chief Engineer for Strategic Systems is an autonomous technical leader responsible for the end-to-end mission success of solid rocket propulsion system programs by managing large…
Added 10 mins ago
Project Engineer
Actalent
Versailles, KY
Project Engineer - Natural Gas Pipelines & Metering Stations
Added 10 mins ago
A
Systems Engineer
Actalent
Cedar Rapids, IA
- $60 to $65 USD / hour
Job Title: Systems EngineerJob DescriptionThis Systems Engineer role offers the opportunity to serve as a technical leader for complex, safety-critical systems, with a focus on avionics and…
Added 11 mins ago
Project Engineer II
CRB
Columbus, OH
The Project Engineer II supports the Project Manager and broader construction team in the planning, coordination, and execution of assigned projects. This role helps maintain alignment…
Added 11 mins ago
TS
EMC Test Engineer (3rd shift and weekends) 1 1
TUV SUD America
New Brighton, MN
- $75,000 to $90,000 USD / year
As an EMC Test Engineer, you will perform electromagnetic compatibility (EMC) testing and evaluations for a wide range of products to support global regulatory compliance and certification…
Added 11 mins ago
Senior Electrical Design Engineer
RMS Energy
Little Falls, MN
Support project execution by coordinating with field teams, reviewing installations, and participating in commissioning
Added 11 mins ago
Environmental Program Leader – Hazardous Waste and Dangerous Goods Compliance
GE Aerospace
Minnetonka, MN
…requirements into clear, practical, and scalable processes that support both compliance excellence and operational…
Added 11 mins ago
WC
ENGINEERING MANAGER
Wells Concrete Products, Inc.
Maple Grove, MN
- $130,000 to $170,000 USD / year
…alignment with organizational goals. This role oversees technical execution, project performance, and cross-functional collaboration to deliver safe, efficient, and timely project outcomes.…
Added 11 mins ago
Mechanical Engineering Co-Op
Emerson
Eden Prairie, MN
Partner directly with a lead mechanical engineer to support new product development and ongoing product improvement initiatives.
Added 11 mins ago
Electrical Engineer - Power System Protection (Transmission) Job Details | Black & Veatch Family of Companies
Black & Veatch
Bloomington, MN
Electrical Engineer - Power System Protection (Transmission)
Added 11 mins ago
Senior Geothermal Consultant Job Details | Black & Veatch Family of Companies
Black & Veatch
Bloomington, MN
Support Owner’s Engineer / Independent Engineer scopes through disciplined technical review.
Added 11 mins ago
Enterprise Account Project Coordinator III (Remote, USA)
Medtronic
Minneapolis, MN
This position provides project coordination, administrative, and operational support to Enterprise Account Managers and Account Program Managers within the Global Commercial Office. The…
Added 11 mins ago
Field Engineer for Water Treatment at Data Centers
Garratt Callahan Co
Amarillo, TX
A Water Treatment Field Engineer will be based in Amarillo, Texas, and responsible for supporting data centers primarily in the Texas Panhandle. The Field Engineer will solve customer water…
Added 12 mins ago
T
Adobe Analytics Engineer
TEKsystems
Minneapolis, MN
- $45 to $75 USD / hour
Our client is seeking an Analytics Engineer to join its Digital Analytics team supporting enterprise tracking, analytics, and personalization initiatives.
Added 12 mins ago
IC
Mechanical Engineering New Graduate | Minneapolis, MN
IMEG Consultants Corp.
Minneapolis, MN
- $11.41 USD / hour
Support the execution of consulting projects as part of a project team, including assisting with project planning and scheduling to meet project deadlines and objectives.
Added 12 mins ago
Senior Contract Manager, Enterprise Accounts - Minneapolis, MN
Medtronic
Fridley, MN · Minneapolis, MN
The Americas Pricing & Contracting function develops and executes commercial strategies that support profitable growth across Medtronic’s U.S. businesses. The team partners with Sales,…
Added 12 mins ago
Senior Embedded Software Engineer
Trane Technologies
Minneapolis, MN
Participate in the core execution phases of the software development lifecycle from low-level design through integration, unit/integration testing, deployment, and manufacturing support.
Added 12 mins ago
Senior Software Engineer - Incentive Compensation
Wells Fargo
MINNEAPOLIS, MN
The Human Resources Information Technology (HRIT) team provides technology support for team member focused applications and processes, including payroll, benefits, learning and recruiting.…

Hologic

Principal Software Algorithm Engineer - Digital Cytology AI

Marlborough, MA, United States

Apply About employer

Applications open in a new tab.

Job details

Posting language: English
Posted: Nov 6, 2026

Original job description

At Hologic, we are driven by a singular purpose: to enable healthier lives everywhere, every day. As a global leader in women’s health, we design innovative diagnostic and imaging solutions that help detect disease earlier and improve outcomes for patients worldwide. Join a team where your work in AI and digital diagnostics directly supports clinicians in delivering better care for women.

Job Summary Hologic is seeking a Principal Software Algorithm Engineer to design, train and validate deep learning models for cytology on the Genius™ Digital Diagnostics System. This role owns the cell-level CNN classifier, nuclear-to-cytoplasmic (NC) ratio segmentation pipeline, and the technical evidence needed to support FDA and other regulatory submissions. The engineer serves as the technical lead for model design and verification under design controls, working closely with cytopathologists, imaging scientists, regulatory and quality teams.

Key Responsibilities

Design, train and tune multi-class CNNs to classify cells and aggregate predictions into specimen-level diagnostic categories.
Develop multi-task models with shared encoders and feature heads for diagnostic class, cytomorphologic features and NC ratio category.
Build nucleus and cytoplasm segmentation networks to measure NC ratio and nuclear area, including overlapping cells in clusters.
Own the data pipeline, including patient-grouped splits, color profile application, class balance and imaging metadata.
Run disciplined experiments, benchmark lightweight backbones against larger reference models and define evaluation metrics and reports.
Collaborate with pathologists on labeling protocols, inter-observer agreement and adjudication processes.
Prepare design documentation, verification/validation protocols and technical content for regulatory submissions.
Mentor engineers and establish coding, reproducibility and MLOps standards.
Ensure model performance and interpretability, including Grad-CAM checks and feature outputs that align with pathologist expectations.
Support regulatory strategy for AI-enabled medical devices under design controls and PCCP guidance.

Qualifications

Education

MS or PhD in computer science, biomedical engineering, electrical engineering or a related field, or BS with equivalent experience.

Experience

10+ years of software development, including 5+ years building and deploying deep learning models for computer vision.

•

Demonstrated leadership experience, with the ability to set strategic direction, influence senior stakeholders, lead cross-functional initiatives, and drive accountability and execution in a complex, matrixed organization.

Skills

Expert Python and PyTorch (or TensorFlow), including CNN fine-tuning, transfer learning and segmentation (e.g., U-Net, segmentation_models_pytorch).
Experience with imbalanced, multi-class and multi-task problems, and metrics such as per-class sensitivity, F1, kappa and AUROC.
Experience with medical or microscopy imaging, including color handling, stain variation and high-resolution tiling.
Strong discipline in data splitting, leakage prevention, experiment tracking and reproducible training.
Clear written communication for technical reports and design documentation.
Preferred: digital pathology or cytology AI experience (ideally urine cytology); experience with FDA 510(k), De Novo, PMA or EU IVDR; familiarity with IEC 62304, ISO 13485, ISO 14971, 21 CFR Part 820 and FDA PCCP guidance.
Preferred: ICC color management, stain deconvolution and scanner color calibration; cell instance segmentation tools (StarDist, Cellpose) and annotation tools (QuPath, CVAT, napari).
Preferred: model optimization for edge or embedded inference (quantization, ONNX, TensorRT) and experience leading or technically guiding a small team.

Why join Hologic?

We are committed to making Hologic the destination for top talent. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career.

The annualized base salary range for this role is $157,000 - $220,000 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, education, business needs and market demand.

Agency and Third-Party Recruiter Notice

Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition, Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.

Hologic is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.

Apply About employer

More about this job

Skills

Deep learning
Documentation
Medical devices
Computer science
Biomedical engineering
Electrical engineering
Software development
Leadership
Python
PyTorch
TensorFlow
Communication skills

Report this job