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Senior Sales Engineer, Enterprise
Fivetran
Remote, United States
We’re looking for a talented Senior Sales Engineer to join our Enterprise, Existing Business sales team. As an Enterprise Sales Engineer, you will work closely with our sales team to…
Added 1 min ago
8
Forward Deployed Engineer
8am
Austin, TX
- $170,000 to $200,000 USD / year
As a Forward Deployed Engineer at 8am, you embed directly with an internal business function - starting in Customer Support, Sales, Marketing, or Finance - to ship production agentic…
Added 3 mins ago
Senior Software & AI Engineer
St. Jude Medical, Cardiology Division, I
CA
The Senior Software & AI Engineer position works onsite in Sylmar, California within Abbott's Cardiac Rhythm Management (CRM) business.
Added 5 mins ago
Senior Software Engineer, Business Map
Toast
Remote, United States
Title: Senior Software Engineer, Business Map
Added 5 mins ago
C
Product Enablement Manager
Crunchtime
Atlanta, GA · Boston, MA
- $80,000 to $112,000 USD / year
5+ years of experience as a Sales Engineer, Solutions Consultant, TAM, or in technical/product enablement within a B2B SaaS environment.
Added 5 mins ago
Supply Chain Analytics Engineer II
Dick's Merch & Supply Chain, Inc
United States
The Analytics Engineer II bridges business operations, Data Engineering, and Business Intelligence by applying knowledge of Supply Chain processes, system workflows, and data relationships…
Added 5 mins ago
Design Systems Engineer - Turbomachinery
Aerospace
Phoenix, AZ
As a Design Systems Engineer – Turbomachinery here at Honeywell Aerospace, you will join the industry leader to design the next generation of breakthrough technologies!
Added 5 mins ago
Vice President of Technology
WorldVia
Remote, United States
…planning, coding, testing, code review, and deployment under engineer…
Added 6 mins ago
Principal Design Engineer
Astera Labs
San Jose, CA · CA
Added 6 mins ago
Software Engineer - AI Tooling
IMC
United States
We are seeking a Software Engineer based in Chicago to build the software behind IMC’s AI-powered engineering workflows. Your work will span agent harnesses, developer workspaces, context…
Added 8 mins ago
Senior MLOps Engineer
Fisher Investments
Tampa, FL
…our international growth. We are looking for a Senior MLOps Engineer to build the infrastructure, pipelines, and operational practices that bring machine learning and generative AI…
Added 8 mins ago
AI Engineer
Fisher Investments
Tampa, FL
…support our international growth. We are looking for a Software Engineer who will design, build, and improve advanced AI applications using large language models, GPU‑accelerated computing,…
Added 8 mins ago
FT
Mid-Level Business Intelligence Developer
Fusion Technology
Washington, DC
- $81,000 to $86,000 USD / year
…Information Services Division's Headquarters. Founded in 2007 by an Engineer-by-trade, Fusion Technology dedicates our valuable resources to providing comprehensive IT services and…
Added 9 mins ago
Project Engineer - Land Development
Atwell, LLC
Madison, WI
The Project Engineer leads design efforts for land development projects, provides technical expertise, and helps maintain project budgets and schedules. This role works with clients and…
Added 10 mins ago
Senior Technical Services Engineer
EnsoData
Remote, United States
EnsoData is seeking a Senior Technical Services Engineer (Healthcare and/or Software as a Medical Device - SaMD) to contribute to our customer-facing technical services team, ensuring the…
Added 11 mins ago
Senior Pre-Sales Infrastructure/Network Design Engineer
ewminds consulting Services
New York, NY
Added 11 mins ago
Vice President – Full Java Stack Engineer
ewminds consulting Services
Pittsburgh, PA
We are seeking a Vice President – Full Stack Engineer to join a mission-critical engineering team supporting a high-performance, regulated enterprise platform. This is a hands-on…
Added 11 mins ago
Senior Forward Deployed Engineer (FDE Lead
ewminds consulting Services
East Pittsburgh, PA
Added 11 mins ago
Senior DevSecOps Engineer
LEIDOS, INC.
Gaithersburg, MD · Eagan, MN · Egg Harbor Township, NJ
Leidos is seeking a Senior DevSecOps Engineer to join the Air Traffic Business Area within the Homeland Sector, supporting the development of the Leidos Common Automation Platform (L-CAP).…
Added 12 mins ago
Engineer III/Sr
Williams Companies
Tulsa, OK
As an Engineer Sr, you will conduct technical and economic evaluations, performance testing, design and construction of new and existing facilities, and research on new developments,…
Added 12 mins ago
EG
QA Automation Engineer
Eliassen Group
Oklahoma City, OK
- $75 to $82 USD / hour
Experience as an Automation Engineer using tools such as Selenium with Java or similar.
Added 12 mins ago
EG
Staff AI & Data Engineer – Databricks
Eliassen Group
Oklahoma City, OK
- $80 to $90 USD / hour
Our client is seeking a highly experienced Staff AI & Data Engineer to design and build enterprise-grade data and AI solutions on Databricks. This hands-on role focuses on strengthening the…
Added 13 mins ago
Web Developer
CACI
Chantilly, VA · Chantilly
AWS certification, such as AWS Certified Developer – Associate or AWS Certified DevOps Engineer – Professional.
Added 15 mins ago
AI Ops Engineer
OPEN OPENLANE US Inc
Remote, United States
…keeps them available, secure and cost-controlled. As an AI-Ops Engineer, you will administer our enterprise AI platforms, support the employees who use them, and automate the provisioning,…
Added 15 mins ago
SC
Analytics Engineer
Smart Circle International
Remote, United States
- $100,000 to $125,000 USD / year
The Analytics Engineer bridges business stakeholders, BI, and Data Engineering teams. This role focuses on designing scalable data solutions, building business-ready data models, and…

Hologic

Principal Software Algorithm Engineer - Digital Cytology AI

Marlborough, MA, United States

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Job details

Posting language: English
Posted: Nov 6, 2026

Original job description

At Hologic, we are driven by a singular purpose: to enable healthier lives everywhere, every day. As a global leader in women’s health, we design innovative diagnostic and imaging solutions that help detect disease earlier and improve outcomes for patients worldwide. Join a team where your work in AI and digital diagnostics directly supports clinicians in delivering better care for women.

Job Summary Hologic is seeking a Principal Software Algorithm Engineer to design, train and validate deep learning models for cytology on the Genius™ Digital Diagnostics System. This role owns the cell-level CNN classifier, nuclear-to-cytoplasmic (NC) ratio segmentation pipeline, and the technical evidence needed to support FDA and other regulatory submissions. The engineer serves as the technical lead for model design and verification under design controls, working closely with cytopathologists, imaging scientists, regulatory and quality teams.

Key Responsibilities

Design, train and tune multi-class CNNs to classify cells and aggregate predictions into specimen-level diagnostic categories.
Develop multi-task models with shared encoders and feature heads for diagnostic class, cytomorphologic features and NC ratio category.
Build nucleus and cytoplasm segmentation networks to measure NC ratio and nuclear area, including overlapping cells in clusters.
Own the data pipeline, including patient-grouped splits, color profile application, class balance and imaging metadata.
Run disciplined experiments, benchmark lightweight backbones against larger reference models and define evaluation metrics and reports.
Collaborate with pathologists on labeling protocols, inter-observer agreement and adjudication processes.
Prepare design documentation, verification/validation protocols and technical content for regulatory submissions.
Mentor engineers and establish coding, reproducibility and MLOps standards.
Ensure model performance and interpretability, including Grad-CAM checks and feature outputs that align with pathologist expectations.
Support regulatory strategy for AI-enabled medical devices under design controls and PCCP guidance.

Qualifications

Education

MS or PhD in computer science, biomedical engineering, electrical engineering or a related field, or BS with equivalent experience.

Experience

10+ years of software development, including 5+ years building and deploying deep learning models for computer vision.

•

Demonstrated leadership experience, with the ability to set strategic direction, influence senior stakeholders, lead cross-functional initiatives, and drive accountability and execution in a complex, matrixed organization.

Skills

Expert Python and PyTorch (or TensorFlow), including CNN fine-tuning, transfer learning and segmentation (e.g., U-Net, segmentation_models_pytorch).
Experience with imbalanced, multi-class and multi-task problems, and metrics such as per-class sensitivity, F1, kappa and AUROC.
Experience with medical or microscopy imaging, including color handling, stain variation and high-resolution tiling.
Strong discipline in data splitting, leakage prevention, experiment tracking and reproducible training.
Clear written communication for technical reports and design documentation.
Preferred: digital pathology or cytology AI experience (ideally urine cytology); experience with FDA 510(k), De Novo, PMA or EU IVDR; familiarity with IEC 62304, ISO 13485, ISO 14971, 21 CFR Part 820 and FDA PCCP guidance.
Preferred: ICC color management, stain deconvolution and scanner color calibration; cell instance segmentation tools (StarDist, Cellpose) and annotation tools (QuPath, CVAT, napari).
Preferred: model optimization for edge or embedded inference (quantization, ONNX, TensorRT) and experience leading or technically guiding a small team.

Why join Hologic?

We are committed to making Hologic the destination for top talent. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career.

The annualized base salary range for this role is $157,000 - $220,000 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, education, business needs and market demand.

Agency and Third-Party Recruiter Notice

Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition, Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.

Hologic is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.

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More about this job

Skills

Deep learning
Documentation
Medical devices
Computer science
Biomedical engineering
Electrical engineering
Software development
Leadership
Python
PyTorch
TensorFlow
Communication skills

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