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Engineering Project Manager Senior
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Added 4 mins ago
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Assoc Dir, Program and Project Management
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The Associate Director of Program and Project Management is a strategic leadership position within the Infrastructure & Operations (I&O) organization. This role is responsible for…
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Added 5 mins ago
Technical Program Management III Senior
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Senior Manager, Revenue Management Core Brands
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Sr Instructional Designer/ Curriculum Developer
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Automation Engineering, Sr. Engineer – Pharmaceutical Manufacturing - Lilly Medicine Foundry
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Director/Principal, Real-world Data and Healthcare Analytics Lead
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GSK

Senior Scientist, Upstream Processing

King of Prussia, PA, United States

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Job details

Experience: A minimum of 3 years of direct GMP manufacturing experience or upstream processing experience in a biotechnology manufacturing facility or Pilot Plant.
Posting language: English
Posted: Nov 9, 2026

Original job description

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programs, pension plan membership, and shares and savings programme. We embrace modern work practices; our Performance with Choice programme offers a remote or hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company-wide benefits and life at GSK on our webpage Life at GSK | GSK

Find out more about GSK and R&D: Our approach to R&D

Senior Scientist, Upstream Processing

Join us as a Senior Scientist, Upstream Processing and play a key role in advancing scientific research that makes a real difference. You will work closely with diverse teams to design, carry out, and analyze experiments. Your insights will help shape innovative solutions that align with our mission to unite science, technology, and talent to get ahead of disease together. We value curiosity, teamwork, and a hands-on approach to solving important challenges. This role offers meaningful growth and impact as you develop your career in a supportive environment.

We value curious, motivated scientists who take ownership, communicate clearly, and thrive in a collaborative environment. This role offers you a chance to grow your skills, make a meaningful impact, and contribute to GSK’s mission of uniting science, technology, and talent to get ahead of disease together.

This role is located in Upper Merion, PA and requires working on-site. Hybrid or remote work options are not available for this position.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

Leads the manufacture of clinical supply of investigational biopharmaceutical molecules. Specifically: hands-on cGMP large scale cell culture for use in early phase clinical trials
Leads or works on projects and assignments where independent action and a high degree of initiative and knowledge are required for execution or to provide recommendations
Supports the technology transfer process through active participation in ensuring that new processes fit and execute consistently
Troubleshoots problems in the execution of processing activities; proactively assesses options and impact and takes action to rectify or communicate to appropriate decision makers
Identifies process improvement opportunities with impact on safety, compliance, and efficiency/cost
Maintains and performs compliance checks for documentation in logs, media forms, batch records, and electronic systems in accordance with company policy and legal requirements
Strives for Right First Time in the manufacture of investigational material through attention, focus, planning, and adherence to procedural and regulatory expectations

Basic Qualifications We are looking for professionals with these required skills to achieve our goals:

BS, MS, or PhD in Chemical Engineering, Biology, Chemistry, or other engineering or scientific field.
A minimum of 3 years of direct GMP manufacturing experience or upstream processing experience in a biotechnology manufacturing facility or Pilot Plant.

Preferred Qualifications:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

Thorough knowledge of Good Manufacturing Practices (GMP) regulations.
Demonstrates good interpersonal skills and communicates well both verbally and through written communications.
Maintains a professional and productive relationship with area management and co-workers.
Thorough knowledge of routine laboratory/plant equipment and demonstrates high level of technical expertise with working familiarity with several methods, techniques, laboratory procedures and processes.
Possess in-depth knowledge of how to analyze and interpret experimental/process data.

Join us in making a difference in patients’ lives around the world. We value your unique perspective and invite all interested candidates to submit their application.

Skills Data Integrity, Detail-Oriented, Digital Fluency, Emergency Response, Financial Acumen, GxP Regulations, Lean Management, Manufacturing Processes, Problem Solving, Production Management, Project Coordination, Quality Compliance, Regulatory Compliance, Risk Awareness, Site Operations

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK? Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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More about this job

Skills

Clinical trials
Process improvement
Regulatory compliance
Documentation
Media formats
Electronics
Chemical engineering
Good manufacturing practices
Biotechnology
Interpersonal skills
Manage quantitative data
Emergency response
Financial capability
Manufacturing processes
Problem solving
Communicable diseases

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