Jobs in the United States

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Added 27 mins ago
BP
Electrical Engineer (Programming)
Bonneville Power Administration
Spokane, WA · Vancouver, WA
- $99,954 to $140,188 USD / year
GS-11: You must have one year of specialized experience equivalent to the next lower grade (GS-09)
Added 27 mins ago
VH
Registered Nurse - Patient Safety Manager
Veterans Health Administration
Jackson, MS
- $60,112 to $143,910 USD / year
The Registered Nurse - Quality, Safety and Improvement (QSI) Patient Safety Manager (PSM) functions as an advanced clinician and executes position responsibilities that demonstrate…
Added 27 mins ago
VH
Registered Nurse - Informaticist
Veterans Health Administration
Sioux Falls, SD
- $63,446 to $114,610 USD / year
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Added 50 mins ago
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SLCM-N Test Data Program Manager
STRATEGIC SYSTEMS PROGRAMS (SSP)
Washington Navy Yard, DC
- $143,913 to $197,200 USD / year
You will lead technical efforts involving the collection, management, integration, analysis, and interpretation of complex engineering or test data for a major weapons system. | You will…
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CN
OFFICE AUTOMATION ASSISTANT
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Added 53 mins ago
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Added 2 hours ago
Staff Engineering Program Management ( EPM )
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Senior Staff Engineering Program Management ( EPM )
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Senior Principal Engineering Program Management ( EPM )
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…Sites (BaPs) Division is seeking a Senior Principal Engineering Program Manager (EPM) to join our team of qualified and diverse individuals. You will support the Program Manager and Chief…
Added 2 hours ago
Manager, LNP R&D
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Seattle, WA
Serve as the primary technical and organizational leader for LNP R&D and partner with RNA R&D, Operations, Production, Quality, Marketing, Sales, and Program Management.
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Sr. Commercial Scheduler I, Sweeny Gasoline
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Houston, TX
…products such as ethanol. The position will directly report to the Manager, Gulf Coast Clean…
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Dealer Partner Support Specialist - Level 1 (United States)
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Sr. Commercial Scheduler I, Borger
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Added 3 hours ago
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Project Manager II
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Denver, CO
- $75,000 to $112,000 USD / year
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Added 3 hours ago
Information Technology Manager
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Saalex Corporation is seeking multiple Information Technology Manager in Tidewater, VA and San Diego, CA. Saalex Corp., is an Engineering and Information Technology Services company with a…
Added 3 hours ago
Information Technology Manager
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GenScript

Manager, LNP R&D

Seattle, WA, United States

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Job details

Experience: At least 5 years of relevant post-PhD industry or research experience in nucleic acid delivery, drug delivery, lipid nanoparticles, or related technologies.
Posting language: English
Posted: Nov 12, 2026

Original job description

About GenScript

Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation in biotech and healthcare by providing researchers and companies with the building blocks needed to develop groundbreaking treatments and products. Guided by its mission to Make People and Nature Healthier Through Biotechnology, and its role as a well-recognized biotechnology company, GenScript has a team of approximately 6,165 employees and has served more than 200,000 customers across over 100 countries and regions.

Position Summary

GenScript is seeking a highly motivated and experienced scientific leader to lead its Lipid Nanoparticle (LNP) R&D team in Seattle. The successful candidate will bring multidisciplinary expertise in lipid nanoparticles, nucleic acid delivery, formulation development, and RNA therapeutics, together with demonstrated scientific leadership and people-management capability.

This role will lead the development and commercialization of innovative RNA and nucleic acid delivery technologies, with a focus on LNP platforms for mRNA, DNA, small RNAs, and other emerging nucleic acid modalities. The team will translate new delivery technologies, formulations, workflows, and operating capabilities into differentiated GenScript products and services for global research and drug-development customers.

The ideal candidate is both a scientific innovator and a people leader who can convert emerging delivery technologies into scalable, reproducible, and commercially relevant solutions.

Key Responsibilities

Scientific and Technology Leadership

Lead the development of innovative LNP and nucleic acid delivery platforms for mRNA, DNA, small RNAs, and other therapeutic payloads across diverse research and therapeutic applications.
Drive next-generation LNP development, including novel ionizable lipid design and synthesis, formulation optimization, targeted LNPs, extrahepatic delivery, and tissue- or cell-specific delivery strategies.
Establish technology roadmaps and development strategies that create differentiated LNP capabilities, products, and services.
Partner with the RNA R&D team to develop integrated RNA and delivery solutions for vaccines, gene editing, protein replacement, cell engineering, and other emerging applications.
Provide scientific leadership for LNP formulation design, screening, characterization, optimization, and delivery-performance evaluation.
Monitor emerging technologies, scientific publications, competitive platforms, intellectual-property trends, and industry developments in nucleic acid delivery.

Team Leadership and Development

Build, lead, and develop a high-performing LNP R&D team, with responsibility for workforce planning, hiring, resource allocation, budgeting, performance management, and employee development.
Foster a culture of scientific rigor, innovation, accountability, collaboration, transparency, inclusion, and continuous improvement.
Mentor scientists through regular one-on-one meetings, technical guidance, career-development discussions, and timely, constructive feedback.
Allocate resources effectively to achieve project milestones, platform-development objectives, and organizational priorities.

Cross-Functional and Project Leadership

Serve as the primary technical and organizational leader for LNP R&D and partner with RNA R&D, Operations, Production, Quality, Marketing, Sales, and Program Management.
Define project scope, technical strategy, milestones, resource requirements, risks, and timelines for key R&D programs.
Monitor project and team performance and communicate progress, risks, scientific findings, and recommendations to senior leadership through project reviews and presentations.
Review and approve key R&D deliverables, including research reports, experimental protocols, SOPs, technical procedures, production records, presentations, and scientific publications.

Technology Transfer and Commercialization

Lead the translation of new LNP technologies from early-stage R&D into robust, scalable, customer-facing products and services.
Provide technical leadership for formulation scale-up, process optimization, technology transfer, and implementation in Production and Operations.
Work with Production, Quality, and Operations to establish reproducible processes, critical process parameters, analytical requirements, and fit-for-purpose documentation.
Identify opportunities to improve platform performance, operational efficiency, scalability, reproducibility, profitability, and customer value.

Customer and Market Engagement

Serve as a technical expert in customer discussions involving LNP formulation, nucleic acid delivery, troubleshooting, and customized development programs.
Partner with Commercial, Marketing, and Program Management to understand customer needs and translate them into new capabilities and service offerings.
Participate in scientific conferences, technical seminars, and customer engagements to identify emerging trends and unmet needs.
Translate market and customer insights into actionable R&D priorities and technology roadmaps.

Laboratory, Quality, and Safety

Oversee the development, implementation, and continuous improvement of laboratory procedures and technical workflows.
Promote high standards of scientific documentation, experimental reproducibility, data integrity, and laboratory organization.
Ensure compliance with applicable laboratory-safety requirements and GenScript EHS policies, particularly for lipid chemistry, formulation development, and chemical handling.
Collaborate with EHS, Quality, and site leadership to maintain a safe and compliant laboratory environment.
Perform other responsibilities consistent with leading and continuously improving GenScript LNP R&D capabilities.

Required Qualifications

PhD in Pharmaceutical Sciences, Chemistry, Biochemistry, Chemical Engineering, Biomedical Engineering, Bioengineering, or a related discipline.
At least 5 years of relevant post-PhD industry or research experience in nucleic acid delivery, drug delivery, lipid nanoparticles, or related technologies.
At least 2 years of direct people-management experience leading scientific or technical teams, including hiring, coaching, performance management, employee development, and resource planning.
Deep scientific expertise in lipid nanoparticle formulation and nucleic acid delivery, particularly RNA delivery.
Demonstrated hands-on experience in LNP formulation, production, optimization, and analytical characterization.
Strong understanding of lipid-based and/or polymeric nucleic acid delivery technologies.
Experience with particle size/PDI, zeta potential, encapsulation efficiency, RNA concentration, lipid composition, morphology, and stability assessment.
Experience evaluating nucleic acid delivery performance in relevant in vitro and/or in vivo models.
Strong understanding of RNA biology and analytical methods for evaluating RNA quality, delivery, and functional expression.
Experience with relevant molecular and cellular methods, which may include RT-qPCR, ELISA, Western blotting, flow cytometry, fluorescence-based assays, gel electrophoresis, capillary electrophoresis, and RNA-quantification methods.
Demonstrated ability to analyze complex data, identify root causes, design effective experiments, and make data-driven development decisions.
Strong project-management and organizational capabilities, with the ability to manage multiple priorities and development programs.
Excellent scientific writing, presentation, interpersonal, and stakeholder-management skills.
Ability to collaborate effectively and influence across technical and business functions without direct authority.
High standards of integrity, scientific rigor, accountability, teamwork, and professional conduct.

Preferred Qualifications

Experience in novel ionizable lipid design or synthesis, targeted LNPs, extrahepatic delivery, or cell-specific nucleic acid delivery.
Experience developing LNPs for mRNA therapeutics, vaccines, gene editing, in vivo cell engineering, siRNA, or other nucleic acid modalities.
Experience transitioning technologies from early-stage R&D through scale-up, technology transfer, production, or commercial service launch.
Experience in a CRO/CDMO, biotechnology, pharmaceutical, or life-science service organization.
Experience working directly with customers, external collaborators, or commercial teams on technical development programs.
Demonstrated innovation through new technology development, patents, publications, platform development, or successful product/service launches.

Success Profile

The successful candidate will combine deep scientific expertise with strong leadership and execution. They will be comfortable moving between hands-on scientific problem-solving, technology strategy, team development, cross-functional execution, and customer engagement. Most importantly, they will bring scientific curiosity, ownership, creativity, and urgency to building next-generation LNP technologies that strengthen GenScript's global RNA and nucleic acid delivery capabilities.

Perks:

Free colleague meals during shift
Onsite gyms

Compensation:

Salary range: $125,000 – $160,000 total compensation, including bonus, depending on experience and qualifications.

Benefits:

Benefits include medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and company holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.

Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.

Apply on job-boards.greenhouse.io About employer

More about this job

Skills

Leadership
Team leadership
Research
Editing
Budget management
Performance management
Sales
Program management
Presentation skills
Translation
Documentation
Troubleshooting
Customer insight
Process improvement
Regulatory compliance
Handle chemicals
Chemical engineering
Biomedical engineering
Coaching
Pentaho Data Integration
Project management
Stakeholder management
Teamwork
Biotechnology
Problem solving
Team building

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Jobs in the United States