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Added 1 min ago
Software Engineer II
Amentum
Boise, ID
The Software Engineer II will perform full stack development with C# program, ReactJS, MVC, Linq, and rest API development in NET Core platform. This position is US remote teleworking…
Added 1 min ago
IT Software Engineer IV
Idaho Division of Human Resources
Boise, ID
Considerable knowledge of software architecture, systems integration, application design, cloud technologies, development methodologies, testing practices, and modern software engineering…
Added 1 min ago
Senior Systems Engineer
Anduril Industries
Costa Mesa, CA
…re-inventing an existing platform through heavy modification and integration of advanced autonomy, mission systems, and…
Added 10 mins ago
SS
Space Launch Engineer, SSC/SYD 80
Space Systems Command
Kirtland AFB, NM
- $90,479 to $139,871 USD / year
…Force's premier rapid response launch team as a Space Launch Engineer & Program Manager, where your work directly supports the Nation's most critical defense missions. This is your chance…
Added 21 mins ago
SS
Senior Engineer, SSC/SW
Space Systems Command
Chantilly, VA
- $142,488 to $195,200 USD / year
…leadership regarding the strategic continuation, redirection, or integration of major defense systems. Acting as a collaborative bridge across military branches, defense agencies, and…
Added 24 mins ago
NS
ENGINEER/SCIENTIST
Naval Sea Systems Command
Crane, IN
- $125,776 to $192,331 USD / year
…experience must demonstrate the following: as a professional engineer or scientist, overseeing planning and execution of technical engineering or scientific projects involving design,…
Added 29 mins ago
FT
Associate Software Engineer - Full Stack Developer
Franklin Templeton
Baltimore, MD
- $100,400 to $118,200 USD / year
The Enterprise Data, Governance & Integration Platforms Engineering team builds and manages foundational data, API, integration, and application platforms that enable scalable, secure, and…
Added 37 mins ago
Field System Technician
Bechtel Corporation
Millersport, OH
…gas turbines, reciprocating engines, battery energy storage systems (BESS), substations, and associated balance of plant infrastructure. The scope includes major civil, mechanical,…
Added 38 mins ago
SS
General Engineer
Space Systems Command
Peterson AFB, CO
- $129,096 to $197,200 USD / year
…Infrastructure (SFPAE-INF) is seeking a highly motivated and experienced systems engineering leader to join our team to be the Chief Engineer of the SFPAE-INF Capability Trade Council. The…
Added 39 mins ago
GPS Engineer
Applied Materials
Santa Clara, CA · Santa Clara
Provides expert-level technical support for semiconductor mainframes, robotic handling systems, and critical subsystems.
Added 41 mins ago
NS
Supervisory Engineer - Strategic Education Outreach Director
Naval Sea Systems Command
Naval Surface Warfare Center, MD
- $143,913 to $197,200 USD / year
…will ensure STEM Program connectivity across NSWCCD, assist in integration/assessment of existing STEM activities across technical departments/facilities and propose new events for the…
Added 41 mins ago
SS
MISSILE BRANCH SAFETY LEAD
STRATEGIC SYSTEMS PROGRAMS (SSP)
Washington Navy Yard, DC
- $143,913 to $197,200 USD / year
You will be responsible for system engineering, integration and test of the assigned program. | You will review and assess overall progress, and develop solutions for all technical,…
Added 58 mins ago
Senior Data Center Controls Engineer
Google
Reston, VA · Atlanta, GA · Austin, TX · Kirkland, WA · New York, NY · San Francisco, CA · Sunnyvale, CA
Experience with mission critical systems (24x7 and no-fail) and operations (e.g., power generation, data center, refinery, chip fabrication, chemical plant processing, etc.).
Added 58 mins ago
Staff Software Engineer, Accelerators Systems Platforms Software Architect
Google
Sunnyvale, CA
…firmware, Linux kernel drivers, hardware design simulators, integration within Google server and cluster configuration, monitoring and massive distributed systems. We are helping develop…
Added 59 mins ago
Lead MV Electrical Engineer, PE - Power & Infrastructure
Monterra
Remote, United States
We're hiring our first MV Electrical Engineer, who will serve as the technical authority and in-house subject matter expert on medium-voltage power systems. You’ll work closely with our…
Added 1 hour ago
IVA Spacesuit Systems Engineer
Amentum
Houston, TX
We have an exciting opportunity for a IVA Spacesuit Systems Engineer to join the Nexus, a teammate company!
Added 1 hour ago
MD
General Engineer
Missile Defense Agency
Schriever AFB, CO · Redstone Arsenal, AL
- $130,987 to $197,200 USD / year
…The incumbent will be responsible for serving as a General Engineer for The Engineering Directorate supporting Command & Control, Battle Management & Communications…
Added 1 hour ago
AC
BIOLOGICAL SCIENTIST (ENVIRONMENTAL)
Air Combat Command
Luke AFB, AZ
- $93,629 to $121,720 USD / year
…experience at the next lower grade GS-11, or equivalent in other pay systems. Examples of specialized experience includes knowledge of a wide range of complex environmental science duties;…
Added 1 hour ago
UA
Aerospace Engineer
U.S. Army Aviation and Missile Command
Fort Eustis, VA
- $127,646 to $195,190 USD / year
About the Position: Serves as a Aerospace Engineer for the US Army Aviation and Missile Command, Aviation Integration Directorate, located in Fort Eustis, VA.
Added 1 hour ago
IS
Quality Analyst Engineer - Senior
Information Systems
United States
- $120,000 to $135,000 USD / year
· Knowledge of integration testing of third-party systems.
Added 1 hour ago
Field System Technician
Bechtel
Millersport, OH
…gas turbines, reciprocating engines, battery energy storage systems (BESS), substations, and associated balance of plant infrastructure. The scope includes major civil, mechanical,…
Added 1 hour ago
UA
Civil Engineer
U.S. Army Corps of Engineers
Rock Island, IL · New Orleans, LA · Saint Louis, MO · Vicksburg, MS · Memphis, TN · Saint Paul, MN
- $89,508 to $126,859 USD / year
About the Position: Serves as a Journey-Level Navigation/Civil Engineer conducting complex analysis, design, and technical reviews for inland navigation structures and systems, including…
Added 1 hour ago
J
Technical Architect Senior
Jobgether
Remote, United States
- $201,950 USD / year
At least 5 years of professional experience as an Information Systems Architect, Technical Architect, Software Engineer, Enterprise Systems Architect, or in a closely related position.
Added 1 hour ago
CI
Embedded Software Test Automation Engineer
Cintal, Inc.
Chillicothe, IL
- $90,000 to $110,000 USD / year
Develop and validate embedded software for engine control systems.
Added 1 hour ago
NA
INTERDISCIPLINARY ENGINEER
Naval Air Systems Command
San Diego, CA · Patuxent River, MD
- $143,913 to $197,200 USD / year
You will serve as a INTERDISCIPLINARY ENGINEER in the Mission Systems Group, Avionics Engineering Department, Avionics Systems Engineering Division, Tactical Avionics Branch of…

Closed listing

Genentech

Senior Software Engineer - Lab Automation

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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