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Subject Matter Expert I
ARSIEM
Arlington, VA
ARSIEM is looking for a Senior Detection Engineer. The Senior Detection Engineer develops, validates, deploys, and tunes detection logic supporting proactive threat hunting across federal…
Added 1 min ago
Senior DevOps Engineer
TerraPower LLC.
Bellevue, WA
The Senior DevOps Engineer owns the enterprise DevOps toolchain (GitHub Enterprise, Jenkins, Artifactory, and Xray) and is accountable for maturing DevOps practices across the organization.…
Added 2 mins ago
Principal Solution Engineer - Oracle EPM and Hyperion HFM
American Water
Camden, NJ
…our existing EPBCS and Hyperion Financial Management (HFM) systems. The ideal candidate will be responsible for ensuring the stability, performance, and efficiency of financial planning…
Added 2 mins ago
AV Systems Designer/Audio Visual Design Engineer
American Water
Camden, NJ
Leads the detailed engineering of enterprise audiovisual and collaboration systems from discovery and site survey through design development, construction documentation, technical review,…
Added 4 mins ago
R
MES Application & Integration Expert
Roche
Indianapolis, IN
- $85,000 to $157,800 USD / year
We are seeking a proactive and skilled MES Engineer with 4+ years of experience to support, configure, and integrate Manufacturing Execution Systems within our production facility. In this…
Added 5 mins ago
DevOps Engineer
Vailexa
Remote, United States
As a DevOps Engineer supporting Cloud Infrastructure, you will help improve and maintain foundational infrastructure components used across the organization, including:
Added 7 mins ago
Sr. Firmware Engineer II
Samsara
Remote, United States
Samsara (NYSE: IOT) is the pioneer of the Connected Operations™ Cloud, which is a platform that enables organizations that depend on physical operations to harness Internet of Things (IoT)…
Added 7 mins ago
WI
Principal, Software Engineer - Walmart Data Ventures
Walmart Inc.
United States
- $132,000 to $264,000 USD / year
The Principal Software Engineer leads platform engineering efforts by delivering scalable, cloud-native solutions and reusable infrastructure components that support long-term technical…
Added 7 mins ago
WI
Staff, Software Engineer
Walmart Inc.
United States
- $143,000 to $286,000 USD / year
Join Walmart as a Staff Software Engineer to lead the design, development, and deployment of scalable platform capabilities, including infrastructure, tooling, and AI/ML frameworks. This…
Added 8 mins ago
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Senior Mechanical Engineer
Lumafield
San Francisco, CA
- $150,000 to $190,000 USD / year
The Hardware Group is looking for a Senior Mechanical Engineer to help design, prototype, and refine the next generation of our industrial CT scanning systems. You’ll work across…
Added 8 mins ago
BH
Applied AI Engineer
Blossom Health
New York City, NY
- $150,000 to $220,000 USD / year
…clinically-effective mental healthcare. Our AI-native care platform is loved by hundreds of clinicians and thousands of…
Added 8 mins ago
BH
Software Engineer
Blossom Health
New York City, NY
- $150,000 to $220,000 USD / year
…clinically-effective mental healthcare. Our AI-native care platform is loved by hundreds of clinicians and thousands of…
Added 8 mins ago
LA
Senior Optical Test Development Engineer
Lyte AI
Sunnyvale, CA
- $150,000 to $260,000 USD / year
Lyte builds perception systems for Physical AI operating in complex environments. The company combines custom silicon, integrated sensors, and software into a unified platform for robotics,…
Added 9 mins ago
Software Products and Platform Engineering Specialist
Accenture
Saint Louis, MO
A highly capable back-end software engineer with experience designing, building, and operating production systems at scale. You are comfortable owning services through the full software…
Added 9 mins ago
A
Devsecops Engineer
Actalent
Wilmington, MA
- $70 to $100 USD / hour
Job Title: DevSecOps EngineerJob DescriptionThe DevSecOps Engineer will design, implement, and maintain robust security controls across AWS cloud environments that support connected medical…
Added 9 mins ago
A
Golang Software Engineer
Actalent
Raleigh, NC
- $50 to $60 USD / hour
Job Title: Golang Software Engineer (Mid-Expert Platform Engineering)Job DescriptionThis contract role offers an opportunity for a mid-expert level Golang Software Engineer to join a…
Added 9 mins ago
A
Field Service Engineer
Actalent
Racine, WI
- $30 to $55 USD / hour
…focuses on field commissioning and startup of building automation systems at a state-of-the-art data center. You will use advanced Direct Digital Control (DDC) technology to ensure HVAC,…
Added 9 mins ago
A
Field Service Engineer
Actalent
Mount Pleasant, WI
- $30 to $55 USD / hour
…focuses on field commissioning and startup of building automation systems at a state-of-the-art data center. You will use advanced Direct Digital Control (DDC) technology to ensure HVAC,…
Added 10 mins ago
Cybersecurity Analyst
Bertram Capital Management
Remote, United States
…analytics, application development and internal and external platform…
Added 11 mins ago
Software Engineer III, Cloud Infrastructure
MyFitnessPal
Remote, United States
We are looking for a Senior Software Engineer to join the MyFitnessPal Infrastructure team. As a member of the MyFitnessPal Infrastructure team, you’ll have the opportunity to positively…
Added 11 mins ago
SA
System Support Engineer
State Air Resources Board
CA
- $6,513 to $10,537 USD / month
…programs rely extensively on data and web-based information systems. The mission of CARB's Office of Information Services (OIS) is to leverage the most effective information technologies…
Added 11 mins ago
Senior Software Engineer
Tebra
Remote, United States
We are seeking a talented and enthusiastic Senior Front-End Engineer to lead the development of our next-generation Practice Management platform.
Added 13 mins ago
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Senior Full-Stack Engineer, Annotation Platform
Cohere
Remote, United States
- $215,000 to $295,000 CAD / year
We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for…
Added 15 mins ago
Senior Software Engineer, Metadata Platform
Box
Redwood City, CA
As we embark on the mission to deliver a next-generation Metadata Platform, we're looking for a Senior Engineer to join us and play a pivotal role. You'll have the opportunity to work with…
Added 15 mins ago
A
Strategy and Program Manager
Adyen
NY
- $145,000 to $180,000 USD / year
A systems thinker who looks beyond the immediate task to platform dependencies and technical trade-offs, and who sees how a decision in one area ripples across the customer journey.

Closed listing

Genentech

Senior Software Engineer - Lab Automation

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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