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Senior Applications Engineer
Datacolor
Lawrenceville, NJ
The Senior Applications Engineer provides technical and color-management support, diagnoses software issues, and assists customers via phone, email, and remote access. The role requires 2–6…
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AT
Network Infrastructure Engineer II
Akamai Technologies, Inc.
Juneau, AK
- $83,200 to $149,800 USD / year
As a Network Infrastructure Engineer II, you will oversee operations in our global data centers. You will monitor and maintain our data centers, networks, and servers worldwide. You will…
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Mainframe Technical Engineer
Highmark Health
Juneau, AK
…COUPLING FACILITY technical ecosystem including infrastructure, systems, networks, applications, integrations, etc. They will work closely with other technical professionals, analysts, and…
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Civil Engineer - UMIAQ Design
UIC Government Services and the Bowhead Family of Companies
Anchorage, AK
UMIAQ Design is seeking a registered Civil Engineer to support a diverse portfolio of challenging projects throughout both rural and urban Alaska. With several recent large project awards…
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Software Engineer, Infrastructure - Central Growth
Meta
Juneau, AK
Software Engineer, Infrastructure - Central Growth Responsibilities:
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Software Engineer II
Amentum
Juneau, AK
The Software Engineer II will perform full stack development with C# program, ReactJS, MVC, Linq, and rest API development in NET Core platform. This position is US remote teleworking…
Added 1 min ago
FT
Associate Software Engineer - Full Stack Developer
Franklin Templeton
Baltimore, MD
- $100,400 to $118,200 USD / year
…and reusable platform capabilities using AWS, Azure, modern software engineering practices, CI/CD automation, and AI-assisted development. We partner with application development, data,…
Added 1 min ago
IC
Lab Engineer
Intel Corporation
OR
- $85,950 to $166,060 USD / year
Intel Foundry is seeking a detail-oriented and highly motivated Lab Engineer to join our Advanced Design Lab team. In this role, you will support the development, operation, and…
Added 10 mins ago
AO
Senior Construction Inspector
Architect of the Capitol
Washington, DC
- $102,415 to $133,142 USD / year
This position is located in the Architect of the Capitol, Office of the Chief Engineer, Construction Management Division, Construction Management Branch. The selectee will be responsible…
Added 13 mins ago
SS
MISSILE BRANCH SAFETY LEAD
STRATEGIC SYSTEMS PROGRAMS (SSP)
Washington Navy Yard, DC
- $143,913 to $197,200 USD / year
…demonstrate professional engineering experience directing the full systems engineering life cycle from design through production for integrated strategic weapons systems, experimental…
Added 18 mins ago
VP of Engineering
Jobgether
Remote, United States
…development of the first donation management platform for healthcare systems, replacing manual, email-based workflows. Build and maintain products serving healthcare providers, health…
Added 24 mins ago
Data Center Technician, 3PDC
Google
Phoenix, AZ
Experience with performing component-level repairs and troubleshooting on IT equipment or in a similar role (e.g. Systems Administration, Network Deployment Engineer, Help Desk Technician,…
Added 24 mins ago
Staff Optical Validation Engineer, Google Cloud
Google
Sunnyvale, CA
hardware and software technologies that power all of Google's services. Our computational challenges are complex and unique, enabled by cutting-edge custom hardware designed and made…
Added 24 mins ago
Senior Staff Software Engineer, AI/ML, Multimodal Rich Features
Google
Mountain View, CA
Google's software engineers develop the next-generation technologies that change how billions of users connect, explore, and interact with information and one another. Our products need to…
Added 28 mins ago
Infrastructure Specialist
Kyndryl, Inc.
Remote, United States
6 years expertise within specific technology domain areas (e.g., software development, cloud computing, systems engineering, infrastructure, security, networking, data & analytics)
Added 30 mins ago
Site Reliability Manager, Android SRE
Google
San Francisco, CA
Proficiency in algorithms, data structures, complexity analysis and software design or expertise in Unix/Linux systems, IP networking, performance and application issues.
Added 31 mins ago
Senior Software Engineering Manager, AI/ML
Google
San Francisco, CA
Like Google's own ambitions, the work of a Software Engineer goes beyond just Search. Software Engineering Managers have not only the technical expertise to take on and provide technical…
Added 31 mins ago
Staff Software Engineer, Site Reliability Engineering, Raxium
Google
Fremont, CA
Site Reliability Engineering (SRE) is what you get when you treat operations as if it’s a software problem. Our mission is to progress, protect, and provide for the software and systems…
Added 31 mins ago
Senior Staff Hardware Engineer Technical Lead, AI Infrastructure
Google
Sunnyvale, CA
This team is looking for engineers with exposure to fully integrated AI infrastructure systems, from Hardware to Software design and workload management. In this role, you will have…
Added 31 mins ago
Senior Data Center Controls Engineer
Google
Reston, VA · Atlanta, GA · Austin, TX · Kirkland, WA · New York, NY · San Francisco, CA · Sunnyvale, CA
Experience designing, configuring, programming, installing and troubleshooting BMS and Electrical SCADA systems application specific controllers and software such as Ignition and Factory…
Added 31 mins ago
Staff Software Engineer, Agentic, Optimization, Recursive Self-Improvement
Google
Mountain View, CA
Google's software engineers develop the next-generation technologies that change how billions of users connect, explore, and interact with information and one another. Our products need to…
Added 31 mins ago
Staff Software Engineer, Accelerators Systems Platforms Software Architect
Google
Sunnyvale, CA
Google's software engineers develop the next-generation technologies that change how billions of users connect, explore, and interact with information and one another. Our products need to…
Added 31 mins ago
Lead MV Electrical Engineer, PE - Power & Infrastructure
Monterra
Remote, United States
We're hiring our first MV Electrical Engineer, who will serve as the technical authority and in-house subject matter expert on medium-voltage power systems. You’ll work closely with our…
Added 33 mins ago
IVA Spacesuit Systems Engineer
Amentum
Houston, TX
We have an exciting opportunity for a IVA Spacesuit Systems Engineer to join the Nexus, a teammate company!
Added 1 hour ago
MD
General Engineer
Missile Defense Agency
Schriever AFB, CO · Redstone Arsenal, AL
- $130,987 to $197,200 USD / year
…The incumbent will be responsible for serving as a General Engineer for The Engineering Directorate supporting Command & Control, Battle Management & Communications…

Closed listing

Genentech

Senior Software Engineer - Lab Automation

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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