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Added 5 mins ago
Sr. DevOps Engineer
Forta Solutions, LLC
Denver, CO
Forta Solutions is seeking a Senior DevOps Engineer to design, automate, secure, and maintain our AWS infrastructure and software delivery systems. This role will improve platform…
Added 15 mins ago
Technical Services Engineer
Simr
Remote, United States
Collaborate closely with customers and senior engineers to understand technical requirements, assist in tailoring deployments, and customize platform deployments to meet their specific…
Added 25 mins ago
Senior Firmware Engineer, Embedded Platform
Firestorm
United States
Firestorm Labs is seeking an experienced and driven Firmware Engineer who has a specialized focus in embedded platforms. In this role, you will support the development, integration, and…
Added 29 mins ago
Senior Frontend Engineer
TeamSnap
Remote, United States
TeamSnap is seeking a Senior Frontend Engineer interested in working across the stack to join our fully distributed engineering team to help us continue our impressive growth from 2+…
Added 38 mins ago
Regional Maintenance Manager
Amazon.com Services LLC
Kearny, NJ · Jessup, PA
Join our Reliability & Maintenance Engineering team and help keep Amazon's operations running smoothly across hundreds of countries. You'll work on maintaining and improving the robotics…
Added 39 mins ago
TA
Senior Software Engineer (Platform Engineering)-Remote, USA
Tempus AI, Inc.
Remote, United States
- $130,000 to $150,000 USD / year
The Senior Software Engineer is a hands-on technical leader responsible for architecting and delivering the Java-based services at the core of Ambry's platform modernization. This role…
Added 51 mins ago
Advanced Systems Engineer - Aircraft Data Networks
Aerospace
Phoenix, AZ
Advanced Systems Engineer – Aircraft Data Networks
Added 53 mins ago
Senior Software Engineer - Cloud Enablement
Garmin International, Inc.
Olathe, KS
We are seeking a full-time Senior Software Engineer to join our Cloud Enablement team in Olathe, KS - This is a brand-new group helping Software Engineering teams across Garmin to build and…
Added 1 hour ago
PI
Senior Principal AI Research Engineer
Pfizer Inc
WA · CA · MA · CT · NY
- $139,100 to $231,900 USD / year
As a Senior Principal AI Research Engineer, you will build the machine learning systems that transform innovative models into secure, reliable, and scalable capabilities for scientists…
Added 1 hour ago
PI
Senior AI Research Engineer
Pfizer Inc
WA · CA · MA · CT · NY
- $106,000 to $176,600 USD / year
As a Senior AI Research Engineer, you will build the machine learning systems that transform innovative models into secure, reliable, and scalable capabilities for scientists across Pfizer.
Added 1 hour ago
AI Engineer 4 (AI Foundations: World Model, RL, Causal Inference, Sequential Data)
Capital One
McLean, VA · Cambridge, MA · San Jose, CA · NY
Define and maintain service-level objectives (SLOs) for AI reliability, including latency, uptime, and model performance drift
Added 1 hour ago
Quality Assurance/Quality Control Manager
LEIDOS, INC.
San Diego, CA
…operational efficiency, reduce quality risks, and strengthen process reliability without compromising military…
Added 1 hour ago
Embedded Software Test Engineer
Dynetics, Inc
Huntsville, AL
The Embedded Software Test Engineer will support testing and validation activities for embedded systems within complex technical environments. The ideal candidate will possess extensive…
Added 1 hour ago
Embedded Software Test Engineer
Dynetics, Inc
Huntsville, AL
The Embedded Software Test Engineer will support testing and validation activities for embedded systems within complex technical environments. The ideal candidate will possess extensive…
Added 1 hour ago
OS
Systems Engineer
OC Sports & Entertainment, LLC
United States
- $128,000 to $145,000 USD / year
Reporting to the Manager of Systems Engineering, the Systems Engineer works closely with senior infrastructure personnel, IT leadership, and cross-functional technical teams to support…
Added 1 hour ago
Senior CS Technical Support Engineer
Cymer, LLC. (US01)
San Diego, CA
As a Senior CS Technical Support Engineer, you will deliver technical support for Cymer laser products in Integrator and Chipmaker Operations. The Cymer Global Support Center (GSC) provides…
Added 1 hour ago
E
Principal Embedded Software Engineer
Emerson
Shakopee, MN
- $150,000 to $200,000 USD / year
Join our Liquid Analysis team in Shakopee, MN, as a Principal Embedded Software Engineer, where you'll focus primarily on new product development while also supporting sustaining…
Added 1 hour ago
F
Senior Software Engineer, Stablecoin Payments
Flex
Remote, United States
- $170,000 to $280,000 USD / year
…fintech engineering: payments, onboarding, compliance, and reliability. If you’ve built that kind of system and want to learn the crypto side, we want to…
Added 2 hours ago
Hardware Design Engineer Intern
Emerson
Round Rock, TX
…devices behind DeltaV , our flagship distributed process control system used by leading chemical, life sciences, and energy companies around the world. Working alongside experienced…
Added 2 hours ago
Senior Software Engineer
Raydar
New York, NY
…backend services and user-facing features, with a strong focus on reliability and auditability. A background in backend or infrastructure engineering and prior experience shipping AI agents…
Added 2 hours ago
Product Manager
NAB NorthAB, LLC
Remote, United States
North is seeking a highly detail-oriented and technically proficient Senior Product Manager to drive the execution of our product roadmap and oversee the delivery of innovative, high-impact…
Added 2 hours ago
Senior Supplier Quality Engineer - Sentry
Anduril Industries
Irvine, CA
As a Senior Supplier Quality Engineer on the Sentry products team, you will work inside and outside the organization to define, develop, and execute processes that deliver high quality and…
Added 2 hours ago
Senior Flight Test Engineer, Omen
Anduril Industries
Costa Mesa, CA
As a Senior UAS Flight Test Engineer you will plan, execute and report on developmental and operational flight Test & Evaluation (T&E) activities. You will work alongside a team of…
Added 2 hours ago
SCADA Engineer
Robert Half
Houston, TX
Description We are looking for a SCADA Engineer to lead the engineering, performance, and long-term reliability of real-time control systems that support distributed energy and microgrid…
Added 2 hours ago
Field Service Engineer Drives and Automation
GE Vernova
Houston, TX
Under the direction of a senior engineer performs a wide range of technical tasks to ensure the technical integrity and proper installation and commissioning of GE drive systems

Closed listing

Genentech

Senior Software Engineer - Lab Automation

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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