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Added 1 min ago
Radar Engineer
SAIC
Denver, CO
SAIC is seeking a Radar Engineer to join the National Security and Space Sector (NSS). You would work on a joint Intelligence Community (IC) and Department of Defense (DoD) crown jewel…
Added 5 mins ago
(Senior) Applications Engineer
Vertical Semiconductor
Somerville, MA
We’re hiring a (Senior) Applications Engineer to help customers design in next-generation vertical GaN power devices (100 V – 2300 V) and turn device performance into system-level wins.…
Added 17 mins ago
Sr. GNC Engineer / Modeling & Simulation
Mavensoft Technologies, LLC.
Chandler, AZ
Leading the design, development, implementation, verification, and test of high quality software and simulation toolchains; owning the development and maintenance of six degree of freedom…
Added 26 mins ago
Staff Device Development Engineer
Samsung Austin Semiconductor, LLC.
Austin, TX
SAS is looking for a highly driven and technically accomplished engineer to lead critical initiatives within the New Technology Bridge Device Integration team. This is a high-impact role…
Added 29 mins ago
Staff Systems Engineer - I&T
Northrop Grumman
Baltimore, MD
…results and prepares comprehensive reports; Use modeling and simulation tools to expedite testing of individual units before all system components are available and for troubleshooting and…
Added 29 mins ago
Principal / Sr. Principal Systems Engineer – I&T
Northrop Grumman
Baltimore, MD
…results and prepares comprehensive reports; Use modeling and simulation tools to expedite testing of individual units before all system components are available and for troubleshooting and…
Added 40 mins ago
Modeling and Simulation Engineer
IRC Trane Technologies Company LLC
Tyler, TX · Pueblo, CO · La Crosse, WI · Clarksville, TN
Join Trane Technologies as a Modeling and Simulation Engineer and be at the forefront of innovation in HVAC technology. In this role, you will support HVAC product development through…
Added 46 mins ago
GNC Engineer - Modeling, Simulation
Mavensoft Technologies, LLC.
Chandler, AZ
Leading the design, development, implementation, verification, and test of high‐quality software and simulation toolchains; owning the development and maintenance of six‐degree‐of‐freedom…
Added 1 hour ago
Test & Validation Engineer
Lafayette, IN
The Test & Validation Engineer focuses on Gas/DF HIL Software Validation. The scope of this role will include configuring HIL hardware, integrating engine plant models, and validating NPI,…
Added 1 hour ago
Cellular RF System Architect
Apple
San Diego, CA · Sunnyvale, CA
We are looking for a motivated and dedicated engineer to join our team and contribute to our Cellular RF architectures. In this role, you will be at the center of RF innovation, helping to…
Added 1 hour ago
Engineer Senior Principal III – RF
BAE Systems
Westminster, CO
Simulate circuit and system performance using analytical software such as AWR Microwave Office, VSS, Agilent ADS, SystemVue, and MATLAB.
Added 2 hours ago
Sr. Power Electronics Engineer - High Voltage, Satellites (Starlink)
SpaceX
Redmond, WA
…the satellites – they must be cost effective, capable of high performance in all weather conditions, and reliable over long periods of time. The traveling wave tube amplifier (TWTA) team is…
Added 2 hours ago
Systems Engineer III
Qualis LLC
Colorado Springs, CO
Qualis LLc is seeking a Systems Engineer III to support a growing portfolio of software products that focus on missile defense, space, and intelligence and will support various modeling,…
Added 2 hours ago
Senior Digital Design Verification Engineer
Renesas Electronics
Austin, TX
Renesas is seeking a Senior Digital Design Verification Engineer to join our team developing complex power management SoCs. These products integrate digital control, telemetry, fault…
Added 2 hours ago
Systems Engineer II
RTX
United States
Modeling and Simulation: Develop and execute models to predict system performance and support verification and validation.
Added 2 hours ago
Electrical Engineer 1 (Onsite)
RTX
United States
The Rockford, IL Power and Controls division is looking for an entry level Electrical Engineer 1. This role is onsite, in Rockford, IL. This role may be eligible for relocation.
Added 2 hours ago
Scrum Master – Senior Software Engineer
RTX
United States
…looking for a Software Scrum Master (SM) – Senior Software Engineer for the AN/TPY-2 radar program Orcas agile software team. The Orcas team provides subject matter expertise for concept…
Added 2 hours ago
Scrum Master –Software Engineer II
RTX
United States
…Raytheon is looking for a Software Scrum Master (SM) – Software Engineer II for the AN/TPY-2 radar program Orcas agile software team. The Orcas team provides subject matter expertise for…
Added 2 hours ago
Senior Software Engineer - Modeling (Onsite)
RTX
United States
Design and maintain aerospace modeling and simulation systems to support complex engineering projects.
Added 2 hours ago
Software Engineer II - DevOps / Infrastructure (Onsite)
RTX
United States
Take ownership of the program’s CI/CD pipeline, optimizing code integration and delivery of the simulation environment.
Added 2 hours ago
Senior Software Engineer - Agile Product Owner (Onsite)
RTX
United States
Senior Software Engineer - Agile Product Owner - Flight & Mission Simulation (Onsite)
Added 2 hours ago
T
Infrastructure Engineer
TEKsystems
Reston, VA
- $70 to $127 USD / hour
…and cloud trust brokers is degraded or entirely severed. The engineer will establish resilient Policy Enforcement Points (PEP) and decentralized Policy Decision Points (PDP), architect…
Added 2 hours ago
Sr. RF/Microwave Engineer, Satellites (Starlink)
SpaceX
Redmond, WA
…multidisciplinary team focused on developing all elements of new high performance wireless digital communication systems from antenna to protocol level. You will be responsible for the…
Added 2 hours ago
Power Electronics Engineer - High Voltage (Starlink)
SpaceX
Redmond, WA
…the satellites – they must be cost effective, capable of high performance in all weather conditions, and reliable over long periods of time. The traveling wave tube amplifier (TWTA) team is…
Added 2 hours ago
ID&C Enterprise Project Engineer
BNH
Arnold AFB, TN
Beyond New Horizons, LLC (BNH) has an exciting opportunity for an ID&C Enterprise Project Engineer, supporting Test Operations and Sustainment II (TOS II) at Arnold Air Force Base,…

Closed listing

Genentech

Senior Software Engineer - Lab Automation

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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