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Added 6 mins ago
Data Systems AI / ML Engineer
Oak Ridge National Laboratory
Oak Ridge, TN
The Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) is seeking a Data Systems AI/ML Engineer for its Earth Sciences Informatics portfolio. In this role, you…
Added 18 mins ago
Software Engineer, Distributed Compute
Base Power Company
Austin, TX
…across thousands of physical devices deployed in homes and grid infrastructure. We're looking for a Software Engineer to design, build, and maintain the software systems that run on…
Added 31 mins ago
Consulting Architect - Search
Elastic
United States
Acting as a trusted technical advisor, you will work with enterprises to improve application performance, infrastructure visibility, and end-user experience, while also improving their…
Added 35 mins ago
Network Engineer
Paragon Cyber Solutions
Colorado Springs, CO
We are seeking a Network Engineer to join a bright, talented, and dedicated team working on critical infrastructure and security-focused environments. In this role, you will help design,…
Added 35 mins ago
Oracle System Engineer
Paragon Cyber Solutions
Tampa, FL
…those ready for an exciting and dynamic career as a System Engineer (Solaris / Oracle) while supporting critical global…
Added 35 mins ago
Theater Engineer
Paragon Cyber Solutions
Colorado Springs, CO
The Theater Engineer is responsible for supporting the Shared Early Warning System (SEWS) global infrastructure and communications architecture across U.S. Combatant Commands and allied…
Added 36 mins ago
G
Software Engineer, Design
Garage
New York City, NY
- $150,000 to $250,000 USD / year
…expensive, specialized, and difficult to move. We’re building the infrastructure that powers the procurement and disposition of assets across America’s essential industries, automating…
Added 36 mins ago
G
Software Engineer, Growth
Garage
New York City, NY
- $150,000 to $250,000 USD / year
…specialty assets across the country. This involves owning the data infrastructure, internal tools, and AI-powered workflows that fill our…
Added 39 mins ago
Lead Engineer I, System and Infrastructure Administrator (Re
KPMG LLP
SALT LAKE CITY, UT
Added 51 mins ago
Software Engineer, Backend - Factory Software
Base Power Company
Austin, TX
As a software engineer on the Factory Software team, you will be responsible for building the tools we use to purchase, move, manufacture, and deliver batteries to hundreds of thousands of…
Added 52 mins ago
Delivery Management Engineer III
Deloitte
Kansas City, MO
Delivery Management Engineer III- AI & Engineering
Added 52 mins ago
Delivery Management Engineer III
Deloitte
Saint Louis, MO
Delivery Management Engineer III- AI & Engineering
Added 58 mins ago
IT Projects Engineer
Charles IT
Chesapeake, VA
Due to continued growth, we’re looking to add an IT Projects Engineer to our Projects Team. In this role, you'll play a key part in delivering successful client outcomes by leading…
Added 1 hour ago
SAS Data Engineer- Linux
Cesna Recruitment
Austin, TX
- Ensure that Impala, NetApp, HPC, Kubernetes, Greenplum, and GPU storage solutions are fully integrated and compatible with the overall IT infrastructure.
Added 1 hour ago
Linux Engineer
Cesna Recruitment
Austin, TX
- Ensure that Impala, NetApp, HPC, Kubernetes, Greenplum, and GPU storage solutions are fully integrated and compatible with the overall IT infrastructure.
Added 1 hour ago
Software Engineer, Backend - Member Software
Base Power Company
Austin, TX
…pipeline and help us understand what converts. You will build the infrastructure behind experimentation, partner integrations, lead ingestion, attribution, and workflows across direct…
Added 1 hour ago
Systems Engineer
Celtic Bank
Remote, United States
Celtic Bank is seeking a Systems Patch Engineer to manage and optimize our enterprise patch management program. This role focuses on operating system and third-party application patching…
Added 1 hour ago
A
Principal Software Engineering - Reliability and FinOps Engineer
AT&T
Bothell, WA
- $155,400 to $261,100 USD / year
Our organization brings together reliability engineering, FinOps and infrastructure optimization, AI and automation enablement, and customer-centric business intelligence. We build reusable…
Added 1 hour ago
SSL Production Lab Engineer, Space Simulation Lab
Amazon
REDMOND, WA
As a Lab Engineer, you will support test, readiness, and operation of SSL test systems infrastructure. You will work closely with cross-functional engineering teams to translate test needs…
Added 1 hour ago
Software Development Engineer, Fees Tech
Amazon
Seattle, WA
…classification to seller-facing AI surfaces and the agentic infrastructure beneath them. If you are the kind of engineer who wants to see the direct impact of what you ship, you will see it…
Added 1 hour ago
Electrical Design Engineer
CEL - Critical Power
Williamsburg, VA
…at the center of the AI, hyperscale data center and critical infrastructure ecosystem. An Irish-based manufacturer, distributor and exporter of electrical switchgear, controls and related…
Added 1 hour ago
C-
Electrical Engineer - Power Distribution
CEL - Critical Power
Williamsburg, VA
- $100,000 to $120,000 USD / year
…at the center of the AI, hyperscale data center and critical infrastructure ecosystem. An Irish-based manufacturer, distributor and exporter of electrical switchgear, controls and related…
Added 1 hour ago
Senior Project Manager
CEL - Critical Power
Wilmington, VA
10+ years of experience in project management within industrial, engineering, manufacturing, construction, infrastructure, or engineered product environments.
Added 2 hours ago
Network Development Engineer II , ALG Software and Network Integration and Test
Amazon
NORTHRIDGE, CA
We're looking for a Network Development Engineer who can design, build, and operate network infrastructure across data center and engineering environments. You'll own architectures that…
Added 2 hours ago
Field Systems Engineer - Military Health IT (DDIL)
Rackner
Remote, United States
Field Systems Engineer - Military Health IT (DDIL)

Closed listing

Genentech

Senior Software Engineer - Lab Automation

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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