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Added 2 mins ago
GA
Director, Architecture and Data
GE Aerospace
Asheville, NC · Wilmington, NC
- $152,000 to $202,000 USD / year
Supervise the Data Fabric engineers (Sr Staff TPM–Data, Principal Data & Information Architect, Sr Staff Data Engineer, Staff Data Engineer) in a matrixed arrangement, keeping their written…
Added 2 mins ago
CMC Mechanical Analysis Lead Engineer
GE Aerospace
Asheville, NC · Wilmington, NC
The Lead Engineer will be responsible for supporting and leading mechanical analysis projects for CMC hot section hardware and/or interfacing metallic components with specific focus on…
Added 2 mins ago
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GCP data Engineer
Cognizant
Raleigh, NC
- $100,000 to $120,000 USD / year
Cognizant is seeking an experienced Knowledge Graph Data Engineer to build and operate the connectivity, profiling, and graph/search foundation that powers enterprise ontology and knowledge…
Added 2 mins ago
AT
Senior Network Engineer - DDoS
Akamai Technologies, Inc.
Raleigh, NC
- $112,500 to $202,500 USD / year
As a Senior Network Engineer, you will lead efforts in designing, implementing, and automating Akamai's global network infrastructure. You will address complex issues in routing, data…
Added 2 mins ago
Senior AI Forward Deployed Engineer (FDE)
CGI Technologies and Solutions, Inc.
Raleigh, NC
We CGI is seeking an experienced Senior AI Forward Deployed Engineer, candidate will get an opportunity to work with a highly skilled team on the latest technologies. It helps the candidate…
Added 2 mins ago
Senior Manager, Knowledge & Context Architecture
Teradata
Raleigh, NC
Our mission is to design the knowledge an enterprise runs on, engineer the context its AI agents need, and prove that context can be trusted. This helps make Teradata's vision for an…
Added 2 mins ago
Data Strategy & Governance -Director
PwC
Raleigh, NC · Greensboro, NC · Charlotte, NC
What You Must Have
Added 2 mins ago
Sales Representative I , Spine -Charlotte, NC
Medtronic
Charlotte, NC
Must Have: Minimum Requirements · **Must have a valid driver's license and active vehicle insurance policy
Added 3 mins ago
Agentic AI Engineer – Workflow Orchestration & Prompt Engineer
ManpowerGroup
Charlotte, NC
…reliability. This individual translates complex or ambiguous requirements into structured, multi-step workflows that coordinate prompts, tools, context, data, and agent interactions. The…
Added 3 mins ago
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AI Engineer
ManpowerGroup
Charlotte, NC
- $70 to $80 USD / hour
Our client is seeking a AI Engineer to join their team. As a AI Engineer, you will be part of the engineering organization supporting customer-facing delivery. The ideal candidate will have…
Added 3 mins ago
Lead Specialty Software Engineer
Wells Fargo
CHARLOTTE, NC
Wells Fargo is seeking a Cyber AI Lead Software Specialty Engineer to spearhead the design, development, and deployment of next-generation agentic AI systems within the cybersecurity space.…
Added 3 mins ago
Cloud Security Program and Transformation Leader - Technology Director
Wells Fargo
CHARLOTTE, NC
Skill in business analysis and business enablement to translate business needs into actionable technology requirements and outcomes
Added 3 mins ago
Engineer II, Google Cloud
PwC
Charlotte, NC · Raleigh, NC · Greensboro, NC
What You Must Have
Added 3 mins ago
Senior information Security Engineer
Wells Fargo
CHARLOTTE, NC
Wells Fargo is seeking a Senior Information Security Engineer in Technology as part of Cybersecurity. Learn more about the career areas and lines of business at wellsfargojobs.com
Added 3 mins ago
EP Mapping Specialist CAS - Charlotte, NC
Medtronic
Charlotte, NC
Must have a valid driver's license and active vehicle insurance policy
Added 3 mins ago
Lead AI Engineer
Wells Fargo
CHARLOTTE, NC
Wells Fargo is seeking a Lead AI Engineer in Technology as part of Commercial and Corporate & Investment Banking Technology (CCIBT). The primary focus of this group will be to accelerate AI…
Added 3 mins ago
Applied AI Health System Engineer [Health Services-Provider] – Senior Manager
PwC
Charlotte, NC · Greensboro, NC · Raleigh, NC
What You Must Have
Added 3 mins ago
Senior AI Agent Engineer (Autonomous Remediation & DevSecOps / FTE)
NTT America, Inc.
Charlotte, NC
We are currently seeking a Senior AI Agent Engineer (Autonomous Remediation & DevSecOps / FTE) to join our team in Charlotte , North Carolina (US-NC) , United States (US) .
Added 3 mins ago
Senior Manager, Agentic AI Engineer
PwC
Charlotte, NC · Raleigh, NC · Greensboro, NC
What You Must Have
Added 3 mins ago
Senior Associate, Azure AI Engineer
PwC
Raleigh, NC · Charlotte, NC · Greensboro, NC
What You Must Have
Added 3 mins ago
Google Cloud Engineer - Senior Associate
PwC
Raleigh, NC · Charlotte, NC · Greensboro, NC
What You Must Have
Added 3 mins ago
ND
Infrastructure Engineer (SQL Server & Windows)
NTT Data Americas, Inc.
Charlotte, NC
- $55 to $65 USD / hour
NTT DATA's Client is seeking an experienced, hands-on SQL Server and Windows Infrastructure Engineer to support the build-out and configuration of new application environments. The…
Added 3 mins ago
Confluent - Staff Software Engineer - Stream Governance
IBM
RESEARCH TRIANGLE PARK, NC
As a Staff Software Engineer at Confluent, you will take ownership of critical backend systems in Stream Governance products that underpin our data streaming platform. You’ll lead the…
Added 3 mins ago
EG
Front End React Engineer
Eliassen Group
Raleigh, NC
- $80 to $90 USD / hour
Our client seeks an experienced Front End React Engineer to join a small, focused team building features across three SaaS products in consumer goods retail. Global brands and retailers…
Added 3 mins ago
EG
Senior Systems Administrator / Infrastructure Engineer
Eliassen Group
Raleigh, NC
- $65 to $75 USD / hour
Our client seeks a senior-level Systems Administrator or Infrastructure Engineer to administer Linux and Windows Server environments, manage AWS services, and drive automation and…

Closed listing

Senior Software Engineer - Lab Automation

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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Jobs in the United States