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Added 13 mins ago
TT
Founding Senior Engineer
True Talent Solutions Partners
New York, NY
- $175,000 to $225,000 USD / year
Join an early-stage AI company building growth automation for consumer brands. As a hands-on player-coach, you will shape the engineering foundations and help deliver systems that improve…
Added 27 mins ago
Principal Engineer, Threat Hunting
T-Mobile USA, Inc.
Bellevue, WA · Overland Park, KS · Frisco, TX
The Principal Engineer, Threat Hunter is critical to protecting T-Mobile’s digital assets, serving on the Continuous Hunting and Offensive Specialists (CHAOS) team, T-Mobile’s elite…
Added 30 mins ago
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Electrical Engineer
Subsense
Mountain View, CA
- $90,000 to $110,000 USD / year
This role offers an opportunity for an early-career engineer to gain hands-on experience across electrical engineering, biomedical instrumentation, and multidisciplinary system development.…
Added 32 mins ago
Marketing Lead
Flint
San Francisco, CA
- Experience with marketing automation or sales enablement tools (HubSpot, Notion, etc.).
Added 37 mins ago
Application Support Technical Team Lead
Kastel Staffing
Sandy Springs, GA
Experience as an Application Support Engineer supporting, maintaining, and enhancing enterprise applications.
Added 45 mins ago
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Robotics Software Engineer
True Talent Solutions Partners
Watertown, MA
- $130,000 to $180,000 USD / year
- One to three years of software engineering experience in robotics, automation, or embedded systems.
Added 46 mins ago
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Sr. Al Solution Engineer
Kentro
UNAVAILABLE
- $101,000 to $140,000 USD / year
Kentro is hiring for a Sr. AI Solution Engineer to support secure cloud data and applied AI initiatives for government customers. You will build governed data pipelines, automate cloud and…
Added 58 mins ago
PowerApps Engineer
Robert Half
Fort Lauderdale, FL
We are looking for an experienced PowerApps Engineer to support enterprise Power Platform initiatives for a client in Fort Lauderdale, Florida. This Long-term Contract position focuses on…
Added 1 hour ago
Senior Member of Technical Staff, Product Engineering
Pallet
NY · San Francisco, CA
…(ex-Google), Nilkanth (ex-founder, ex-DoorDash), and Vidhur (lead engineer on Document AI at Scale) to shape the future of logistics AI - from how it's built to how it's deployed in the…
Added 1 hour ago
Senior Member of Technical Staff, Product Engineering
Pallet
San Francisco, CA · NY
…(ex-Google), Nilkanth (ex-founder, ex-DoorDash), and Vidhur (lead engineer on Document AI at Scale) to shape the future of logistics AI - from how it's built to how it's deployed in the…
Added 1 hour ago
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Senior System Engineer - Odessa, TX
Oracle
Odessa, TX
- $35.63 to $71.3 USD / hour
The Systems Engineer will play a key role in maintaining, upgrading, and evolving the organization’s core infrastructure to ensure stability, performance, and security across enterprise…
Added 1 hour ago
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Principal Core Infrastructure Engineer
Oracle
Austin, TX
- $114,600 to $234,600 USD / year
Oracle Cloud Infrastructure (OCI) is hiring a Principal Core Infrastructure Engineer to join the Next Gen Network Observability team. Help build cloud-scale intelligence systems that enable…
Added 1 hour ago
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Core Infrastructure Engineer 2
Oracle
Nashville, TN
- $70,000 to $166,100 USD / year
…replication and synchronization. Assists with on-call rotations, uses automation/IaC scripts to troubleshoot, and follows change, security, and compliance procedures (encryption, access…
Added 1 hour ago
Infrastructure Engineer, Enterprise AI
Wonder Group, INC
Remote, United States
Wonder’s Enterprise Technology team is hiring an Infrastructure Engineer to establish and scale the hosting, deployment, and integration foundations that support builders of all technical…
Added 1 hour ago
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Principal Core Infrastructure Engineer
Oracle
Nashville, TN · Seattle, WA · Santa Clara, CA
- $114,600 to $234,600 USD / year
…remediation, maintains compliance documentation, and develops IaC and automation that enable safe patching, updates, and rollbacks within change‑management…
Added 2 hours ago
Offensive Security AI Engineer
Micron Technology
Boise
The Offensive Security AI Engineer will plan and implement adversary-informed security testing across Micron's technology environment. The role is intentionally broader than AI security:…
Added 2 hours ago
Intern - Advanced Process Control (R2R)
Micron Technology
Boise
A Process Control Engineer Intern in Micron’s Technology Development team will participate in the development of process and equipment control solutions. In this position, you'll have the…
Added 2 hours ago
MT
Fab Equipment Engineer - SWE
Micron Technology
Manassas
- $73,000 to $183,000 USD / year
As an Equipment Engineer, you will ensure the reliability, performance, and continuous improvement of advanced semiconductor manufacturing equipment by solving complex technical challenges,…
Added 2 hours ago
SRAM Design Lead
Micron Technology
Boise · Albany
Micron is seeking an experienced SRAM Design Engineer to develop high-performance, low-power embedded memory IP and testchip content. This is for advanced semiconductor technologies. The…
Added 2 hours ago
Sr. Yield Enhancement Electrical Failure Analysis Engineer
Micron Technology
Boise
…Overview The Yield Enhancement Electrical Failure Analysis Engineer performs investigative electrical failure analysis to identify, categorize, and resolve defect issues impacting yield.…
Added 2 hours ago
Principal Software Engineer - Simulation Data, Validation & Infrastructure
Irving, TX
…high-fidelity simulation, scalable GPU computing, intelligent automation, and rigorous validation. This Principal Engineer role is a hands-on technical leadership position responsible for…
Added 2 hours ago
Principal Software Engineer - Robotics & Physical AI Simulation
Irving, TX
…high-fidelity simulation, scalable GPU computing, intelligent automation, and rigorous…
Added 2 hours ago
Principal Software Engineer - Digital Twin and Simulation Platform
Irving, TX
…high-fidelity simulation, scalable GPU computing, intelligent automation, and rigorous…
Added 2 hours ago
Principal Software Engineer - Agentic AI & Simulation Automation
Irving, TX
…high-fidelity simulation, scalable GPU computing, intelligent automation, and rigorous…
Added 2 hours ago
DevOps II / SRE
Robert Half
Philadelphia, PA
We are seeking a DevOps II / Site Reliability Engineer to help build and mature a growing Site Reliability Engineering (SRE) function supporting large-scale digital platforms. This role…

Closed listing

Genentech

Senior Software Engineer - Lab Automation

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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