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Added 1 min ago
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Software Technical Program Mgr - Hardware Asset Mg
Kforce
Long Beach, CA
- $80 to $90 USD / hour
Kforce has a client in Long Beach, CA that is seeking an experienced Hardware Asset Management Program Manager to support complex software engineering programs. This individual will partner…
Added 1 min ago
Marketing Operations Manager
Twilio
Remote, United States
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Added 2 mins ago
Senior HR Partner, Harvard College
Harvard University
Cambridge, MA
…Harvard University. It is the home of Harvard’s undergraduate program (Harvard College, founded in 1636) as well as all of Harvard’s Ph.D. programs (the Harvard Kenneth C. Griffin Graduate…
Added 2 mins ago
Technical Program Manager (Secret)
ASRC Federal Holding Company
Washington, DC
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Added 3 mins ago
Medical Director – Physical Medicine and Rehabilitation
The Elevance Health Companies, Inc.
United States
…autonomy. This approach promotes productivity, supports work-life integration, and ensures essential face-to-face onboarding and skill development. Please note that per our policy on…
Added 5 mins ago
SS
Application Manager, Vice President
State Street
Boston, MA
- $120,000 to $202,500 USD / year
Serves as senior lead in Securities Finance initiatives, working on new technologies and innovative solutions for the business. Analyzes, designs, develops software applications to support…
Added 5 mins ago
Manager, Database Administration
ExactCare Pharmacy, LLC
Remote, United States
The Manager, Database Administration will provide both technical leadership and operational oversight, ensuring database systems are scalable, reliable, secure, and aligned with enterprise…
Added 5 mins ago
Senior Technical Product Manager - APIs & Integrations
ComPsych Corporation
UNAVAILABLE
The Senior Technical Product Manager, APIs & Integrations will be a key member of the Product team. This role will be responsible for the end-to-end lifecycle of our API and integration…
Added 7 mins ago
Lead Program Manager - Digital
Sonepar
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…our digital capabilities, we are seeking an experienced Lead Program Manager - Digital to lead complex, cross-functional programs that enable our strategic business and digital priorities.…
Added 8 mins ago
Quality Engineering Student Program
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This student program will follow an in-person model. Students will be based at the Stellantis Headquarters & Technology Center in Auburn Hills, Michigan. Students are expected to work 24…
Added 9 mins ago
Scrum Master
SABEL SYSTEMS TECHNOLOGY SOLUTIONS LLC
Remote, United States
Support Release Planning / Program Increment (PI) Planning workshops by preparing team inputs, identifying dependencies, and helping define sprint-level deliverables.
Added 9 mins ago
Program Manager of Integrations
The Tustin Group
Norristown, PA
The Program Manager of Integrations leads the successful integration of acquired companies into The Tustin Group. This role coordinates cross-functional activities, manages integration…
Added 13 mins ago
Controls Program Manager
Johnson Controls Inc.
United States
The Systems Enablement Program Manager provides end-to-end program management for strategic deployment and execution planning initiatives. You will translate improvement priorities into…
Added 16 mins ago
CA
Program Manager (Data Center Hardware)
Computacenter AG & Co. oHG
OR
- $145,000 to $155,000 USD / year
The Program Manager (PM) is the main touch point and first escalation path for large customer engagements. The role is focused on overall account management including responsibility for all…
Added 17 mins ago
Manager, Healthcare Services
Molina Talent Acquisition
Florida City, FL
Assists in implementing care management, utilization management, behavioral health, care transitions, LTSS and other program activities in accordance with regulatory, contract standards and…
Added 17 mins ago
Supervisor, Healthcare Services
Molina Talent Acquisition
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Assists in implementing care management, utilization management, behavioral health, care transitions, LTSS and other program activities in accordance with regulatory, contract standards and…
Added 18 mins ago
Event and AV Operations Analyst
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Austin, TX
…high-pressure situations. This position reports to the Senior Manager, Live Events and Video Production…
Added 21 mins ago
Security Manager
Odyssey Systems Consulting Group, Ltd.
Hanscom AFB, MA
Odyssey Systems has an exciting opportunity for a Security Manager providing support to Program Acquisition Executive for Nuclear Command, Control, Communications Integration Directorate…
Added 21 mins ago
Senior Security Manager
Odyssey Systems Consulting Group, Ltd.
Hanscom AFB, MA
Odyssey Systems has an exciting opportunity for a Senior Security Manager providing support to Program Acquisition Executive for Nuclear Command, Control, Communications Integration…
Added 22 mins ago
Manager Informatics
Aetna Resources, LLC
Remote, United States
Assesses the requirements of the informatics department and identifies integration opportunities for new technologies and system processes.
Added 23 mins ago
Senior Technical Program Manager, Dedrone
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Washington, DC
As a Senior Technical Program Manager, you will own the end-to-end launch of the organization's counter-UAS Solution offerings, from readiness through field deployment. You will work at the…
Added 26 mins ago
Senior Global Solutions Architect
Five9
Remote, United States
…technical architecture expertise with a strong grasp of customer business strategy - translating data, systems, and workflows into a clear, forward-looking roadmap that drives measurable…
Added 29 mins ago
Enterprise Asset Manager / Project Manager
ITnova
Philadelphia, PA
ITnova is seeking an experienced Enterprise Asset Manager / Project Manager to lead and support the Department of Aviation's Enterprise Asset Management (EAM) Program at Philadelphia…
Added 33 mins ago
EU
Delivery Lead (NC)
Experis USA
Charlotte, NC
- $64.53 USD / hour
Experience in roles such as Program Manager, Project Manager, Delivery Lead, or equivalent.
Added 33 mins ago
Change Management Lead
Prime Controls
Lewisville, TX
Established in 2004, Prime Controls, L.P. is a family-owned Systems Integration and I&C Construction firm dedicated to meeting clients’ industrial automation and control requirements. As a…

Closed listing

Genentech

Portfolio Operations Manager

Los Angeles, CA, United States

$142,200 to $264,200 USD / year

This opening has closed.

The original listing is kept below for reference.

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About employer

Job details

Pay: $142,200 to $264,200 USD / year
Education: Bachelor’s degree
Posting language: English
Posted: Nov 2, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position From the beginning, Genentech has been a team of highly dedicated, passionate individuals. We are a place where people are united around a single purpose and an ambitious vision. Together, we aspire to deliver ever better health outcomes for patients while lowering overall healthcare costs. Our goal is to compel the customer to act on behalf of their patients while showing great commitment to the rare disease community, whose support is key. Utilizing innovative methods to identify patients who may benefit from treatment, we must take a highly strategic approach to patient access while assisting patients and their caregivers to navigate the healthcare system.

POSITION SUMMARY

The Portfolio Operations Manager is responsible for the operating system that allows CE to evaluate, prioritize, sequence, and govern enterprise work as one portfolio. This role owns intake of proposed enterprise work, the prioritized CE portfolio roadmap, governance and decision cadence, and the integrated view of dependencies, duplication, capacity, and tradeoffs. The manager partners with CE Leadership, Enterprise Operations, Regions, HEDs, RBO teams, and other stakeholders to ensure the organization focuses resources on the work that matters most and can make transparent portfolio decisions when priorities compete.

SCOPE & KEY RESPONSIBILITIES

Enterprise Portfolio Strategy & Roadmap

Maintain the integrated CE enterprise portfolio across initiatives, launches, RBO work, and field-partner commitments.
Translate CE strategy and leadership priorities into a prioritized portfolio roadmap.
Create visibility to timing, sequencing, interdependencies, and major portfolio milestones.
Identify duplication, overlap, and opportunities to combine or simplify work across the portfolio.
Ensure portfolio views are current, decision-oriented, and useful to CE Leadership and operating teams.

Intake, Evaluation & Prioritization

Own the intake and evaluation process for proposed enterprise work.
Establish clear criteria for strategic alignment, impact, urgency, effort, capacity, and enterprise value.
Facilitate prioritization discussions and develop recommendations when demand exceeds available capacity.
Ensure new work has a clear sponsor, problem statement, intended outcome, and required decision before entering the portfolio.
Route approved work to the appropriate Enterprise Operations manager, lead, or enabling team for execution.

Portfolio Governance & Decision Support

Manage the portfolio governance cadence and prepare decision materials for CE Leadership and CELT as needed.
Create transparent decision logs, escalation paths, and follow-through on portfolio choices.
Provide concise synthesis of what is changing, why it matters, and what decisions or tradeoffs are required.
Ensure governance focuses on material decisions, risks, and dependencies rather than routine status reporting.
Partner with initiative and launch teams to maintain accurate portfolio status and milestone visibility.

Capacity, Dependencies & RBO Integration

Maintain an integrated view of enterprise capacity, demand, major dependencies, and resource constraints.
Develop capacity, sequencing, and tradeoff recommendations across competing priorities.
Integrate RBO work into the broader CE portfolio view so Regional and HED-supported commitments are visible and prioritized.
Surface cross-portfolio risks and constraints early enough to enable leadership action.
Partner with Enterprise Initiatives and Launch Operations to resolve conflicts and coordinate shared resources.

Team Leadership & Portfolio Discipline

Lead, coach, and develop Enterprise Operations Leads assigned to portfolio and RBO work.
Set standards for portfolio data quality, governance materials, decision support, and milestone tracking.
Allocate team capacity to the highest-priority portfolio needs and time-sensitive decisions.
Build strong portfolio management capabilities, tools, and ways of working across the team.
Contribute to common Enterprise Operations standards, talent practices, and continuous improvement.

KEY DELIVERABLES

Prioritized CE enterprise portfolio roadmap
Enterprise intake and evaluation process
Portfolio governance calendar and decision materials
Capacity, sequencing, and tradeoff recommendations
Integrated dependency, risk, and milestone view
RBO portfolio and commitment visibility
Executive portfolio dashboards and outcome reviews
Portfolio standards, templates, and decision logs

MINDSET & CAPABILITIES

Enterprise thinker who prioritizes the whole over individual workstreams
Strong judgment on value, urgency, effort, and tradeoffs
Able to turn complexity into transparent portfolio choices
Analytical and comfortable synthesizing imperfect information
Strong facilitator of senior-level prioritization and decision discussions
Skilled at influencing without formal authority
Disciplined about governance without creating unnecessary bureaucracy
Proactive in identifying capacity constraints, dependencies, and duplication
Strong communication and executive synthesis capabilities
Collaborative people leader and developer of talent
Strong drive for results with an enterprise and customer mindset

REQUIRED QUALIFICATIONS

Bachelor's degree required
8-10 years of pharmaceutical, biotechnology, consulting, commercial, portfolio, strategy, program management, and/or operations experience including leading, coaching or mentoring others strongly preferred
Demonstrated experience with portfolio management, prioritization, governance, or resource planning
Experience facilitating senior leadership decisions involving competing priorities and tradeoffs
Strong analytical, synthesis, and project/program management capabilities
Demonstrated ability to influence across a complex matrixed organization
Strong communication and executive presentation skills
Ability and willingness to travel as required for internal and external business meetings

PREFERRED QUALIFICATIONS

Graduate-level degree (e.g., MBA or advanced life sciences degree)
Prior commercial operations, portfolio management, strategy, or transformation experience
Experience supporting large-scale field organizations, RBO, or enterprise planning processes

Location: This position can be based in SSF or Remote. Relocation benefits are not available.

The expected salary range for this position based on the primary location of CA is $142,200 - $264,200 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

About employer

More about this job

Skills

Leadership
Prioritization
Reporting
Team leadership
Process improvement
Communication skills
Biotechnology
Program management
Coaching
Presentation skills

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