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Added 5 mins ago
Software Engineer - Product (Technical Leadership)
Meta
Charleston, WV
Experience utilizing data and analysis to explain technical problems and provide detailed feedback and solutions
Added 5 mins ago
Sr. Application Security Engineer
American Express Global Business Travel
Charleston, WV
…application development into application security, bringing a developer's mindset to security and operations, and will mentor others while helping shape how the organization builds and…
Added 5 mins ago
Lead Software Developer
Lumen
Charleston, WV
As a Lead Software Developer, they design, develop, test, debug, and enhance software solutions of moderate complexity while collaborating across disciplines to bring ideas to life. They…
Added 5 mins ago
AT
Software Engineer II
Akamai Technologies, Inc.
Charleston, WV
- $95,000 to $171,000 USD / year
Are you a software developer who loves solving complex problems?
Added 5 mins ago
Principal Software Engineer
Lyric
Charleston, WV
…collaborating with cross-functional teams to deliver innovative solutions. By leveraging extensive technical expertise, the position will guide and mentor engineers, champion best…
Added 5 mins ago
Security Engineer
Meta
Charleston, WV
3+ years programming experience with at least one of the following languages: Python, PHP, Ruby, or similar scripting languages
Added 10 mins ago
SDE III Conversational AI Developer
Full Potential Solutions
Remote, United States
Full Potential Solutions (FPS) is a performance-based, analytically driven omnichannel solutions organization with operations in Waltham, MA, Chennai, India, Bogota, Colombia, and Manila,…
Added 13 mins ago
Software Engineer - Product (Technical Leadership)
Meta
Indianapolis, IN
Experience utilizing data and analysis to explain technical problems and provide detailed feedback and solutions
Added 13 mins ago
Agentic AI Engineer, Senior
Deloitte
Indianapolis, IN
2+ years of hands-on experience building AI/ML solutions using Python
Added 13 mins ago
Databricks Data Engineer
Deloitte
Indianapolis, IN
Design, build, and maintain data pipelines and data engineering solutions using Databricks, Apache Spark, Python, and Structured Query Language (SQL)
Added 13 mins ago
Agentic AI Engineer, Senior - Anthropic/Claude
Deloitte
Indianapolis, IN
…to build, deploy, and operate integrated/verticalized sector solutions in software, data, AI, network, and hybrid cloud infrastructure. These solutions are powered by engineering for…
Added 13 mins ago
Sr. Application Security Engineer
American Express Global Business Travel
Indianapolis, IN
…application development into application security, bringing a developer's mindset to security and operations, and will mentor others while helping shape how the organization builds and…
Added 13 mins ago
Agentic AI Engineer - Anthropic/Claude
Deloitte
Indianapolis, IN
…to build, deploy, and operate integrated/verticalized sector solutions in software, data, AI, network, and hybrid cloud infrastructure. These solutions are powered by engineering for…
Added 13 mins ago
Lead Software Developer
Lumen
Indianapolis, IN
As a Lead Software Developer, they design, develop, test, debug, and enhance software solutions of moderate complexity while collaborating across disciplines to bring ideas to life. They…
Added 13 mins ago
Lead Integration Engineer II
Deloitte
Indianapolis, IN
…to build, deploy, and operate integrated/verticalized sector solutions in software, data, AI, network, and hybrid cloud infrastructure. These solutions are powered by engineering for…
Added 13 mins ago
Data Engineer II
Deloitte
Indianapolis, IN
…intelligence (AI), machine learning (ML), and generative AI (GenAI) solutions, ensuring data is trusted, secure, observable, and scalable from ingestion through consumption. You will design…
Added 13 mins ago
AT
Software Engineer II
Akamai Technologies, Inc.
Indianapolis, IN
- $95,000 to $171,000 USD / year
Are you a software developer who loves solving complex problems?
Added 14 mins ago
Associate Director - CFIB Deal Enablement & Operations
Lilly
Indianapolis, IN
…(e.g., LLM-based workflows, agentic tools, prompt engineering, Python, or Power Platform), with the judgment to know where AI does and does not belong in a deal…
Added 14 mins ago
Cyber Data Privacy - Consultant
Deloitte
Indianapolis, IN
Understand marketing technologies, including customer data platforms, consent, cookies, tag management solutions
Added 14 mins ago
Principal Software Engineer
Lyric
Indianapolis, IN
…collaborating with cross-functional teams to deliver innovative solutions. By leveraging extensive technical expertise, the position will guide and mentor engineers, champion best…
Added 14 mins ago
Senior Backend Software Engineer - Kalepa for Operations
Jobgether
Remote, United States
…support complex business workflows. Working primarily with Python and AWS, you will help develop intelligent systems capable of processing massive volumes of unstructured information with…
Added 14 mins ago
Senior Software Engineer/Tech Lead
Lilly
Indianapolis, IN
…design, code, and deliver critical components (primarily in Python) while overseeing development teams through design reviews, technical guidance, and quality gates to ensure solutions are…
Added 14 mins ago
Security Engineer
Meta
Indianapolis, IN
3+ years programming experience with at least one of the following languages: Python, PHP, Ruby, or similar scripting languages
Added 14 mins ago
Configuration Engineer Advisor
Elevance Health
Indianapolis, IN
…capabilities to support federal programs. The organization delivers solutions across claims administration, data, and care delivery to help address complex challenges and improve health…
Added 26 mins ago
Senior Technical Lead Architecture - Enterprise Risk Delivery
Intermedia Group, Inc.
Mc Lean, VA
The Sr. Tech Lead of Solutions Architecture is a key team member of the company's Enterprise Risk Business Technology Team within Enterprise Risk Organization.

Genentech

Lead Engineer, Autonomous Lab Platforms

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $169,100 - 314,100 of hiring range.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $169,100 - 314,100 of hiring range.
Posting language: English
Posted: Oct 30, 2026

Original job description

The Position The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

Advances in AI, data, robotics, and laboratory automation are transforming drug discovery and development. The Roche Autonomous Lab Accelerator brings together gRED, pRED, PT, and the Computational Sciences Center of Excellence (CS CoE) to build closed-loop Lab-in-the-Loop capabilities that connect scientific intent, digital design, experimental execution, and high-quality data generation.

The Opportunity

You are the technical lead for Lab Automation within Automation Science & Technology and the owner of the physical platform architecture for the Roche Autonomous Lab Accelerator. This role reports to the Head, Automation Science & Technology, Autonomous Lab Accelerator.

Working closely with Science & Technology Project Leaders, scientific SMEs, Lab Operations, and Lab Automation Informatics partners, you translate defined scientific workflow requirements into executable laboratory processes and scalable physical automation platforms. The individual in this role would own how scientific requirements are technically realized through robotics, instrumentation, instrument-control software, execution-layer interfaces, and integrated laboratory systems. You also partner with Lab Operations from design through operational acceptance so new capabilities are engineered for autonomous, reliable, and supportable routine use.

In this role, you will:

Key Responsibilities

Physical Platform Architecture: Own the end-to-end architecture of the physical execution platform, from instruments and robotic work cells to integrated, increasingly unattended laboratory systems. Serve as the technical design authority for robotics, scientific instrumentation, instrument-control software, execution-layer interfaces, and reusable platform patterns.
Scientific Workflow Translation & Execution Design: Partner with Science & Technology Project Leaders and scientific SMEs to convert defined scientific requirements and acceptance criteria into automatable unit operations, equipment requirements, sample and material flows, execution sequences, control points, and exception states. Identify technical constraints and recommend workflow adaptations required for robust automated execution.
AI-to-Execution & Data Interfaces: Partner with CS CoE to define the boundary between digital orchestration and physical execution: how digitally specified experiments become machine-executable actions and how instrument outputs, system state, sample identity, metadata, and execution context return to downstream systems. Own the physical-platform interface and device requirements while CS CoE owns the corresponding higher-level AI, informatics, and orchestration capabilities.
Build, Commission & Technical Verification: Lead technical selection, integration, commissioning, and verification of robotics, liquid handlers, scientific instruments, schedulers, and control layers. Demonstrate that new platforms satisfy defined technical and scientific requirements before they progress to operational acceptance.
Autonomy, Operability & Operational Handoff: Engineer the capabilities required for unattended execution, including state awareness, observability, exception detection, automated recovery, safe-stop behavior, and appropriate human escalation. Design for maintainability and serviceability, jointly define operational-readiness criteria with Lab Operations, and support formal acceptance into routine operations. After acceptance, remain the technical design authority for material architecture changes, new capabilities, and systemic technical limitations; Lab Operations owns routine execution, monitoring, maintenance, incident response, and established recovery procedures.
Technical Leadership & Reuse: Lead complex technical problem solving, architecture and design reviews, and the development of reusable engineering standards. Mentor engineers and direct contractors, vendors, and system integrators while communicating technical tradeoffs clearly across science, software, automation, facilities, and operations.

Key Deliverables

Physical Platform Reference Architecture: A scalable architecture for the Accelerator physical execution layer and clearly defined interfaces with CS CoE systems.
Integrated Autonomous Capabilities: Priority laboratory automation platforms delivered from defined scientific requirements through commissioning, technical verification, and scientific acceptance.
Reusable Engineering Standards: Common patterns for instrument and robotic integration, execution state, data capture, observability, error handling, recovery, and deployment across the organization.
Operational Readiness & Transfer: Joint readiness criteria and handoff packages that enable Lab Operations to formally accept new systems into reliable routine use, with clear post-deployment ownership for operations versus engineering changes.

Who you are:

Education & Experience: Bachelor's or advanced degree in engineering, computer science, life sciences, or a related discipline, with significant experience in laboratory automation and systems integration.
Automation & Systems Expertise: Deep experience designing, programming, integrating, and deploying laboratory automation platforms such as Hamilton, Tecan, Agilent, HighRes, Opentrons, robotic arms, schedulers, or comparable technologies.
Software & Integration Fluency: Strong Python and API-integration skills, with experience connecting instruments to schedulers, databases, message brokers, LIMS/ELN, or other scientific software systems.
End-to-End Delivery: Demonstrated ownership of greenfield automation platforms from architecture and vendor selection through commissioning and production deployment, with strong systems thinking across hardware, software, data, science, and reliability.
Technical Leadership: Proven ability to lead through technical authority, mentor engineers, and create reusable solutions in ambiguous, cross-functional environments while remaining hands-on when needed.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $169,100 - 314,100 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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More about this job

Skills

Workflow
Robotics
Translation
Incident response
Leadership
Problem solving
Computer science
Python
LIMS
Systems thinking

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