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Added 6 mins ago
Senior Accident Reconstructionist
Knott Laboratory LLC
PHOENIX, AZ · Nashville, TN · AUSTIN, TX · Las Vegas, NV · Chicago, IL · Dallas, TX · Denver, CO
Lead complex accident reconstruction investigations involving passenger vehicles, commercial vehicles, motorcycles, bicycles, pedestrians, and other transportation-related incidents, as…
Added 6 mins ago
Transmission Line Engineer (Senior or Principal)
Xcel Energy Services Inc
Amarillo, TX
Applies extensive technical expertise of transmission line engineering and construction. Performs as a project lead on new transmission line projects. Carries out complex or innovative…
Added 6 mins ago
Big Data Systems Engineer
KBR
Niceville, FL · Denver, CO · Huntsville, AL · Los Angeles, CA · Tampa, FL · Washington, DC
The Big Data Systems Engineer will work on the deployment and integration of a highly visible data analytic project called Cloud Hybrid Edge-to-Enterprise Evaluation Test & Analysis Suite…
Added 7 mins ago
Senior Backend Engineer - Microservices
GD Information Technology, Inc.
Remote, United States
Engineer solutions leveraging Google Cloud Platform (Cloud Run, GKE, Pub/Sub, BigQuery)
Added 7 mins ago
Asset Services Technical Director
US AMR-Jones Lang LaSalle Americas, Inc.
Remote, United States
Provides support for executive oversight of project management staff nationally, ensuring consistent application of policies, technical standards, and operational procedures across all…
Added 8 mins ago
Staff Engineer, Project Engineering
Thermo Fisher Scientific
St. Louis, MO
…(pre)clinical trials and commercial applications. The Staff Engineer role is part of the Engineering team and reports to the Manager of Manufacturing Engineering. This role focuses on…
Added 8 mins ago
Staff Validation Engineer
Thermo Fisher Scientific
Greenville, NC
…healthcare and scientific advancement. As a Staff Validation Engineer, you'll lead validation activities for critical systems, equipment, and processes that enable the development and…
Added 8 mins ago
LEAD Field Engineer - 2027
Baker Hughes Oilfield Operations LLC
OTHER ILLINOIS, IL · OTHER OKLAHOMA, OK
Join the LEAD Field Engineer Development Program
Added 11 mins ago
Project Manager Pipeline
True Oil LLC
Casper, WY
Lead multidisciplinary project teams and provide overall project leadership from planning through commissioning.
Added 12 mins ago
UP
Validation - Engineer III/Lead - Project Farma
USPF PROJECT FARMA LLC
Customer Site, IN · Customer Site, WI · Customer Site, KS · Customer Site, MO · Customer Site, OH · Customer Site, IL
- $80,000 to $115,000 USD / year
The Validation Lead Engineer is an advanced individual contributor with demonstrated depth in their technical discipline and a growing record of leading complex workstreams. This role…
Added 14 mins ago
Integration Engineer
CO1 First Orion Corp
North Little Rock, AR
We are looking for an Integrations Engineer who helps lead implementations of First Orion solutions and/or manages complex change that significantly impact an existing solution.
Added 14 mins ago
Project Engineer
Novaspect, Inc.
Schaumburg, IL
…systems and solutions, is currently offering an opportunity for a Project Engineer to join our fast growing team! The Project Engineer will assist our automation and Distributed Control…
Added 14 mins ago
Technical Program Manager
Apple
Cupertino, CA
- Act as lead engineer on a variety of projects and participates in the project planning of major sub-projects.
Added 20 mins ago
Production Engineer - Formaldehyde
Capital Resin Corporation
Columbus, OH
We have an immediate opening for a “Production Engineer - HCHO.” This position will be based out of our Columbus, Ohio plant. Responsibilities will include supporting our Columbus, Ohio and…
Added 22 mins ago
Transportation Planner II
City of Charlotte
United States
The Charlotte Department of Transportation (CDOT) is seeking a Transportation Planner to lead and advance the city’s Shared Micromobility Program within the department's Mobility Planning…
Added 23 mins ago
Lead Space Systems Engineer
The MITRE Corporation
Chantilly, VA
MITRE is seeking a technically exceptional Lead Space System Engineer to support the National Reconnaissance Office (NRO) Advanced Systems & Technology Directorate (AS&T) Accelerate System…
Added 24 mins ago
J
MANAGER, BRIDGES AND STRUCTURES (DEPARTMENT OF TRANSPORATION AND HIGHWAYS) ACTIVELY RECRUITED
IL
- $143,406 to $158,337 USD / year
Current registration in the State of Illinois as a Licensed Professional Engineer is required.
Added 26 mins ago
Sr. Project Engineer
DPR GP
San Diego, CA
…role and is a starting point. Every employee is expected to lead from where they are, take ownership of outcomes, and always act in the best interest of the team, customer, project and…
Added 26 mins ago
Senior Electrical Engineer
Enovation Controls LLC
Tulsa, OK
The Senior Electrical Engineer position requires advanced expertise in electrical engineering principles to lead the development of innovative solutions for our customers. This position…
Added 26 mins ago
Manager, Program Management
Kansas City, MO
This role partners closely with field personnel, project owners, and finance teams to provide monthly insights, production reviews, and forecast accuracy for a $1.2B engineering capital…
Added 28 mins ago
Network Engineer IV
Chenega Corp
UNAVAILABLE, VA
The Network Engineer IV provides advanced network engineering and operational support for DOI/IA enterprise network environments, including LAN, WAN, WLAN, VoIP, and security-related…
Added 28 mins ago
A
Civil Engineer
Actalent
Spokane, WA
- $115,000 to $145,000 USD / year
Job Title: Senior Civil EngineerJob DescriptionWe are seeking an experienced Senior Civil Engineer to lead and support site development projects in the Spokane area. This person will be…
Added 28 mins ago
A
Civil Engineer
Actalent
Spokane, WA
- $115,000 to $145,000 USD / year
Job Title: Senior Civil EngineerJob DescriptionWe are seeking an experienced Senior Civil Engineer to lead and support site development projects in the Spokane area. This person will be…
Added 28 mins ago
Manager-Facilities Project Management (Proj Construction or Proj Develp.)
Dominion Energy
RICHMOND, VA
Ability to lead, develop, and mentor project-management professionals and delivery teams
Added 30 mins ago
RE
Engineer I
Rosendin Electric, Inc
United States
- $85,200 to $111,900 USD / year
The Engineer I is an entry-level engineering position and is expected to learn and develop competency in the Essential Duties and Responsibilities. Part of the responsibility will be to…

Closed listing

Genentech

Lead Engineer, Autonomous Lab Platforms

South San Francisco, CA, United States

The expected salary range for this position based on the primary location of San Francisco is $169,100 - 314,100 of hiring range.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $169,100 - 314,100 of hiring range.
Posting language: English
Posted: Oct 30, 2026

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Original job description

Archived listing. The details below describe a past opening.

The Position The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

Advances in AI, data, robotics, and laboratory automation are transforming drug discovery and development. The Roche Autonomous Lab Accelerator brings together gRED, pRED, PT, and the Computational Sciences Center of Excellence (CS CoE) to build closed-loop Lab-in-the-Loop capabilities that connect scientific intent, digital design, experimental execution, and high-quality data generation.

The Opportunity

You are the technical lead for Lab Automation within Automation Science & Technology and the owner of the physical platform architecture for the Roche Autonomous Lab Accelerator. This role reports to the Head, Automation Science & Technology, Autonomous Lab Accelerator.

Working closely with Science & Technology Project Leaders, scientific SMEs, Lab Operations, and Lab Automation Informatics partners, you translate defined scientific workflow requirements into executable laboratory processes and scalable physical automation platforms. The individual in this role would own how scientific requirements are technically realized through robotics, instrumentation, instrument-control software, execution-layer interfaces, and integrated laboratory systems. You also partner with Lab Operations from design through operational acceptance so new capabilities are engineered for autonomous, reliable, and supportable routine use.

In this role, you will:

Key Responsibilities

Physical Platform Architecture: Own the end-to-end architecture of the physical execution platform, from instruments and robotic work cells to integrated, increasingly unattended laboratory systems. Serve as the technical design authority for robotics, scientific instrumentation, instrument-control software, execution-layer interfaces, and reusable platform patterns.
Scientific Workflow Translation & Execution Design: Partner with Science & Technology Project Leaders and scientific SMEs to convert defined scientific requirements and acceptance criteria into automatable unit operations, equipment requirements, sample and material flows, execution sequences, control points, and exception states. Identify technical constraints and recommend workflow adaptations required for robust automated execution.
AI-to-Execution & Data Interfaces: Partner with CS CoE to define the boundary between digital orchestration and physical execution: how digitally specified experiments become machine-executable actions and how instrument outputs, system state, sample identity, metadata, and execution context return to downstream systems. Own the physical-platform interface and device requirements while CS CoE owns the corresponding higher-level AI, informatics, and orchestration capabilities.
Build, Commission & Technical Verification: Lead technical selection, integration, commissioning, and verification of robotics, liquid handlers, scientific instruments, schedulers, and control layers. Demonstrate that new platforms satisfy defined technical and scientific requirements before they progress to operational acceptance.
Autonomy, Operability & Operational Handoff: Engineer the capabilities required for unattended execution, including state awareness, observability, exception detection, automated recovery, safe-stop behavior, and appropriate human escalation. Design for maintainability and serviceability, jointly define operational-readiness criteria with Lab Operations, and support formal acceptance into routine operations. After acceptance, remain the technical design authority for material architecture changes, new capabilities, and systemic technical limitations; Lab Operations owns routine execution, monitoring, maintenance, incident response, and established recovery procedures.
Technical Leadership & Reuse: Lead complex technical problem solving, architecture and design reviews, and the development of reusable engineering standards. Mentor engineers and direct contractors, vendors, and system integrators while communicating technical tradeoffs clearly across science, software, automation, facilities, and operations.

Key Deliverables

Physical Platform Reference Architecture: A scalable architecture for the Accelerator physical execution layer and clearly defined interfaces with CS CoE systems.
Integrated Autonomous Capabilities: Priority laboratory automation platforms delivered from defined scientific requirements through commissioning, technical verification, and scientific acceptance.
Reusable Engineering Standards: Common patterns for instrument and robotic integration, execution state, data capture, observability, error handling, recovery, and deployment across the organization.
Operational Readiness & Transfer: Joint readiness criteria and handoff packages that enable Lab Operations to formally accept new systems into reliable routine use, with clear post-deployment ownership for operations versus engineering changes.

Who you are:

Education & Experience: Bachelor's or advanced degree in engineering, computer science, life sciences, or a related discipline, with significant experience in laboratory automation and systems integration.
Automation & Systems Expertise: Deep experience designing, programming, integrating, and deploying laboratory automation platforms such as Hamilton, Tecan, Agilent, HighRes, Opentrons, robotic arms, schedulers, or comparable technologies.
Software & Integration Fluency: Strong Python and API-integration skills, with experience connecting instruments to schedulers, databases, message brokers, LIMS/ELN, or other scientific software systems.
End-to-End Delivery: Demonstrated ownership of greenfield automation platforms from architecture and vendor selection through commissioning and production deployment, with strong systems thinking across hardware, software, data, science, and reliability.
Technical Leadership: Proven ability to lead through technical authority, mentor engineers, and create reusable solutions in ambiguous, cross-functional environments while remaining hands-on when needed.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $169,100 - 314,100 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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More about this job

Skills

Workflow
Robotics
Translation
Incident response
Leadership
Problem solving
Computer science
Python
LIMS
Systems thinking

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